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Year Number of Results
1998 3
1999 1
2000 2
2001 3
2002 1
2003 2
2021 0
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12 results
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Page 1
Hsp90 as a therapeutic target in prostate cancer.
Solit DB, Scher HI, Rosen N. Solit DB, et al. Semin Oncol. 2003 Oct;30(5):709-16. doi: 10.1016/s0093-7754(03)00346-4. Semin Oncol. 2003. PMID: 14571418 Review.
Inhibition of heat shock protein 90 function down-regulates Akt kinase and sensitizes tumors to Taxol.
Solit DB, Basso AD, Olshen AB, Scher HI, Rosen N. Solit DB, et al. Cancer Res. 2003 May 1;63(9):2139-44. Cancer Res. 2003. PMID: 12727831 Free article.
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.
Moasser MM, Basso A, Averbuch SD, Rosen N. Moasser MM, et al. Cancer Res. 2001 Oct 1;61(19):7184-8. Cancer Res. 2001. PMID: 11585753 Free article.
Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones.
Moasser MM, Sepp-Lorenzino L, Kohl NE, Oliff A, Balog A, Su DS, Danishefsky SJ, Rosen N. Moasser MM, et al. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1369-74. doi: 10.1073/pnas.95.4.1369. Proc Natl Acad Sci U S A. 1998. PMID: 9465021 Free PMC article.
17-Allylamino-17-demethoxygeldanamycin induces the degradation of androgen receptor and HER-2/neu and inhibits the growth of prostate cancer xenografts.
Solit DB, Zheng FF, Drobnjak M, Münster PN, Higgins B, Verbel D, Heller G, Tong W, Cordon-Cardo C, Agus DB, Scher HI, Rosen N. Solit DB, et al. Clin Cancer Res. 2002 May;8(5):986-93. Clin Cancer Res. 2002. PMID: 12006510 Free article.
Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway.
Muise-Helmericks RC, Grimes HL, Bellacosa A, Malstrom SE, Tsichlis PN, Rosen N. Muise-Helmericks RC, et al. J Biol Chem. 1998 Nov 6;273(45):29864-72. doi: 10.1074/jbc.273.45.29864. J Biol Chem. 1998. PMID: 9792703 Free article.
The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells.
Munster PN, Troso-Sandoval T, Rosen N, Rifkind R, Marks PA, Richon VM. Munster PN, et al. Cancer Res. 2001 Dec 1;61(23):8492-7. Cancer Res. 2001. PMID: 11731433 Free article.
Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases.
Zheng FF, Kuduk SD, Chiosis G, Münster PN, Sepp-Lorenzino L, Danishefsky SJ, Rosen N. Zheng FF, et al. Cancer Res. 2000 Apr 15;60(8):2090-4. Cancer Res. 2000. PMID: 10786665 Free article.
Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.
Münster PN, Srethapakdi M, Moasser MM, Rosen N. Münster PN, et al. Cancer Res. 2001 Apr 1;61(7):2945-52. Cancer Res. 2001. PMID: 11306472 Free article.
Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest.
Moasser MM, Srethapakdi M, Sachar KS, Kraker AJ, Rosen N. Moasser MM, et al. Cancer Res. 1999 Dec 15;59(24):6145-52. Cancer Res. 1999. PMID: 10626805 Free article.
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