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Anomalies in the review process and interpretation of the evidence in the NICE guideline for chronic fatigue syndrome and myalgic encephalomyelitis.
White P, Abbey S, Angus B, Ball HA, Buchwald DS, Burness C, Carson AJ, Chalder T, Clauw DJ, Coebergh J, David AS, Dworetzky BA, Edwards MJ, Espay AJ, Etherington J, Fink P, Flottorp S, Garcin B, Garner P, Glasziou P, Hamilton W, Henningsen P, Hoeritzauer I, Husain M, Huys AML, Knoop H, Kroenke K, Lehn A, Levenson JL, Little P, Lloyd A, Madan I, van der Meer JWM, Miller A, Murphy M, Nazareth I, Perez DL, Phillips W, Reuber M, Rief W, Santhouse A, Serranova T, Sharpe M, Stanton B, Stewart DE, Stone J, Tinazzi M, Wade DT, Wessely SC, Wyller V, Zeman A. White P, et al. J Neurol Neurosurg Psychiatry. 2023 Dec;94(12):1056-1063. doi: 10.1136/jnnp-2022-330463. Epub 2023 Jul 10. J Neurol Neurosurg Psychiatry. 2023. PMID: 37434321 Review.
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a disabling long-term condition of unknown cause. The National Institute for Health and Care Excellence (NICE) published a guideline in 2021 that highlighted the seriousness of the condition, but …
Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is a disabling long-term condition of unknown cause. The Na …
Evidence-Based Care for People with Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.
Sharpe M, Chalder T, White PD. Sharpe M, et al. J Gen Intern Med. 2022 Feb;37(2):449-452. doi: 10.1007/s11606-021-07188-4. Epub 2021 Nov 17. J Gen Intern Med. 2022. PMID: 34791590 Free PMC article.
Chronic fatigue syndrome (CFS), sometimes referred to as myalgic encephalomyelitis (ME) and often as CFS/ME, is an illness characterized by disabling fatigue and other symptoms, typically worsened by activity. The main evidence-based treatments are reh …
Chronic fatigue syndrome (CFS), sometimes referred to as myalgic encephalomyelitis (ME) and often as CFS/ME, is an illn …
PACE-GATE: An alternative view on a study with a poor trial protocol.
Stouten B. Stouten B. J Health Psychol. 2017 Aug;22(9):1192-1197. doi: 10.1177/1359105317707531. Epub 2017 May 12. J Health Psychol. 2017. PMID: 28805525
The controversies surrounding the effectiveness of cognitive behavioural therapy and graded exercise therapy for chronic fatigue syndrome are explained using Cohen's d effect sizes rather than arbitrary thresholds for 'succe …
The controversies surrounding the effectiveness of cognitive behavioural therapy and graded exercise therapy …
The PACE trial: It's time to broaden perceptions and move on.
Petrie KJ, Weinman J. Petrie KJ, et al. J Health Psychol. 2017 Aug;22(9):1198-1200. doi: 10.1177/1359105317703789. Epub 2017 Apr 10. J Health Psychol. 2017. PMID: 28805523
The continued critiques of the PACE trial highlight how differing beliefs about the causes of chronic fatigue syndrome still influence how scientific studies in this area are accepted and evaluated. Causal beliefs about chronic fatigue …
The continued critiques of the PACE trial highlight how differing beliefs about the causes of chronic fatigue …
'PACE-Gate': When clinical trial evidence meets open data access.
Geraghty KJ. Geraghty KJ. J Health Psychol. 2017 Aug;22(9):1106-1112. doi: 10.1177/1359105316675213. Epub 2016 Nov 1. J Health Psychol. 2017. PMID: 27807258
Science is not always plain sailing and sometimes the voyage is across an angry sea. A recent clinical trial of treatments for chronic fatigue syndrome (the PACE trial) has whipped up a storm of controversy. Patients claim t …
Science is not always plain sailing and sometimes the voyage is across an angry sea. A recent clinical trial of treatments for …