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Notch 2-positive progenitors with the intrinsic ability to give rise to pancreatic ductal cells.
Lee KM, Yasuda H, Hollingsworth MA, Ouellette MM. Lee KM, et al. Among authors: ouellette mm. Lab Invest. 2005 Aug;85(8):1003-12. doi: 10.1038/labinvest.3700298. Lab Invest. 2005. PMID: 15924149
Immortalization with telomerase of the Nestin-positive cells of the human pancreas.
Lee KM, Nguyen C, Ulrich AB, Pour PM, Ouellette MM. Lee KM, et al. Among authors: ouellette mm. Biochem Biophys Res Commun. 2003 Feb 21;301(4):1038-44. doi: 10.1016/s0006-291x(03)00086-x. Biochem Biophys Res Commun. 2003. PMID: 12589817
Apoptosis induced by adenovirus-mediated p14ARF expression in U2OS osteosarcoma cells is associated with increased Fas expression.
Kim M, Sgagias M, Deng X, Jung YJ, Rikiyama T, Lee K, Ouellette M, Cowan K. Kim M, et al. Biochem Biophys Res Commun. 2004 Jul 16;320(1):138-44. doi: 10.1016/j.bbrc.2004.05.135. Biochem Biophys Res Commun. 2004. PMID: 15207713
Culture and immortalization of pancreatic ductal epithelial cells.
Lawson T, Ouellette M, Kolar C, Hollingsworth M. Lawson T, et al. Methods Mol Med. 2005;103:113-22. doi: 10.1385/1-59259-780-7:113. Methods Mol Med. 2005. PMID: 15542901 Review.
Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells.
Salaria SN, Illei P, Sharma R, Walter KM, Klein AP, Eshleman JR, Maitra A, Schulick R, Winter J, Ouellette MM, Goggins M, Hruban R. Salaria SN, et al. Among authors: ouellette mm. Cancer Biol Ther. 2007 Mar;6(3):324-8. doi: 10.4161/cbt.6.3.3904. Epub 2007 Mar 24. Cancer Biol Ther. 2007. PMID: 17404500 Free PMC article.
Class III beta-tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia.
Lee KM, Cao D, Itami A, Pour PM, Hruban RH, Maitra A, Ouellette MM. Lee KM, et al. Among authors: ouellette mm. Histopathology. 2007 Oct;51(4):539-46. doi: 10.1111/j.1365-2559.2007.02792.x. Epub 2007 Aug 21. Histopathology. 2007. PMID: 17714470
Ras-driven transformation of human nestin-positive pancreatic epithelial cells.
Campbell PM, Lee KM, Ouellette MM, Kim HJ, Groehler AL, Khazak V, Der CJ. Campbell PM, et al. Among authors: ouellette mm. Methods Enzymol. 2008;439:451-65. doi: 10.1016/S0076-6879(07)00431-4. Methods Enzymol. 2008. PMID: 18374182
Sonic hedgehog promotes desmoplasia in pancreatic cancer.
Bailey JM, Swanson BJ, Hamada T, Eggers JP, Singh PK, Caffery T, Ouellette MM, Hollingsworth MA. Bailey JM, et al. Among authors: ouellette mm. Clin Cancer Res. 2008 Oct 1;14(19):5995-6004. doi: 10.1158/1078-0432.CCR-08-0291. Clin Cancer Res. 2008. PMID: 18829478 Free PMC article.
Use of exogenous hTERT to immortalize primary human cells.
Lee KM, Choi KH, Ouellette MM. Lee KM, et al. Among authors: ouellette mm. Cytotechnology. 2004 Jun;45(1-2):33-8. doi: 10.1007/10.1007/s10616-004-5123-3. Cytotechnology. 2004. PMID: 19003241 Free PMC article.
K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signaling pathways.
Matsuo Y, Campbell PM, Brekken RA, Sung B, Ouellette MM, Fleming JB, Aggarwal BB, Der CJ, Guha S. Matsuo Y, et al. Among authors: ouellette mm. Mol Cancer Res. 2009 Jun;7(6):799-808. doi: 10.1158/1541-7786.MCR-08-0577. Epub 2009 Jun 9. Mol Cancer Res. 2009. PMID: 19509115 Free PMC article.
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