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Page 1
A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation.
Moncunill-Massaguer C, Saura-Esteller J, Pérez-Perarnau A, Palmeri CM, Núñez-Vázquez S, Cosialls AM, González-Gironès DM, Pomares H, Korwitz A, Preciado S, Albericio F, Lavilla R, Pons G, Langer T, Iglesias-Serret D, Gil J. Moncunill-Massaguer C, et al. Among authors: perez perarnau a. Oncotarget. 2015 Dec 8;6(39):41750-65. doi: 10.18632/oncotarget.6154. Oncotarget. 2015. PMID: 26497683 Free PMC article.
A trifluorinated thiazoline scaffold leading to pro-apoptotic agents targeting prohibitins.
Pérez-Perarnau A, Preciado S, Palmeri CM, Moncunill-Massaguer C, Iglesias-Serret D, González-Gironès DM, Miguel M, Karasawa S, Sakamoto S, Cosialls AM, Rubio-Patiño C, Saura-Esteller J, Ramón R, Caja L, Fabregat I, Pons G, Handa H, Albericio F, Gil J, Lavilla R. Pérez-Perarnau A, et al. Angew Chem Int Ed Engl. 2014 Sep 15;53(38):10150-4. doi: 10.1002/anie.201405758. Epub 2014 Sep 5. Angew Chem Int Ed Engl. 2014. PMID: 25196378
Glycogen synthase kinase-3β is involved in ligand-dependent activation of transcription and cellular localization of the glucocorticoid receptor.
Rubio-Patiño C, Palmeri CM, Pérez-Perarnau A, Cosialls AM, Moncunill-Massaguer C, González-Gironès DM, Pons-Hernández L, López JM, Ventura F, Gil J, Pons G, Iglesias-Serret D. Rubio-Patiño C, et al. Among authors: perez perarnau a. Mol Endocrinol. 2012 Sep;26(9):1508-20. doi: 10.1210/me.2011-1366. Epub 2012 Jul 6. Mol Endocrinol. 2012. PMID: 22771494 Free PMC article.
Isoform-selective phosphoinositide 3-kinase inhibitors induce apoptosis in chronic lymphocytic leukaemia cells.
de Frias M, Iglesias-Serret D, Cosialls AM, González-Gironès DM, Pérez-Perarnau A, Rubio-Patiño C, Rückle T, Camps M, de Sevilla AF, de la Banda E, Pons G, Gil J. de Frias M, et al. Among authors: perez perarnau a. Br J Haematol. 2010 Jul;150(1):108-11. doi: 10.1111/j.1365-2141.2010.08151.x. Epub 2010 Mar 11. Br J Haematol. 2010. PMID: 20230409 No abstract available.