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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2001 1
2002 1
2003 1
2004 2
2006 2
2007 5
2008 18
2009 24
2010 52
2011 78
2012 98
2013 68
2014 90
2015 47
2016 45
2017 39
2018 26
2019 11
2020 7
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Search Results

498 results
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Page 1
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.
Camacho-Pereira J, Tarragó MG, Chini CCS, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN. Camacho-Pereira J, et al. Cell Metab. 2016 Jun 14;23(6):1127-1139. doi: 10.1016/j.cmet.2016.05.006. Cell Metab. 2016. PMID: 27304511 Free PMC article.
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Baker DJ, Wijshake T, Tchkonia T, LeBrasseur NK, Childs BG, van de Sluis B, Kirkland JL, van Deursen JM. Baker DJ, et al. Nature. 2011 Nov 2;479(7372):232-6. doi: 10.1038/nature10600. Nature. 2011. PMID: 22048312 Free PMC article.
Molecular pathology endpoints useful for aging studies.
Niedernhofer LJ, Kirkland JL, Ladiges W. Niedernhofer LJ, et al. Ageing Res Rev. 2017 May;35:241-249. doi: 10.1016/j.arr.2016.09.012. Epub 2016 Oct 6. Ageing Res Rev. 2017. PMID: 27721062 Free PMC article. Review.
Breaking fat: The regulation and mechanisms of lipophagy.
Schulze RJ, Sathyanarayan A, Mashek DG. Schulze RJ, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1178-1187. doi: 10.1016/j.bbalip.2017.06.008. Epub 2017 Jun 20. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28642194 Free PMC article. Review.
mTOR regulation of autophagy.
Jung CH, Ro SH, Cao J, Otto NM, Kim DH. Jung CH, et al. FEBS Lett. 2010 Apr 2;584(7):1287-95. doi: 10.1016/j.febslet.2010.01.017. Epub 2010 Jan 18. FEBS Lett. 2010. PMID: 20083114 Free PMC article. Review.
Aging and adipose tissue: potential interventions for diabetes and regenerative medicine.
Palmer AK, Kirkland JL. Palmer AK, et al. Exp Gerontol. 2016 Dec 15;86:97-105. doi: 10.1016/j.exger.2016.02.013. Epub 2016 Feb 26. Exp Gerontol. 2016. PMID: 26924669 Free PMC article. Review.
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Schafer MJ, White TA, Evans G, Tonne JM, Verzosa GC, Stout MB, Mazula DL, Palmer AK, Baker DJ, Jensen MD, Torbenson MS, Miller JD, Ikeda Y, Tchkonia T, van Deursen JM, Kirkland JL, LeBrasseur NK. Schafer MJ, et al. Diabetes. 2016 Jun;65(6):1606-15. doi: 10.2337/db15-0291. Epub 2016 Mar 16. Diabetes. 2016. PMID: 26983960 Free PMC article.
Targeting senescent cells enhances adipogenesis and metabolic function in old age.
Xu M, Palmer AK, Ding H, Weivoda MM, Pirtskhalava T, White TA, Sepe A, Johnson KO, Stout MB, Giorgadze N, Jensen MD, LeBrasseur NK, Tchkonia T, Kirkland JL. Xu M, et al. Elife. 2015 Dec 19;4:e12997. doi: 10.7554/eLife.12997. Elife. 2015. PMID: 26687007 Free PMC article.
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