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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
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1926 2
1928 1
1932 2
1933 1
1937 1
1938 1
1941 1
1944 1
1945 10
1946 16
1947 12
1948 5
1949 6
1950 3
1951 3
1952 5
1953 8
1954 7
1955 6
1956 10
1957 12
1958 15
1959 15
1960 32
1961 53
1962 21
1963 29
1964 30
1965 48
1966 80
1967 83
1968 88
1969 112
1970 124
1971 111
1972 109
1973 140
1974 136
1975 196
1976 159
1977 149
1978 189
1979 203
1980 210
1981 224
1982 255
1983 352
1984 481
1985 491
1986 517
1987 530
1988 553
1989 632
1990 615
1991 692
1992 679
1993 701
1994 832
1995 819
1996 791
1997 835
1998 831
1999 879
2000 945
2001 993
2002 1091
2003 1150
2004 1373
2005 1576
2006 1755
2007 1947
2008 2005
2009 2186
2010 2532
2011 2737
2012 2887
2013 3315
2014 3464
2015 3774
2016 3752
2017 3917
2018 4193
2019 4634
2020 4964
2021 4985
2022 4898
2023 4640
2024 5195
2025 6062
2026 2183

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85,897 results

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Page 1
Oxygen toxicity from plants to people.
Schloss JV. Schloss JV. Planta. 2002 Nov;216(1):38-43. doi: 10.1007/s00425-002-0905-3. Epub 2002 Nov 12. Planta. 2002. PMID: 12430012 Review.
Over the past 30 years, acute oxygen toxicity in plants, mammals and enteric bacteria has been defined in terms of specific interactions of oxygen with a limited number of molecular targets. At least in the case of plants and mammals, response at the level of …
Over the past 30 years, acute oxygen toxicity in plants, mammals and enteric bacteria has been defined in terms of specific in …
The use of cobalt chloride as a chemical hypoxia model.
Muñoz-Sánchez J, Chánez-Cárdenas ME. Muñoz-Sánchez J, et al. J Appl Toxicol. 2019 Apr;39(4):556-570. doi: 10.1002/jat.3749. Epub 2018 Nov 28. J Appl Toxicol. 2019. PMID: 30484873 Review.
The use of hypoxia models in cell culture has allowed the characterization of the hypoxia response at the cellular, biochemical and molecular levels. Although a decrease in oxygen concentration is the optimal hypoxia model, the problem faced by many researchers is a …
The use of hypoxia models in cell culture has allowed the characterization of the hypoxia response at the cellular, biochemical and m …
High dissolved oxygen exacerbates ammonia toxicity with sex-dependent manner in zebrafish.
Sun SX, Hu CT, Qiao F, Chen LQ, Zhang ML, Du ZY. Sun SX, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2023 Apr;266:109549. doi: 10.1016/j.cbpc.2023.109549. Epub 2023 Jan 20. Comp Biochem Physiol C Toxicol Pharmacol. 2023. PMID: 36690240
Ammonia nitrogen is one of the important environmental factors, and causes negative effects for fish health in ecosystem and aquaculture. The toxic effects and mechanisms of ammonia in fish deserve further investigation. In the present study, we exposed female and male zeb …
Ammonia nitrogen is one of the important environmental factors, and causes negative effects for fish health in ecosystem and aquaculture. Th …
Extracorporeal blood oxygenation and ozonation: clinical and biological implications of ozone therapy.
Di Paolo N, Gaggiotti E, Galli F. Di Paolo N, et al. Redox Rep. 2005;10(3):121-30. doi: 10.1179/135100005X38888. Redox Rep. 2005. PMID: 16156950 Free article. Review.
On the bases of these underlying principles and against often prejudicial scepticism and concerns about its toxicity, ozone has been used in autohemotherapy (AHT) for four decades with encouraging results. ...Latterly, a new and more effective therapeutic approach to ozone …
On the bases of these underlying principles and against often prejudicial scepticism and concerns about its toxicity, ozone has been …
A multiwell plate-based system for toxicity screening under multiple static or cycling oxygen environments.
