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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2008 | 3 |
2009 | 2 |
2010 | 3 |
2024 | 0 |
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7 results
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Page 1
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.
Cancer Cell. 2010 Dec 14;18(6):683-95. doi: 10.1016/j.ccr.2010.11.023.
Cancer Cell. 2010.
PMID: 21156289
Free PMC article.
A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling.
Han MJ, Wang H, Beer LA, Tang HY, Herlyn M, Speicher DW.
Han MJ, et al.
Proteomics. 2010 Dec;10(24):4450-62. doi: 10.1002/pmic.200900549. Epub 2010 Nov 17.
Proteomics. 2010.
PMID: 21136598
Free PMC article.
Item in Clipboard
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, Shellooe R, Marimuthu A, Nguyen H, Zhang KY, Artis DR, Schlessinger J, Su F, Higgins B, Iyer R, D'Andrea K, Koehler A, Stumm M, Lin PS, Lee RJ, Grippo J, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, Chapman PB, Flaherty KT, Xu X, Nathanson KL, Nolop K.
Bollag G, et al.
Nature. 2010 Sep 30;467(7315):596-9. doi: 10.1038/nature09454.
Nature. 2010.
PMID: 20823850
Free PMC article.
Clinical Trial.
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Active Notch1 confers a transformed phenotype to primary human melanocytes.
Pinnix CC, Lee JT, Liu ZJ, McDaid R, Balint K, Beverly LJ, Brafford PA, Xiao M, Himes B, Zabierowski SE, Yashiro-Ohtani Y, Nathanson KL, Bengston A, Pollock PM, Weeraratna AT, Nickoloff BJ, Pear WS, Capobianco AJ, Herlyn M.
Pinnix CC, et al.
Cancer Res. 2009 Jul 1;69(13):5312-20. doi: 10.1158/0008-5472.CAN-08-3767. Epub 2009 Jun 23.
Cancer Res. 2009.
PMID: 19549918
Free PMC article.
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CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.
Smalley KS, Xiao M, Villanueva J, Nguyen TK, Flaherty KT, Letrero R, Van Belle P, Elder DE, Wang Y, Nathanson KL, Herlyn M.
Smalley KS, et al.
Oncogene. 2009 Jan 8;28(1):85-94. doi: 10.1038/onc.2008.362. Epub 2008 Sep 15.
Oncogene. 2009.
PMID: 18794803
Free PMC article.
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Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas.
Smalley KS, Lioni M, Dalla Palma M, Xiao M, Desai B, Egyhazi S, Hansson J, Wu H, King AJ, Van Belle P, Elder DE, Flaherty KT, Herlyn M, Nathanson KL.
Smalley KS, et al.
Mol Cancer Ther. 2008 Sep;7(9):2876-83. doi: 10.1158/1535-7163.MCT-08-0431.
Mol Cancer Ther. 2008.
PMID: 18790768
Free PMC article.
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Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Smalley KS, Contractor R, Nguyen TK, Xiao M, Edwards R, Muthusamy V, King AJ, Flaherty KT, Bosenberg M, Herlyn M, Nathanson KL.
Smalley KS, et al.
Cancer Res. 2008 Jul 15;68(14):5743-52. doi: 10.1158/0008-5472.CAN-08-0235.
Cancer Res. 2008.
PMID: 18632627
Free PMC article.
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