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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 6
1988 10
1989 8
1990 11
1991 6
1992 6
1993 9
1994 5
1995 8
1996 2
1997 2
1998 2
1999 6
2000 2
2001 2
2002 4
2003 4
2004 6
2005 5
2006 4
2007 3
2008 5
2009 2
2010 5
2011 7
2012 3
2013 3
2014 4
2015 3
2016 1
2020 0
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Article attribute
Article type
Publication date

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144 results
Results by year
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Page 1
In vivo genome editing using Staphylococcus aureus Cas9.
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. Ran FA, et al. Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1. Nature. 2015. PMID: 25830891 Free PMC article.
CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. Xue W, et al. Nature. 2014 Oct 16;514(7522):380-4. doi: 10.1038/nature13589. Epub 2014 Aug 6. Nature. 2014. PMID: 25119044 Free PMC article.
c-Myc regulates transcriptional pause release.
Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, Burge CB, Sharp PA, Young RA. Rahl PB, et al. Cell. 2010 Apr 30;141(3):432-45. doi: 10.1016/j.cell.2010.03.030. Cell. 2010. PMID: 20434984 Free PMC article.
Lentivirus-delivered stable gene silencing by RNAi in primary cells.
Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. Stewart SA, et al. RNA. 2003 Apr;9(4):493-501. doi: 10.1261/rna.2192803. RNA. 2003. PMID: 12649500 Free PMC article.
Histone H3K27ac separates active from poised enhancers and predicts developmental state.
Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Creyghton MP, et al. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21931-6. doi: 10.1073/pnas.1016071107. Epub 2010 Nov 24. Proc Natl Acad Sci U S A. 2010. PMID: 21106759 Free PMC article.
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Wu X, et al. Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752079 Free PMC article.
MicroRNA functions in stress responses.
Leung AK, Sharp PA. Leung AK, et al. Mol Cell. 2010 Oct 22;40(2):205-15. doi: 10.1016/j.molcel.2010.09.027. Mol Cell. 2010. PMID: 20965416 Free PMC article. Review.
The role of miRNAs in regulating gene expression networks.
Gurtan AM, Sharp PA. Gurtan AM, et al. J Mol Biol. 2013 Oct 9;425(19):3582-600. doi: 10.1016/j.jmb.2013.03.007. Epub 2013 Mar 13. J Mol Biol. 2013. PMID: 23500488 Free PMC article. Review.
Life and death decisions by the E2F transcription factors.
Iaquinta PJ, Lees JA. Iaquinta PJ, et al. Curr Opin Cell Biol. 2007 Dec;19(6):649-57. doi: 10.1016/j.ceb.2007.10.006. Epub 2007 Nov 26. Curr Opin Cell Biol. 2007. PMID: 18032011 Free PMC article. Review.
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