P30 GM110761/GM/NIGMS NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2014	3
2015	12
2016	23
2017	25
2018	16
2019	9
2020	11
2021	6
2022	3

1

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice.

Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. Rathnayake AD, et al. Sci Transl Med. 2020 Aug 19;12(557):eabc5332. doi: 10.1126/scitranslmed.abc5332. Epub 2020 Aug 3. Sci Transl Med. 2020. PMID: 32747425 Free PMC article.

2

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.

Alhammad YMO, Kashipathy MM, Roy A, Gagné JP, McDonald P, Gao P, Nonfoux L, Battaile KP, Johnson DK, Holmstrom ED, Poirier GG, Lovell S, Fehr AR. Alhammad YMO, et al. J Virol. 2021 Jan 13;95(3):e01969-20. doi: 10.1128/JVI.01969-20. Print 2021 Jan 13. J Virol. 2021. PMID: 33158944 Free PMC article.

3

Linking autoantigen properties to mechanisms of immunity.

Griffin JD, Song JY, Sestak JO, DeKosky BJ, Berkland CJ. Griffin JD, et al. Adv Drug Deliv Rev. 2020;165-166:105-116. doi: 10.1016/j.addr.2020.04.005. Epub 2020 Apr 20. Adv Drug Deliv Rev. 2020. PMID: 32325104 Free PMC article. Review.

4

Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.

Wiedmann M, Dranchak PK, Aitha M, Queme B, Collmus CD, Kashipathy MM, Kanter L, Lamy L, Rogers JM, Tao D, Battaile KP, Rai G, Lovell S, Suga H, Inglese J. Wiedmann M, et al. J Biol Chem. 2021 Jan-Jun;296:100628. doi: 10.1016/j.jbc.2021.100628. Epub 2021 Apr 1. J Biol Chem. 2021. PMID: 33812994 Free PMC article.

5

Exploring the conformations of nitric oxide synthase with fluorescence.

Arnett DC, Bailey SK, Johnson CK. Arnett DC, et al. Front Biosci (Landmark Ed). 2018 Jun 1;23(11):2133-2145. doi: 10.2741/4694. Front Biosci (Landmark Ed). 2018. PMID: 29772550 Free PMC article. Review.

6

Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors.

Chang KO, Kim Y, Lovell S, Rathnayake AD, Groutas WC. Chang KO, et al. Viruses. 2019 Feb 25;11(2):197. doi: 10.3390/v11020197. Viruses. 2019. PMID: 30823509 Free PMC article. Review.

7

Structural insights into the function of steroidogenic cytochrome P450 17A1.

Yadav R, Petrunak EM, Estrada DF, Scott EE. Yadav R, et al. Mol Cell Endocrinol. 2017 Feb 5;441:68-75. doi: 10.1016/j.mce.2016.08.035. Epub 2016 Aug 24. Mol Cell Endocrinol. 2017. PMID: 27566228 Free PMC article. Review.

8

Functionalized High Mannose-Specific Lectins for the Discovery of Type I Mannosidase Inhibitors.

Kurhade SE, Weiner JD, Gao FP, Farrell MP. Kurhade SE, et al. Angew Chem Int Ed Engl. 2021 May 25;60(22):12313-12318. doi: 10.1002/anie.202101249. Epub 2021 Apr 26. Angew Chem Int Ed Engl. 2021. PMID: 33728787 Free PMC article.

9

Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.

Rathnayake AD, Kim Y, Dampalla CS, Nguyen HN, Jesri AM, Kashipathy MM, Lushington GH, Battaile KP, Lovell S, Chang KO, Groutas WC. Rathnayake AD, et al. J Med Chem. 2020 Oct 22;63(20):11945-11963. doi: 10.1021/acs.jmedchem.0c01252. Epub 2020 Oct 2. J Med Chem. 2020. PMID: 32945669

10

Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies.

Dampalla CS, Rathnayake AD, Perera KD, Jesri AM, Nguyen HN, Miller MJ, Thurman HA, Zheng J, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Kim Y, Groutas WC, Chang KO. Dampalla CS, et al. J Med Chem. 2021 Dec 23;64(24):17846-17865. doi: 10.1021/acs.jmedchem.1c01037. Epub 2021 Dec 5. J Med Chem. 2021. PMID: 34865476 Free PMC article.

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