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2018 1
2019 35
2020 21
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Page 1
LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL.
Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, Verdun RE, Lossos IS. Parvin S, et al. Cancer Cell. 2019 Sep 16;36(3):237-249.e6. doi: 10.1016/j.ccell.2019.07.007. Epub 2019 Aug 22. Cancer Cell. 2019. PMID: 31447348
Tumor-targeted silencing of the peptide transporter TAP induces potent antitumor immunity.
Garrido G, Schrand B, Rabasa A, Levay A, D'Eramo F, Berezhnoy A, Modi S, Gefen T, Marijt K, Doorduijn E, Dudeja V, van Hall T, Gilboa E. Garrido G, et al. Nat Commun. 2019 Aug 21;10(1):3773. doi: 10.1038/s41467-019-11728-2. Nat Commun. 2019. PMID: 31434881 Free PMC article.
Activation of STAT3 signaling is mediated by TFF1 silencing in gastric neoplasia.
Soutto M, Chen Z, Bhat AA, Wang L, Zhu S, Gomaa A, Bates A, Bhat NS, Peng D, Belkhiri A, Piazuelo MB, Washington MK, Steven XC, Peek R Jr, El-Rifai W. Soutto M, et al. Nat Commun. 2019 Jul 10;10(1):3039. doi: 10.1038/s41467-019-11011-4. Nat Commun. 2019. PMID: 31292446 Free PMC article.
Phase 2 study of pembrolizumab and circulating biomarkers to predict anticancer response in advanced, unresectable hepatocellular carcinoma.
Feun LG, Li YY, Wu C, Wangpaichitr M, Jones PD, Richman SP, Madrazo B, Kwon D, Garcia-Buitrago M, Martin P, Hosein PJ, Savaraj N. Feun LG, et al. Cancer. 2019 Oct 15;125(20):3603-3614. doi: 10.1002/cncr.32339. Epub 2019 Jun 28. Cancer. 2019. PMID: 31251403 Clinical Trial.
TAF1 plays a critical role in AML1-ETO driven leukemogenesis.
Xu Y, Man N, Karl D, Martinez C, Liu F, Sun J, Martinez CJ, Martin GM, Beckedorff F, Lai F, Yue J, Roisman A, Greenblatt S, Duffort S, Wang L, Sun X, Figueroa M, Shiekhattar R, Nimer S. Xu Y, et al. Nat Commun. 2019 Oct 29;10(1):4925. doi: 10.1038/s41467-019-12735-z. Nat Commun. 2019. PMID: 31664040 Free PMC article.
Genomic evolution of uveal melanoma arising in ocular melanocytosis.
Durante MA, Field MG, Sanchez MI, Covington KR, Decatur CL, Dubovy SR, Harbour JW. Durante MA, et al. Cold Spring Harb Mol Case Stud. 2019 Aug 1;5(4):a004051. doi: 10.1101/mcs.a004051. Print 2019 Aug. Cold Spring Harb Mol Case Stud. 2019. PMID: 31186267 Free PMC article.
Morphine tolerance is attenuated in germfree mice and reversed by probiotics, implicating the role of gut microbiome.
Zhang L, Meng J, Ban Y, Jalodia R, Chupikova I, Fernandez I, Brito N, Sharma U, Abreu MT, Ramakrishnan S, Roy S. Zhang L, et al. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13523-13532. doi: 10.1073/pnas.1901182116. Epub 2019 Jun 17. Proc Natl Acad Sci U S A. 2019. PMID: 31209039 Free PMC article.
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