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Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies.
Dachicourt N, Serradas P, Bailbé D, Kergoat M, Doaré L, Portha B. Dachicourt N, et al. Among authors: serradas p. J Endocrinol. 1997 Nov;155(2):369-76. doi: 10.1677/joe.0.1550369. J Endocrinol. 1997. PMID: 9415071

An infusion of GLP-1 (10 ng/min per kg; i.v.) in n0-STZ rats enhanced significantly (P < 0.01) basal plasma insulin levels, and, when combined with an i.v. glucose tolerance and insulin secretion test, it was found to improve (P < 0.05) glucose tolerance and t

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An infusion of GLP-1 (10 ng/min per kg; i.v.) in n0-STZ rats enhanced significantly (P < 0.01) basal plasma insulin levels, and, w

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Evaluation of the pancreatic B-cell function in the rat after prenatal exposure to streptozotocin or N-nitrosomethylurea.
Serradas P, Giroix MH, Portha B. Serradas P, et al. Diabete Metab. 1989 Jan-Feb;15(1):30-7. Diabete Metab. 1989. PMID: 2524413
This alteration was maintained: in 2 month-old offspring a mild hyperglycemia (9.9 +/- 0.3 vs 8.5 +/- 0.2 mM in control rats, p less than 0.01), a decrease of the pancreatic insulin stores (by 45%) and an impaired insulin secretion in response to glucose and arginine was o …
This alteration was maintained: in 2 month-old offspring a mild hyperglycemia (9.9 +/- 0.3 vs 8.5 +/- 0.2 mM in control rats, p less …