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321 results

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The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease.
Nanto-Hara F, Kanemitsu Y, Fukuda S, Kikuchi K, Asaji K, Saigusa D, Iwasaki T, Ho HJ, Mishima E, Suzuki T, Suzuki C, Tsukimi T, Matsuhashi T, Oikawa Y, Akiyama Y, Kure S, Owada Y, Tomioka Y, Soga T, Ito S, Abe T. Nanto-Hara F, et al. Among authors: owada y. Nephrol Dial Transplant. 2020 Feb 1;35(2):250-264. doi: 10.1093/ndt/gfz126. Nephrol Dial Transplant. 2020. PMID: 31411705
Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases.
Matsuhashi T, Sato T, Kanno SI, Suzuki T, Matsuo A, Oba Y, Kikusato M, Ogasawara E, Kudo T, Suzuki K, Ohara O, Shimbo H, Nanto F, Yamaguchi H, Saigusa D, Mukaiyama Y, Watabe A, Kikuchi K, Shima H, Mishima E, Akiyama Y, Oikawa Y, Hsin-Jung HO, Akiyama Y, Suzuki C, Uematsu M, Ogata M, Kumagai N, Toyomizu M, Hozawa A, Mano N, Owada Y, Aiba S, Yanagisawa T, Tomioka Y, Kure S, Ito S, Nakada K, Hayashi KI, Osaka H, Abe T. Matsuhashi T, et al. Among authors: owada y. EBioMedicine. 2017 Jun;20:27-38. doi: 10.1016/j.ebiom.2017.05.016. Epub 2017 May 13. EBioMedicine. 2017. PMID: 28579242 Free PMC article.
Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease.
Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaguchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T. Kikuchi K, et al. Among authors: owada y. Nat Commun. 2019 Apr 23;10(1):1835. doi: 10.1038/s41467-019-09735-4. Nat Commun. 2019. PMID: 31015435 Free PMC article.
Mitochondrial dysfunction in GnRH neurons impaired GnRH production.
Kagawa Y, Umaru BA, Shil SK, Hayasaka K, Zama R, Kobayashi Y, Miyazaki H, Kobayashi S, Suzuki C, Katori Y, Abe T, Owada Y. Kagawa Y, et al. Among authors: owada y. Biochem Biophys Res Commun. 2020 Sep 10;530(1):329-335. doi: 10.1016/j.bbrc.2020.07.090. Epub 2020 Aug 7. Biochem Biophys Res Commun. 2020. PMID: 32828307
Ndufs4 ablation decreases synaptophysin expression in hippocampus.
Shil SK, Kagawa Y, Umaru BA, Nanto-Hara F, Miyazaki H, Yamamoto Y, Kobayashi S, Suzuki C, Abe T, Owada Y. Shil SK, et al. Among authors: owada y. Sci Rep. 2021 May 26;11(1):10969. doi: 10.1038/s41598-021-90127-4. Sci Rep. 2021. PMID: 34040028 Free PMC article.
SGLT-1-specific inhibition ameliorates renal failure and alters the gut microbial community in mice with adenine-induced renal failure.
Ho HJ, Kikuchi K, Oikawa D, Watanabe S, Kanemitsu Y, Saigusa D, Kujirai R, Ikeda-Ohtsubo W, Ichijo M, Akiyama Y, Aoki Y, Mishima E, Ogata Y, Oikawa Y, Matsuhashi T, Toyohara T, Suzuki C, Suzuki T, Mano N, Kagawa Y, Owada Y, Katayama T, Nakayama T, Tomioka Y, Abe T. Ho HJ, et al. Among authors: owada y. Physiol Rep. 2021 Dec;9(24):e15092. doi: 10.14814/phy2.15092. Physiol Rep. 2021. PMID: 34921520 Free PMC article.
All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling.
Saito A, Sugawara A, Uruno A, Kudo M, Kagechika H, Sato Y, Owada Y, Kondo H, Sato M, Kurabayashi M, Imaizumi M, Tsuchiya S, Ito S. Saito A, et al. Among authors: owada y. Endocrinology. 2007 Mar;148(3):1412-23. doi: 10.1210/en.2006-0900. Epub 2006 Dec 14. Endocrinology. 2007. PMID: 17170094
A genome-wide association study identifies RNF213 as the first Moyamoya disease gene.
Kamada F, Aoki Y, Narisawa A, Abe Y, Komatsuzaki S, Kikuchi A, Kanno J, Niihori T, Ono M, Ishii N, Owada Y, Fujimura M, Mashimo Y, Suzuki Y, Hata A, Tsuchiya S, Tominaga T, Matsubara Y, Kure S. Kamada F, et al. Among authors: owada y. J Hum Genet. 2011 Jan;56(1):34-40. doi: 10.1038/jhg.2010.132. Epub 2010 Nov 4. J Hum Genet. 2011. PMID: 21048783
321 results