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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2012 33
2013 82
2014 96
2015 98
2016 133
2017 166
2018 141
2019 161
2020 141
2021 80
2022 53
2023 49
2024 2

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1,141 results

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Page 1
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Electric-field-stimulated protein mechanics.
Hekstra DR, White KI, Socolich MA, Henning RW, Šrajer V, Ranganathan R. Hekstra DR, et al. Nature. 2016 Dec 15;540(7633):400-405. doi: 10.1038/nature20571. Epub 2016 Dec 7. Nature. 2016. PMID: 27926732 Free PMC article.
Ancient plant-like terpene biosynthesis in corals.
Burkhardt I, de Rond T, Chen PY, Moore BS. Burkhardt I, et al. Nat Chem Biol. 2022 Jun;18(6):664-669. doi: 10.1038/s41589-022-01026-2. Epub 2022 May 23. Nat Chem Biol. 2022. PMID: 35606558 Free PMC article.
Strategies for sample delivery for femtosecond crystallography.
Martiel I, Müller-Werkmeister HM, Cohen AE. Martiel I, et al. Acta Crystallogr D Struct Biol. 2019 Feb 1;75(Pt 2):160-177. doi: 10.1107/S2059798318017953. Epub 2019 Feb 19. Acta Crystallogr D Struct Biol. 2019. PMID: 30821705 Free PMC article. Review.
Ultrafast structural changes direct the first molecular events of vision.
Gruhl T, Weinert T, Rodrigues MJ, Milne CJ, Ortolani G, Nass K, Nango E, Sen S, Johnson PJM, Cirelli C, Furrer A, Mous S, Skopintsev P, James D, Dworkowski F, Båth P, Kekilli D, Ozerov D, Tanaka R, Glover H, Bacellar C, Brünle S, Casadei CM, Diethelm AD, Gashi D, Gotthard G, Guixà-González R, Joti Y, Kabanova V, Knopp G, Lesca E, Ma P, Martiel I, Mühle J, Owada S, Pamula F, Sarabi D, Tejero O, Tsai CJ, Varma N, Wach A, Boutet S, Tono K, Nogly P, Deupi X, Iwata S, Neutze R, Standfuss J, Schertler G, Panneels V. Gruhl T, et al. Nature. 2023 Mar;615(7954):939-944. doi: 10.1038/s41586-023-05863-6. Epub 2023 Mar 22. Nature. 2023. PMID: 36949205 Free PMC article.
An Isolable Mononuclear Palladium(I) Amido Complex.
Liu J, Bollmeyer MM, Kim Y, Xiao D, MacMillan SN, Chen Q, Leng X, Kim SH, Zhao L, Lancaster KM, Deng L. Liu J, et al. J Am Chem Soc. 2021 Jul 21;143(28):10751-10759. doi: 10.1021/jacs.1c04965. Epub 2021 Jul 7. J Am Chem Soc. 2021. PMID: 34232039
Structural basis for SHOC2 modulation of RAS signalling.
Liau NPD, Johnson MC, Izadi S, Gerosa L, Hammel M, Bruning JM, Wendorff TJ, Phung W, Hymowitz SG, Sudhamsu J. Liau NPD, et al. Nature. 2022 Sep;609(7926):400-407. doi: 10.1038/s41586-022-04838-3. Epub 2022 Jun 29. Nature. 2022. PMID: 35768504 Free PMC article.
Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution.
Zhao F, Yuan M, Keating C, Shaabani N, Limbo O, Joyce C, Woehl J, Barman S, Burns A, Tran Q, Zhu X, Ricciardi M, Peng L, Smith J, Huang D, Briney B, Sok D, Nemazee D, Teijaro JR, Wilson IA, Burton DR, Jardine JG. Zhao F, et al. Sci Signal. 2023 Aug 15;16(798):eabk3516. doi: 10.1126/scisignal.abk3516. Epub 2023 Aug 15. Sci Signal. 2023. PMID: 37582161
1,141 results