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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1926 1
1970 2
1972 3
1974 1
1976 2
1977 1
1978 2
1979 1
1980 5
1981 3
1982 2
1983 2
1984 4
1985 1
1987 2
1988 1
1989 1
1991 1
1992 1
1994 1
1996 1
1998 1
1999 1
2000 1
2001 4
2003 1
2005 1
2006 3
2007 4
2008 2
2009 7
2010 10
2011 14
2012 7
2013 7
2014 6
2015 11
2016 9
2017 10
2018 8
2019 6
2020 3
2021 12
2022 13
2023 11
2024 12
2025 12
2026 0

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192 results

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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.
A single nuclear transcriptomic characterisation of mechanisms responsible for impaired angiogenesis and blood-brain barrier function in Alzheimer's disease.
Tsartsalis S, Sleven H, Fancy N, Wessely F, Smith AM, Willumsen N, Cheung TKD, Rokicki MJ, Chau V, Ifie E, Khozoie C, Ansorge O, Yang X, Jenkyns MH, Davey K, McGarry A, Muirhead RCJ, Debette S, Jackson JS, Montagne A, Owen DR, Miners JS, Love S, Webber C, Cader MZ, Matthews PM. Tsartsalis S, et al. Among authors: owen dr. Nat Commun. 2024 Mar 12;15(1):2243. doi: 10.1038/s41467-024-46630-z. Nat Commun. 2024. PMID: 38472200 Free PMC article.
Imaging of atherosclerosis.
Owen DR, Lindsay AC, Choudhury RP, Fayad ZA. Owen DR, et al. Annu Rev Med. 2011;62:25-40. doi: 10.1146/annurev-med-041709-133809. Annu Rev Med. 2011. PMID: 21226610 Free PMC article. Review.
Protein-ligand data at scale to support machine learning.
Edwards AM, Owen DR; Structural Genomics Consortium Target 2035 Working Group. Edwards AM, et al. Among authors: owen dr. Nat Rev Chem. 2025 Sep;9(9):634-645. doi: 10.1038/s41570-025-00737-z. Epub 2025 Jul 23. Nat Rev Chem. 2025. PMID: 40702244 Review.
A data science roadmap for open science organizations engaged in early-stage drug discovery.
Edfeldt K, Edwards AM, Engkvist O, Günther J, Hartley M, Hulcoop DG, Leach AR, Marsden BD, Menge A, Misquitta L, Müller S, Owen DR, Schütt KT, Skelton N, Steffen A, Tropsha A, Vernet E, Wang Y, Wellnitz J, Willson TM, Clevert DA, Haibe-Kains B, Schiavone LH, Schapira M. Edfeldt K, et al. Among authors: owen dr. Nat Commun. 2024 Jul 5;15(1):5640. doi: 10.1038/s41467-024-49777-x. Nat Commun. 2024. PMID: 38965235 Free PMC article. Review.
Thrombocytopenia, anasarca, and severe inflammation.
Montazeripouragha A, Campbell CM, Russell J, Medvedev N, Owen DR, Harris A, Donnellan F, McCormick I, Fajgenbaum DC, Chen LYC. Montazeripouragha A, et al. Among authors: owen dr. Am J Hematol. 2022 Oct;97(10):1374-1380. doi: 10.1002/ajh.26651. Epub 2022 Jul 19. Am J Hematol. 2022. PMID: 35794839 Free PMC article. No abstract available.
Target 2035 - an update on private sector contributions.
Ackloo S, Antolin AA, Bartolome JM, Beck H, Bullock A, Betz UAK, Böttcher J, Brown PJ, Chaturvedi M, Crisp A, Daniels D, Dreher J, Edfeldt K, Edwards AM, Egner U, Elkins J, Fischer C, Glendorf T, Goldberg S, Hartung IV, Hillisch A, Homan E, Knapp S, Köster M, Krämer O, Llaveria J, Lessel U, Lindemann S, Linderoth L, Matsui H, Michel M, Montel F, Mueller-Fahrnow A, Müller S, Owen DR, Saikatendu KS, Santhakumar V, Sanderson W, Scholten C, Schapira M, Sharma S, Shireman B, Sundström M, Todd MH, Tredup C, Venable J, Willson TM, Arrowsmith CH. Ackloo S, et al. Among authors: owen dr. RSC Med Chem. 2023 Mar 16;14(6):1002-1011. doi: 10.1039/d2md00441k. eCollection 2023 Jun 22. RSC Med Chem. 2023. PMID: 37360399 Free PMC article.
Phagocytosis in the Brain: Homeostasis and Disease.
Galloway DA, Phillips AEM, Owen DRJ, Moore CS. Galloway DA, et al. Among authors: owen drj. Front Immunol. 2019 Apr 16;10:790. doi: 10.3389/fimmu.2019.00790. eCollection 2019. Front Immunol. 2019. PMID: 31040847 Free PMC article. Review.
PET imaging of neuroinflammation in neurological disorders.
Kreisl WC, Kim MJ, Coughlin JM, Henter ID, Owen DR, Innis RB. Kreisl WC, et al. Among authors: owen dr. Lancet Neurol. 2020 Nov;19(11):940-950. doi: 10.1016/S1474-4422(20)30346-X. Lancet Neurol. 2020. PMID: 33098803 Free PMC article. Review.
192 results