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Blood myeloid dendritic cells from HIV-1-infected individuals display a proapoptotic profile characterized by decreased Bcl-2 levels and by caspase-3+ frequencies that are associated with levels of plasma viremia and T cell activation in an exploratory study.
Dillon SM, Friedlander LJ, Rogers LM, Meditz AL, Folkvord JM, Connick E, McCarter MD, Wilson CC. Dillon SM, et al. J Virol. 2011 Jan;85(1):397-409. doi: 10.1128/JVI.01118-10. Epub 2010 Oct 20. J Virol. 2011. PMID: 20962079 Free PMC article.
Immunophenotypic alterations in acute and early HIV infection.
Al-Harthi L, MaWhinney S, Connick E, Schooley RT, Forster JE, Benson C, Thompson M, Judson F, Palella F, Landay A. Al-Harthi L, et al. Clin Immunol. 2007 Dec;125(3):299-308. doi: 10.1016/j.clim.2007.08.011. Epub 2007 Oct 3. Clin Immunol. 2007. PMID: 17916441 Free PMC article. Clinical Trial.
The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals.
Hogan CM, Degruttola V, Sun X, Fiscus SA, Del Rio C, Hare CB, Markowitz M, Connick E, Macatangay B, Tashima KT, Kallungal B, Camp R, Morton T, Daar ES, Little S; A5217 Study Team. Hogan CM, et al. J Infect Dis. 2012 Jan 1;205(1):87-96. doi: 10.1093/infdis/jir699. Epub 2011 Dec 15. J Infect Dis. 2012. PMID: 22180621 Free PMC article. Clinical Trial.