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70 results

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Page 1
The ongoing Streptococcus pyogenes (Group A Streptococcus) outbreak in London, United Kingdom, in December 2022: a molecular epidemiology study.
Alcolea-Medina A, Snell LB, Alder C, Charalampous T, Williams TGS; Synnovis Microbiology Laboratory Group; Tan MKI, Al-Yaakoubi N, Humayun G, Newsholme W, Goldenberg S, Nebbia G, Neil SJD, Batra R, Edgeworth JD. Alcolea-Medina A, et al. Among authors: newsholme w. Clin Microbiol Infect. 2023 Jul;29(7):887-890. doi: 10.1016/j.cmi.2023.03.001. Epub 2023 Mar 15. Clin Microbiol Infect. 2023. PMID: 36925107 Free PMC article.
By multivariable analysis of pathogen-related factors, spea (OR 8.9, CI 1.4-57, p 0.020) and spej (OR 12, CI 1.8-78, p 0.011) were associated with invasive disease. ...
By multivariable analysis of pathogen-related factors, spea (OR 8.9, CI 1.4-57, p 0.020) and spej (OR 12, CI 1.8-78, p 0.011) …
The impact of cholecalciferol supplementation on the systemic inflammatory profile: a systematic review and meta-analysis of high-quality randomized controlled trials.
Calton EK, Keane KN, Newsholme P, Zhao Y, Soares MJ. Calton EK, et al. Among authors: newsholme p. Eur J Clin Nutr. 2017 Aug;71(8):931-943. doi: 10.1038/ejcn.2017.67. Epub 2017 May 10. Eur J Clin Nutr. 2017. PMID: 28488684 Review.
Studies employing a low dose (<1000 IU/d) showed increased CRP (WMD=0.615, (0.132, 1.098), P=0.013). In contrast, 1000 IU/d had a favourable effect on CRP (WMD=-0.939, (-1.805, -0.073), P=0.034) but heterogeneity was significant (I(2)=61.3%, P=0.017). Meta …
Studies employing a low dose (<1000 IU/d) showed increased CRP (WMD=0.615, (0.132, 1.098), P=0.013). In contrast, 1000 IU/d had a …
The role of tryptophan in fatigue in different conditions of stress.
Castell LM, Yamamoto T, Phoenix J, Newsholme EA. Castell LM, et al. Among authors: newsholme ea. Adv Exp Med Biol. 1999;467:697-704. doi: 10.1007/978-1-4615-4709-9_90. Adv Exp Med Biol. 1999. PMID: 10721121 Review.

In the CFS patients, the pre-exercise concentration of plasma free tryptophan was higher than in controls (p < 0.05) but did not change during or after exercise. This might indicate an abnormally high level of brain 5-HT in CFS patients leading to persistent fatigue. In

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In the CFS patients, the pre-exercise concentration of plasma free tryptophan was higher than in controls (p < 0.05) but did not c

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The effect of cigarette smoking, alcohol consumption and fruit and vegetable consumption on IVF outcomes: a review and presentation of original data.
Firns S, Cruzat VF, Keane KN, Joesbury KA, Lee AH, Newsholme P, Yovich JL. Firns S, et al. Among authors: newsholme p. Reprod Biol Endocrinol. 2015 Dec 16;13:134. doi: 10.1186/s12958-015-0133-x. Reprod Biol Endocrinol. 2015. PMID: 26669322 Free PMC article. Review.

Of significance, it was found that male smoking caused an increased risk of pregnancy loss (p = 0.029), while female smoking caused an adverse effect on ovarian reserve. Both alcohol consumption (beta = 0.074, p < 0.001) and fruit and vegetable consumption (beta

…
Of significance, it was found that male smoking caused an increased risk of pregnancy loss (p = 0.029), while female smoking caused a …
Reduction in Clostridium difficile environmental contamination by hospitalized patients treated with fidaxomicin.
Biswas JS, Patel A, Otter JA, Wade P, Newsholme W, van Kleef E, Goldenberg SD. Biswas JS, et al. Among authors: newsholme w. J Hosp Infect. 2015 Jul;90(3):267-70. doi: 10.1016/j.jhin.2015.01.015. Epub 2015 Feb 9. J Hosp Infect. 2015. PMID: 25728208 Free article. Clinical Trial.
Patients treated with fidaxomicin were less likely to contaminate their environment (25/68, 36.8%) than patients treated with metronidazole and/or vancomycin (38/66 57.6%) (P = 0.02). Treatment with fidaxomicin was associated with reduced environmental contamination with C …
Patients treated with fidaxomicin were less likely to contaminate their environment (25/68, 36.8%) than patients treated with metronidazole …
Insulin resistance, cognition and Alzheimer's disease biomarkers: Evidence that CSF Aβ42 moderates the association between insulin resistance and increased CSF tau levels.
Woodfield A, Porter T, Gilani I, Noordin S, Li QX, Collins S, Martins RN, Maruff P, Masters CL, Rowe CC, Villemagne VL, Dore V, Newsholme P, Laws SM, Verdile G; AIBL Research Group. Woodfield A, et al. Among authors: newsholme p. Neurobiol Aging. 2022 Jun;114:38-48. doi: 10.1016/j.neurobiolaging.2022.03.004. Epub 2022 Mar 11. Neurobiol Aging. 2022. PMID: 35381406
Now, we aimed to determine if CSF total (t-tau) or phosphorylated tau (p-tau) mediated the relationship between HOMA-IR and cognition, and explore sex or amyloid-beta (Abeta) biomarkers as moderators of this relationship. ...
Now, we aimed to determine if CSF total (t-tau) or phosphorylated tau (p-tau) mediated the relationship between HOMA-IR and cognition …
70 results