Overeem AW - Search Results

1

Unequal Effects of Myosin 5B Mutations in Liver and Intestine Determine the Clinical Presentation of Low-Gamma-Glutamyltransferase Cholestasis.

van IJzendoorn SCD, Li Q, Qiu YL, Wang JS, Overeem AW. van IJzendoorn SCD, et al. Among authors: overeem aw. Hepatology. 2020 Oct;72(4):1461-1468. doi: 10.1002/hep.31430. Hepatology. 2020. PMID: 32583448 Free PMC article. Review. No abstract available.

2

A Molecular Mechanism Underlying Genotype-Specific Intrahepatic Cholestasis Resulting From MYO5B Mutations.

Overeem AW, Li Q, Qiu YL, Cartón-García F, Leng C, Klappe K, Dronkers J, Hsiao NH, Wang JS, Arango D, van Ijzendoorn SCD. Overeem AW, et al. Hepatology. 2020 Jul;72(1):213-229. doi: 10.1002/hep.31002. Epub 2020 Apr 23. Hepatology. 2020. PMID: 31750554 Free PMC article.

3

Pluripotent stem cell-derived bile canaliculi-forming hepatocytes to study genetic liver diseases involving hepatocyte polarity.

Overeem AW, Klappe K, Parisi S, Klöters-Planchy P, Mataković L, du Teil Espina M, Drouin CA, Weiss KH, van IJzendoorn SCD. Overeem AW, et al. J Hepatol. 2019 Aug;71(2):344-356. doi: 10.1016/j.jhep.2019.03.031. Epub 2019 Apr 6. J Hepatol. 2019. PMID: 30965071

4

Loss of MYO5B expression deregulates late endosome size which hinders mitotic spindle orientation.

Leng C, Overeem AW, Cartón-Garcia F, Li Q, Klappe K, Kuipers J, Cui Y, Zuhorn IS, Arango D, van IJzendoorn SCD. Leng C, et al. Among authors: overeem aw. PLoS Biol. 2019 Nov 4;17(11):e3000531. doi: 10.1371/journal.pbio.3000531. eCollection 2019 Nov. PLoS Biol. 2019. PMID: 31682603 Free PMC article.

5

Myo5b knockout mice as a model of microvillus inclusion disease.

Cartón-García F, Overeem AW, Nieto R, Bazzocco S, Dopeso H, Macaya I, Bilic J, Landolfi S, Hernandez-Losa J, Schwartz S Jr, Ramon y Cajal S, van Ijzendoorn SC, Arango D. Cartón-García F, et al. Among authors: overeem aw. Sci Rep. 2015 Jul 23;5:12312. doi: 10.1038/srep12312. Sci Rep. 2015. PMID: 26201991 Free PMC article.

6

Induction of Bile Canaliculi-Forming Hepatocytes from Human Pluripotent Stem Cells.

Matakovic L, Overeem AW, Klappe K, van IJzendoorn SCD. Matakovic L, et al. Among authors: overeem aw. Methods Mol Biol. 2022;2544:71-82. doi: 10.1007/978-1-0716-2557-6_4. Methods Mol Biol. 2022. PMID: 36125710

7

Mechanisms of apical-basal axis orientation and epithelial lumen positioning.

Overeem AW, Bryant DM, van IJzendoorn SC. Overeem AW, et al. Trends Cell Biol. 2015 Aug;25(8):476-85. doi: 10.1016/j.tcb.2015.04.002. Epub 2015 May 1. Trends Cell Biol. 2015. PMID: 25941134 Review.

8

The role of enterocyte defects in the pathogenesis of congenital diarrheal disorders.

Overeem AW, Posovszky C, Rings EH, Giepmans BN, van IJzendoorn SC. Overeem AW, et al. Dis Model Mech. 2016 Jan;9(1):1-12. doi: 10.1242/dmm.022269. Dis Model Mech. 2016. PMID: 26747865 Free PMC article. Review.

9

MYO5B, STX3, and STXBP2 mutations reveal a common disease mechanism that unifies a subset of congenital diarrheal disorders: A mutation update.

Dhekne HS, Pylypenko O, Overeem AW, Zibouche M, Ferreira RJ, van der Velde KJ, Rings EHHM, Posovszky C, van der Sluijs P, Swertz MA, Houdusse A, van IJzendoorn SCD. Dhekne HS, et al. Among authors: overeem aw. Hum Mutat. 2018 Mar;39(3):333-344. doi: 10.1002/humu.23386. Epub 2018 Jan 17. Hum Mutat. 2018. PMID: 29266534 Free PMC article. Review.

10

A molecular switch for the orientation of epithelial cell polarization.

Bryant DM, Roignot J, Datta A, Overeem AW, Kim M, Yu W, Peng X, Eastburn DJ, Ewald AJ, Werb Z, Mostov KE. Bryant DM, et al. Among authors: overeem aw. Dev Cell. 2014 Oct 27;31(2):171-87. doi: 10.1016/j.devcel.2014.08.027. Epub 2014 Oct 9. Dev Cell. 2014. PMID: 25307480 Free PMC article.

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