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Page 1
Did you mean p mikkila[Author] (74 results)?
NTHL1 is a recessive cancer susceptibility gene.
Nurmi AK, Pelttari LM, Kiiski JI, Khan S, Nurmikolu M, Suvanto M, Aho N, Tasmuth T, Kalso E, Schleutker J, Kallioniemi A, Heikkilä P; FinnGen; Aittomäki K, Blomqvist C, Nevanlinna H. Nurmi AK, et al. Among authors: heikkila p. Sci Rep. 2023 Nov 30;13(1):21127. doi: 10.1038/s41598-023-47441-w. Sci Rep. 2023. PMID: 38036545 Free PMC article.
None of the variants associated significantly with cancer risk in the primary BC series; however, in the FinnGen data, NTHL1 c.244C>T p.(Gln82Ter) associated with BC with a high risk for homozygous (OR = 44.7 [95% CI 6.90-290], P = 6.7 10(-5)) and a low risk for …
None of the variants associated significantly with cancer risk in the primary BC series; however, in the FinnGen data, NTHL1 c.244C>T …
Deep learning quantification reveals a fundamental prognostic role for ductular reaction in biliary atresia.
Nyholm I, Sjöblom N, Pihlajoki M, Hukkinen M, Lohi J, Heikkilä P, Mutka A, Jahnukainen T, Davenport M, Heikinheimo M, Arola J, Pakarinen MP. Nyholm I, et al. Among authors: heikkila p. Hepatol Commun. 2023 Dec 1;7(12):e0333. doi: 10.1097/HC9.0000000000000333. eCollection 2023 Dec 1. Hepatol Commun. 2023. PMID: 38051554 Free PMC article.
After KPE, patients with subsequent liver transplantation or death showed an increase in DR% (7.9%-9.9%, p = 0.04) and PIH% (1.6%-2.4%, p = 0.009), whereas patients with native liver survival (NLS) showed decreasing BE% (5.5%-3.0%, p = 0.03) and persistently …
After KPE, patients with subsequent liver transplantation or death showed an increase in DR% (7.9%-9.9%, p = 0.04) and PIH% (1.6%-2.4 …
Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial.
Assessment of the Safety and Efficacy of a New Thrombolytic (ASSENT-2) Investigators; Van De Werf F, Adgey J, Ardissino D, Armstrong PW, Aylward P, Barbash G, Betriu A, Binbrek AS, Califf R, Diaz R, Fanebust R, Fox K, Granger C, Heikkilä J, Husted S, Jansky P, Langer A, Lupi E, Maseri A, Meyer J, Mlczoch J, Mocceti D, Myburgh D, Oto A, Paolasso E, Pehrsson K, Seabra-Gomes R, Soares-Piegas L, Sùgrue D, Tendera M, Topol E, Toutouzas P, Vahanian A, Verheugt F, Wallentin L, White H. Assessment of the Safety and Efficacy of a New Thrombolytic (ASSENT-2) Investigators, et al. Among authors: heikkila j. Lancet. 1999 Aug 28;354(9180):716-22. doi: 10.1016/s0140-6736(99)07403-6. Lancet. 1999. PMID: 10475182 Clinical Trial.
Rates of intracranial haemorrhage were similar (0.93% for tenecteplase and 0.94% for alteplase), but fewer non-cerebral bleeding complications (26.43 vs 28.95%, p=0.0003) and less need for blood transfusion (4.25 vs 5.49%, p=0.0002) were seen with tenecteplase. ...
Rates of intracranial haemorrhage were similar (0.93% for tenecteplase and 0.94% for alteplase), but fewer non-cerebral bleeding complicatio …
Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study.
Sipilä PN, Lindbohm JV, Batty GD, Heikkilä N, Vahtera J, Suominen S, Väänänen A, Koskinen A, Nyberg ST, Meri S, Pentti J, Warren-Gash C, Hayward AC, Kivimäki M. Sipilä PN, et al. Among authors: heikkila n. Circulation. 2023 May 23;147(21):1582-1593. doi: 10.1161/CIRCULATIONAHA.122.061183. Epub 2023 Mar 27. Circulation. 2023. PMID: 36971007 Free article.
Superconducting spintronic tunnel diode.
Strambini E, Spies M, Ligato N, Ilić S, Rouco M, González-Orellana C, Ilyn M, Rogero C, Bergeret FS, Moodera JS, Virtanen P, Heikkilä TT, Giazotto F. Strambini E, et al. Among authors: heikkila tt. Nat Commun. 2022 May 4;13(1):2431. doi: 10.1038/s41467-022-29990-2. Nat Commun. 2022. PMID: 35508475 Free PMC article.
With the help of an analytical theoretical model we can link the maximum rectification to the spin polarization (P) of the barrier and describe the quasi-ideal Shockley-diode behavior of the junction. ...
