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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 3
1982 1
1983 2
1984 2
1985 2
1986 1
1989 1
1990 2
1992 1
1993 2
1996 1
1997 2
1999 1
2000 4
2001 1
2004 3
2005 4
2008 1
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2019 1
2026 0

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36 results

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Page 1
Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase.
Yu R, Kim Y, Maltseva N, Braunstein P, Joachimiak A, Hedstrom L. Yu R, et al. Chem Res Toxicol. 2019 Mar 18;32(3):456-466. doi: 10.1021/acs.chemrestox.8b00342. Epub 2019 Feb 25. Chem Res Toxicol. 2019. PMID: 30746940 Free PMC article.
In contrast, the effects of RNS damaged metabolites are less appreciated. 5-Amino-3-beta-(d-ribofuranosyl)-3 H-imidazo-[4,5- d][1,3]oxazine-7-one (oxanosine) and its nucleotides are products of guanosine nitrosation. Here we demonstrate that oxanosine monophosphate …
In contrast, the effects of RNS damaged metabolites are less appreciated. 5-Amino-3-beta-(d-ribofuranosyl)-3 H-imidazo-[4,5- d][1,3]oxazine- …
Oxanosine, a novel nucleoside from actinomycetes.
Shimada N, Yagisawa N, Naganawa H, Takita T, Hamada M, Takeuchi T, Umezawa H. Shimada N, et al. J Antibiot (Tokyo). 1981 Sep;34(9):1216-8. doi: 10.7164/antibiotics.34.1216. J Antibiot (Tokyo). 1981. PMID: 7328060 Free article. No abstract available.
Cleavage of deoxyoxanosine-containing oligodeoxyribonucleotides by bacterial endonuclease V.
Hitchcock TM, Gao H, Cao W. Hitchcock TM, et al. Nucleic Acids Res. 2004 Aug 2;32(13):4071-80. doi: 10.1093/nar/gkh747. Print 2004. Nucleic Acids Res. 2004. PMID: 15289580 Free PMC article.
All four oxanosine-containing base pairs (A/O, T/O, C/O and G/O) were cleaved with similar efficiency. ...Single-stranded oxanosine-containing DNA was cleaved with a lower efficiency as compared with double-stranded oxanosine-containing DNA. ...
All four oxanosine-containing base pairs (A/O, T/O, C/O and G/O) were cleaved with similar efficiency. ...Single-stranded oxanosin …
Oxanosine is a substrate of adenosine deaminase. Implications for the quest for a toxicological marker for nitrosation activity.
Majumdar P, Wu H, Tipton P, Glaser R. Majumdar P, et al. Chem Res Toxicol. 2005 Dec;18(12):1830-41. doi: 10.1021/tx050232h. Chem Res Toxicol. 2005. PMID: 16359173
Oxanosine became relevant in toxicology in 1996 with the discovery that it is formed in nitrosative guanosine deamination. As part of studies of the mechanism of oxanosine formation, the synthesis was attempted of [7- 18O]oxanosine by enzymatic 16O/18O-exchan …
Oxanosine became relevant in toxicology in 1996 with the discovery that it is formed in nitrosative guanosine deamination. As part of …
Mode of action of oxanosine, a novel nucleoside antibiotic.
Yagisawa N, Shimada N, Takita T, Ishizuka M, Takeuchi T, Umezawa H. Yagisawa N, et al. J Antibiot (Tokyo). 1982 Jun;35(6):755-9. doi: 10.7164/antibiotics.35.755. J Antibiot (Tokyo). 1982. PMID: 6288649 Free article.
Oxanosine, a novel nucleoside, inhibits the growth of Escherichia coli K-12 on peptone agar, but not on Nutrient agar. ...The growth of leukemia L 1210 cell was also inhibited by oxanosine, and the inhibition was reversed by guanylic acid. Oxanosine was confi …
Oxanosine, a novel nucleoside, inhibits the growth of Escherichia coli K-12 on peptone agar, but not on Nutrient agar. ...The growth …
Oxanosine, a novel nucleoside from actinomycetes.
Yagisawa N, Shimada N, Naganawa H, Takita T, Hamada M, Takeuchi T, Umezawa H, Nakamura H, Iitaka Y. Yagisawa N, et al. Nucleic Acids Symp Ser. 1981;(10):55-8. Nucleic Acids Symp Ser. 1981. PMID: 7031611
Oxanosine, a novel nucleoside, has been isolated from the culture filtrate of a strain of Streptomyces. ...The primary action of oxanosine appears to be inhibition of GMP-synthetase. Intravenous injection of 4 mg of oxanosine to mice does not show any toxic s …
Oxanosine, a novel nucleoside, has been isolated from the culture filtrate of a strain of Streptomyces. ...The primary action of o …
The X-ray structure determination of oxanosine.
Nakamura H, Yagisawa N, Shimada N, Takita T, Umezawa H, Iitaka Y. Nakamura H, et al. J Antibiot (Tokyo). 1981 Sep;34(9):1219-21. doi: 10.7164/antibiotics.34.1219. J Antibiot (Tokyo). 1981. PMID: 7328061 Free article. No abstract available.
Synergistic anti-viral effect of oxanosine and ddI against human immunodeficiency virus.
Nakamura M, Ogawa T, Yokono A, Nakamori S, Ohno T, Umezawa K. Nakamura M, et al. Biomed Pharmacother. 2005 Jan-Feb;59(1-2):47-50. doi: 10.1016/j.biopha.2004.05.017. Epub 2005 Jan 26. Biomed Pharmacother. 2005. PMID: 15740935
The combined effect against human immunodeficiency virus (HIV) of oxanosine and 2'3'-dideoxyinosine (ddI) has been evaluated by the production of viral particles, the expression of viral antigens on cell surfaces, and the amount of viral genome integrated in the host cells …
The combined effect against human immunodeficiency virus (HIV) of oxanosine and 2'3'-dideoxyinosine (ddI) has been evaluated by the p …
Induction by the guanosine analogue oxanosine of reversion toward the normal phenotype of K-ras-transformed rat kidney cells.
Itoh O, Kuroiwa S, Atsumi S, Umezawa K, Takeuchi T, Hori M. Itoh O, et al. Cancer Res. 1989 Feb 15;49(4):996-1000. Cancer Res. 1989. PMID: 2643467
Oxanosine, a guanosine analogue antibiotic, altered the "transformed" morphology of rat kidney cells integrating a temperature-sensitive K-ras gene into "normal" morphology at 34 degrees C, a permissive temperature. ...These changes in p21 were the same as those which occu …
Oxanosine, a guanosine analogue antibiotic, altered the "transformed" morphology of rat kidney cells integrating a temperature-sensit …
36 results