Yao M, Walker G, Gamcsik MP. Yao M, et al. Sci Rep. 2021 Feb 17;11(1):4020. doi: 10.1038/s41598-021-83579-1. Sci Rep. 2021. PMID: 33597640 Free PMC article.
The principle behind the design is presented and the response of human pancreatic cancer PANC-1 cells treated with tirapazamine and doxorubicin under eight different static or cycling oxygen levels was measured. As expected, tirapazamine is progressively more toxic …
The principle behind the design is presented and the response of human pancreatic cancer PANC-1 cells treated with tirapazamine and doxorubi …
Oxygen sensing and metabolic homeostasis.
Palmer BF, Clegg DJ. Palmer BF, et al. Mol Cell Endocrinol. 2014 Nov;397(1-2):51-8. doi: 10.1016/j.mce.2014.08.001. Epub 2014 Aug 15. Mol Cell Endocrinol. 2014. PMID: 25132648 Review.
Oxygen-sensing mechanisms have evolved to maintain cell and tissue homeostasis since the ability to sense and respond to changes in oxygen is essential for survival. ...Chronic hypoxia activates cellular sensing mechanisms which lead to protein synthesis desi …
Oxygen-sensing mechanisms have evolved to maintain cell and tissue homeostasis since the ability to sense and respond to chang …
Oxygen: the poison is in the dose.
Winslow RM. Winslow RM. Transfusion. 2013 Feb;53(2):424-37. doi: 10.1111/j.1537-2995.2012.03774.x. Epub 2012 Jul 15. Transfusion. 2013. PMID: 22804568 Review.
Cell-free hemoglobin (Hb) has been blamed for a spectrum of problems, including vasoconstriction pancreatitis, myocardial infarction, and pulmonary hypertension in hemolytic anemia, malaria, and sickle cell anemia, and from Hb-based oxygen carriers (HBOCs). . …
Cell-free hemoglobin (Hb) has been blamed for a spectrum of problems, including vasoconstriction pancreatitis, myocardial infarction, …
Turning the Oxygen Dial: Balancing the Highs and Lows.
Baik AH, Jain IH. Baik AH, et al. Trends Cell Biol. 2020 Jul;30(7):516-536. doi: 10.1016/j.tcb.2020.04.005. Epub 2020 May 5. Trends Cell Biol. 2020. PMID: 32386878 Free PMC article. Review.
Oxygen is both vital and toxic to life. Molecular oxygen is the most used substrate in the human body and is required for several hundred diverse biochemical reactions. ...In this review, we describe cellular and organismal mechanisms of oxygen sensing …
Oxygen is both vital and toxic to life. Molecular oxygen is the most used substrate in the human body and is required f …
Life with oxygen.
Semenza GL. Semenza GL. Science. 2007 Oct 5;318(5847):62-4. doi: 10.1126/science.1147949. Science. 2007. PMID: 17916722
The survival of all metazoan organisms is dependent on the regulation of O2 delivery and utilization to maintain a balance between the generation of energy and production of potentially toxic oxidants. Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that funct …
The survival of all metazoan organisms is dependent on the regulation of O2 delivery and utilization to maintain a balance between the gener …
Benefits and risks of oxygen therapy during acute medical illness: Just a matter of dose!
Allardet-Servent J, Sicard G, Metz V, Chiche L. Allardet-Servent J, et al. Rev Med Interne. 2019 Oct;40(10):670-676. doi: 10.1016/j.revmed.2019.04.003. Epub 2019 May 1. Rev Med Interne. 2019. PMID: 31054779 Review.
Although oxygen is known to be toxic at high inspired oxygen fractions, a recent meta-analysis of RCTs revealed the life-threatening effect of hyperoxemia, with a dose-dependent relationship. ...High-flow oxygen should only be used in a few diseases su …
Although oxygen is known to be toxic at high inspired oxygen fractions, a recent meta-analysis of RCTs revealed the lif …
85,897 results
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