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Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives.

Humbert M, Guignabert C, Bonnet S, Dorfmüller P, Klinger JR, Nicolls MR, Olschewski AJ, Pullamsetti SS, Schermuly RT, Stenmark KR, Rabinovitch M. Humbert M, et al. Eur Respir J. 2019 Jan 24;53(1):1801887. doi: 10.1183/13993003.01887-2018. Print 2019 Jan. Eur Respir J. 2019. PMID: 30545970 Free PMC article. Review.

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Lymphatic Dysfunction, Leukotrienes, and Lymphedema.

Jiang X, Nicolls MR, Tian W, Rockson SG. Jiang X, et al. Annu Rev Physiol. 2018 Feb 10;80:49-70. doi: 10.1146/annurev-physiol-022516-034008. Epub 2017 Oct 13. Annu Rev Physiol. 2018. PMID: 29029593 Free PMC article. Review.

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Pulmonary vascular remodeling in pulmonary hypertension.

Tuder RM. Tuder RM. Cell Tissue Res. 2017 Mar;367(3):643-649. doi: 10.1007/s00441-016-2539-y. Epub 2016 Dec 26. Cell Tissue Res. 2017. PMID: 28025704 Free PMC article. Review.

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Sex-derived attributes contributing to SARS-CoV-2 mortality.

Chanana N, Palmo T, Sharma K, Kumar R, Graham BB, Pasha Q. Chanana N, et al. Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E562-E567. doi: 10.1152/ajpendo.00295.2020. Epub 2020 Jul 29. Am J Physiol Endocrinol Metab. 2020. PMID: 32726128 Free PMC article. Review.

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Contribution of metabolic reprogramming to macrophage plasticity and function.

El Kasmi KC, Stenmark KR. El Kasmi KC, et al. Semin Immunol. 2015 Aug;27(4):267-75. doi: 10.1016/j.smim.2015.09.001. Epub 2015 Oct 9. Semin Immunol. 2015. PMID: 26454572 Free PMC article. Review.

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MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension.

Deng L, Blanco FJ, Stevens H, Lu R, Caudrillier A, McBride M, McClure JD, Grant J, Thomas M, Frid M, Stenmark K, White K, Seto AG, Morrell NW, Bradshaw AC, MacLean MR, Baker AH. Deng L, et al. Circ Res. 2015 Oct 23;117(10):870-883. doi: 10.1161/CIRCRESAHA.115.306806. Epub 2015 Aug 26. Circ Res. 2015. PMID: 26311719 Free PMC article.

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Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.

Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KR. Frid MG, et al. Am J Respir Crit Care Med. 2020 Jan 15;201(2):224-239. doi: 10.1164/rccm.201903-0591OC. Am J Respir Crit Care Med. 2020. PMID: 31545648 Free PMC article.

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Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension.

Hu CJ, Poth JM, Zhang H, Flockton A, Laux A, Kumar S, McKeon B, Mouradian G, Li M, Riddle S, Pugliese SC, Brown RD, Wallace EM, Graham BB, Frid MG, Stenmark KR. Hu CJ, et al. Eur Respir J. 2019 Dec 12;54(6):1900378. doi: 10.1183/13993003.00378-2019. Print 2019 Dec. Eur Respir J. 2019. PMID: 31515405 Free PMC article.

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An Optimized Evans Blue Protocol to Assess Vascular Leak in the Mouse.

Wick MJ, Harral JW, Loomis ZL, Dempsey EC. Wick MJ, et al. J Vis Exp. 2018 Sep 12;(139):57037. doi: 10.3791/57037. J Vis Exp. 2018. PMID: 30272649 Free PMC article.

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Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.

Zhang H, Wang D, Li M, Plecitá-Hlavatá L, D'Alessandro A, Tauber J, Riddle S, Kumar S, Flockton A, McKeon BA, Frid MG, Reisz JA, Caruso P, El Kasmi KC, Ježek P, Morrell NW, Hu CJ, Stenmark KR. Zhang H, et al. Circulation. 2017 Dec 19;136(25):2468-2485. doi: 10.1161/CIRCULATIONAHA.117.028069. Epub 2017 Sep 26. Circulation. 2017. PMID: 28972001 Free PMC article.

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