With the help of an analytical theoretical model we can link the maximum rectification to the spin polarization (P) of the barrier an …
Serum FGF19 predicts outcomes of Kasai portoenterostomy in biliary atresia.
Nyholm I, Hukkinen M, Pihlajoki M, Davidson JR, Tyraskis A, Lohi J, Heikkilä P, Hänninen S, Andersson N, Eloranta K, Carpén O, Heikinheimo M, Davenport M, Pakarinen MP. Nyholm I, et al. Among authors: heikkila p. Hepatology. 2023 Apr 1;77(4):1263-1273. doi: 10.1097/HEP.0000000000000048. Epub 2023 Jan 3. Hepatology. 2023. PMID: 36692476 Free PMC article.
Patients with unsuccessful KPE (419 vs. 145 pg/mL, p =0.047), and those subsequently underwent liver transplantation (410 vs. 99 pg/mL, p =0.007) had significantly increased serum, but not liver, FGF19, which localized mainly in hepatocytes. In Cox hazard modeling s …
Patients with unsuccessful KPE (419 vs. 145 pg/mL, p =0.047), and those subsequently underwent liver transplantation (410 vs. 99 pg/m …
Coronary collateral circulation.
Pellinen TJ, Virtanen KS, Toivonen L, Heikkilä J, Hekali P, Frick MH. Pellinen TJ, et al. Among authors: heikkila j. Clin Cardiol. 1991 Feb;14(2):111-8. doi: 10.1002/clc.4960140206. Clin Cardiol. 1991. PMID: 2044240 Free article.
The highest prevalence of collaterals occurred in stenosis of the right coronary artery (60%), followed by the left descending artery (45%); they occurred least in the left circumflex artery (21%) (p less than 0.001). The frequency of intra-arterial collateral circulation …
The highest prevalence of collaterals occurred in stenosis of the right coronary artery (60%), followed by the left descending artery (45%); …
Reproducibility and predictive value of scoring stromal tumour infiltrating lymphocytes in triple-negative breast cancer: a multi-institutional study.
O'Loughlin M, Andreu X, Bianchi S, Chemielik E, Cordoba A, Cserni G, Figueiredo P, Floris G, Foschini MP, Heikkilä P, Kulka J, Liepniece-Karele I, Regitnig P, Reiner A, Ryska A, Sapino A, Shalaby A, Stovgaard ES, Quinn C, Walsh EM, Zolota V, Glynn SA, Callagy G. O'Loughlin M, et al. Among authors: heikkila p. Breast Cancer Res Treat. 2018 Aug;171(1):1-9. doi: 10.1007/s10549-018-4825-8. Epub 2018 May 17. Breast Cancer Res Treat. 2018. PMID: 29774470

RESULTS: Moderate agreement was achieved for absolute sTILs scores (intraclass correlation coefficient (ICC) = 0.683, 95% CI 0.601-0.767, p-value < 0.001). Agreement was less when a 25% threshold was used (ICC 0.509, 95% CI 0.416-0.614, p-value < 0.001) and fo

RESULTS: Moderate agreement was achieved for absolute sTILs scores (intraclass correlation coefficient (ICC) = 0.683, 95% CI 0.601-0.767, …
Controlling oleogel crystallization using ultrasonic standing waves.
Valoppi F, Salmi A, Ratilainen M, Barba L, Puranen T, Tommiska O, Helander P, Heikkilä J, Haeggström E. Valoppi F, et al. Among authors: heikkila j. Sci Rep. 2020 Sep 2;10(1):14448. doi: 10.1038/s41598-020-71177-6. Sci Rep. 2020. PMID: 32879336 Free PMC article.
Low and high serum IgG associates with respiratory infections in a young and working age population.
Holma P, Pesonen P, Karjalainen MK, Järvelin MR, Väyrynen S, Sliz E, Heikkilä A, Seppänen MRJ, Kettunen J, Auvinen J, Hautala T. Holma P, et al. Among authors: heikkila a. EBioMedicine. 2023 Aug;94:104712. doi: 10.1016/j.ebiom.2023.104712. Epub 2023 Jul 13. EBioMedicine. 2023. PMID: 37453363 Free PMC article.
Low IgG was associated with antibiotic use (relative risk 1.285, 95% CI 1.001-1.648; p = 0.049) and sinus surgery (relative risk 2.257, 95% CI 1.163-4.379; p = 0.016). High serum IgG was associated with at least one pneumonia episode (relative risk 1.737, 95% CI 1.0 …
Low IgG was associated with antibiotic use (relative risk 1.285, 95% CI 1.001-1.648; p = 0.049) and sinus surgery (relative risk 2.25 …
718 results