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1

Inflammatory mechanisms linking obesity and metabolic disease.

Saltiel AR, Olefsky JM. Saltiel AR, et al. J Clin Invest. 2017 Jan 3;127(1):1-4. doi: 10.1172/JCI92035. Epub 2017 Jan 3. J Clin Invest. 2017. PMID: 28045402 Free PMC article. Review.

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2

An Integrated View of Immunometabolism.

Lee YS, Wollam J, Olefsky JM. Lee YS, et al. Cell. 2018 Jan 11;172(1-2):22-40. doi: 10.1016/j.cell.2017.12.025. Cell. 2018. PMID: 29328913 Free article. Review.

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3

Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications.

Goodarzi MO. Goodarzi MO. Lancet Diabetes Endocrinol. 2018 Mar;6(3):223-236. doi: 10.1016/S2213-8587(17)30200-0. Epub 2017 Sep 14. Lancet Diabetes Endocrinol. 2018. PMID: 28919064 Review.

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4

An environment-dependent transcriptional network specifies human microglia identity.

Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. Gosselin D, et al. Science. 2017 Jun 23;356(6344):eaal3222. doi: 10.1126/science.aal3222. Epub 2017 May 25. Science. 2017. PMID: 28546318 Free PMC article.

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5

Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training.

Roberts CK, Hevener AL, Barnard RJ. Roberts CK, et al. Compr Physiol. 2013 Jan;3(1):1-58. doi: 10.1002/cphy.c110062. Compr Physiol. 2013. PMID: 23720280 Free PMC article. Review.

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6

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P.

Kim JY, Garcia-Carbonell R, Yamachika S, Zhao P, Dhar D, Loomba R, Kaufman RJ, Saltiel AR, Karin M. Kim JY, et al. Cell. 2018 Sep 20;175(1):133-145.e15. doi: 10.1016/j.cell.2018.08.020. Epub 2018 Sep 13. Cell. 2018. PMID: 30220454 Free PMC article.

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7

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.

Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge JP, Coppola G, Khakh BS. Chai H, et al. Neuron. 2017 Aug 2;95(3):531-549.e9. doi: 10.1016/j.neuron.2017.06.029. Epub 2017 Jul 14. Neuron. 2017. PMID: 28712653 Free PMC article.

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8

Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?

Febbraio MA, Reibe S, Shalapour S, Ooi GJ, Watt MJ, Karin M. Febbraio MA, et al. Cell Metab. 2019 Jan 8;29(1):18-26. doi: 10.1016/j.cmet.2018.10.012. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449681 Free PMC article. Review.

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9

Modeling ALS with motor neurons derived from human induced pluripotent stem cells.

Sances S, Bruijn LI, Chandran S, Eggan K, Ho R, Klim JR, Livesey MR, Lowry E, Macklis JD, Rushton D, Sadegh C, Sareen D, Wichterle H, Zhang SC, Svendsen CN. Sances S, et al. Nat Neurosci. 2016 Apr;19(4):542-53. doi: 10.1038/nn.4273. Nat Neurosci. 2016. PMID: 27021939 Free PMC article. Review.

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10

TBK1 at the Crossroads of Inflammation and Energy Homeostasis in Adipose Tissue.

Zhao P, Wong KI, Sun X, Reilly SM, Uhm M, Liao Z, Skorobogatko Y, Saltiel AR. Zhao P, et al. Cell. 2018 Feb 8;172(4):731-743.e12. doi: 10.1016/j.cell.2018.01.007. Cell. 2018. PMID: 29425491 Free PMC article.

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