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Identification of the tissue inhibitor of metalloproteinases-2 (TIMP-2) binding site on the hemopexin carboxyl domain of human gelatinase A by site-directed mutagenesis. The hierarchical role in binding TIMP-2 of the unique cationic clusters of hemopexin modules III and IV.
Overall CM, King AE, Sam DK, Ong AD, Lau TT, Wallon UM, DeClerck YA, Atherstone J. Overall CM, et al. J Biol Chem. 1999 Feb 12;274(7):4421-9. doi: 10.1074/jbc.274.7.4421. J Biol Chem. 1999. PMID: 9933646 Free article.
Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage.
Tam EM, Wu YI, Butler GS, Stack MS, Overall CM. Tam EM, et al. Among authors: overall cm. J Biol Chem. 2002 Oct 11;277(41):39005-14. doi: 10.1074/jbc.M206874200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145314 Free article.
286 results