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Did you mean dry skin regeneration (516 results)?
PDRN prevents SIRT1 degradation by attenuating autophagy during skin aging.
Chen J, Qiu F, Shi J, Huang W, Zhao C, Han Q. Chen J, et al. PLoS One. 2025 May 9;20(5):e0321005. doi: 10.1371/journal.pone.0321005. eCollection 2025. PLoS One. 2025. PMID: 40343916 Free PMC article.
Polydeoxyribonucleotide (PDRN) is a low molecular weight linear polyribonucleotide fragment derived from salmon sperm, known for its potential in tissue regeneration and anti-inflammatory applications. ...These results suggest that PDRN has potential as a the …
Polydeoxyribonucleotide (PDRN) is a low molecular weight linear polyribonucleotide fragment derived from salmon sperm, known for its …
Analysis of Skin Regeneration and Barrier-Improvement Efficacy of Polydeoxyribonucleotide Isolated from Panax Ginseng (C.A. Mey.) Adventitious Root.
Lee KS, Lee S, Wang H, Lee G, Kim S, Ryu YH, Chang NH, Kang YW. Lee KS, et al. Molecules. 2023 Oct 24;28(21):7240. doi: 10.3390/molecules28217240. Molecules. 2023. PMID: 37959659 Free PMC article.
Polydeoxyribonucleotide (PDRN) has the ability to regenerate skin cells and improve the skin barrier and wound healing. ...Furthermore, Panax PDRN can potentially be a new plant-derived PDRN (PhytoPDRN) that may be utilized in the treatme …
Polydeoxyribonucleotide (PDRN) has the ability to regenerate skin cells and improve the skin barrier and wound h …
Polydeoxyribonucleotide: A Promising Biological Platform to Accelerate Impaired Skin Wound Healing.
Galeano M, Pallio G, Irrera N, Mannino F, Bitto A, Altavilla D, Vaccaro M, Squadrito G, Arcoraci V, Colonna MR, Lauro R, Squadrito F. Galeano M, et al. Pharmaceuticals (Basel). 2021 Oct 29;14(11):1103. doi: 10.3390/ph14111103. Pharmaceuticals (Basel). 2021. PMID: 34832885 Free PMC article. Review.
In light of all these observations, the aim of this review is to provide a full overview of PDRN applications on skin regeneration. We reviewed papers published in the last 25 years on PubMed, inserting "polydeoxyribonucleotide and wound healing" as the main …
In light of all these observations, the aim of this review is to provide a full overview of PDRN applications on skin regen …
From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional Biomolecules.
Marques C, Porcello A, Cerrano M, Hadjab F, Chemali M, Lourenço K, Hadjab B, Raffoul W, Applegate LA, Laurent AE. Marques C, et al. Biomolecules. 2025 Jan 19;15(1):148. doi: 10.3390/biom15010148. Biomolecules. 2025. PMID: 39858543 Free PMC article. Review.
However, recent studies have expanded this range to encompass fragments as small as 1 kDa and as large as 10,000 kDa. Clinically, PDRN/PN formulations, commercially available in various galenic forms (gels, creams, serums, masks, and injectables), have demonstrated promisi …
However, recent studies have expanded this range to encompass fragments as small as 1 kDa and as large as 10,000 kDa. Clinically, PDRN …
Polydeoxyribonucleotide exerts opposing effects on ERK activity in human skin keratinocytes and fibroblasts.
Shin SM, Baek EJ, Kim KH, Kim KJ, Park EJ. Shin SM, et al. Mol Med Rep. 2023 Aug;28(2):148. doi: 10.3892/mmr.2023.13035. Epub 2023 Jun 23. Mol Med Rep. 2023. PMID: 37350391 Free PMC article.
The potential effects of PDRN on skin regeneration were investigated. Fibroblast and keratinocyte proliferation and migration were analyzed using the water-soluble tetrazolium-8 and wound healing assays. ...Overall, PDRN exerts a positive effect on …
The potential effects of PDRN on skin regeneration were investigated. Fibroblast and keratinocyte proliferation and mig …
Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy.
Liu Y, Hu W, Pei X, Zhu J, Meng H, Lyu Y, Qu Z. Liu Y, et al. Int J Biol Macromol. 2025 Sep;322(Pt 3):146984. doi: 10.1016/j.ijbiomac.2025.146984. Epub 2025 Aug 19. Int J Biol Macromol. 2025. PMID: 40840755
Regenerative medicine, with stem cells and tissue engineering as its core, is dedicated to the regeneration of skin and organs and the treatment of diseases. Polydeoxyribonucleic acid (PDRN) has been demonstrated to promote skin regeneration and …
Regenerative medicine, with stem cells and tissue engineering as its core, is dedicated to the regeneration of skin and organs …
First Report on Microbial-Derived Polydeoxyribonucleotide: A Sustainable and Enhanced Alternative to Salmon-Based Polydeoxyribonucleotide.
Chae D, Oh SW, Choi YS, Kang DJ, Park CW, Lee J, Seo WS. Chae D, et al. Curr Issues Mol Biol. 2025 Jan 9;47(1):41. doi: 10.3390/cimb47010041. Curr Issues Mol Biol. 2025. PMID: 39852156 Free PMC article.
Electrophoretic analysis revealed that L-PDRN consists of smaller DNA fragments (under 100 bp) compared to salmon-derived PDRN (200-800 bp), suggesting greater bioavailability and skin absorption. ...The novel approach of utilizing microbial-derived PDRN …
Electrophoretic analysis revealed that L-PDRN consists of smaller DNA fragments (under 100 bp) compared to salmon-derived PDRN …
Effects of polydeoxyribonucleotide derived from Gynostemma pentaphyllum callus on skin barrier function.
Kim E, Choi S, Jang J, Shin HY, Ahn K, Kim SJ, Seo HH, Lee JH, Moh SH. Kim E, et al. Biochem Biophys Res Commun. 2025 Aug 30;776:152180. doi: 10.1016/j.bbrc.2025.152180. Epub 2025 Jun 8. Biochem Biophys Res Commun. 2025. PMID: 40527178
GP was extracted using a plant-based method and tested on skin cells. The study aimed to determine whether GP enhances the skin barrier similarly to SP. ...Additionally, GP treatment significantly upregulated key skin barrier proteins, including FLG and IVL, …
GP was extracted using a plant-based method and tested on skin cells. The study aimed to determine whether GP enhances the skin …
Plasma-Engineered PDRN: Surface Charge Neutralization and Nanosizing Enhance Uptake and Regeneration Potential.
Park SJ, Lee DH, Yoon KB, Kim A, Jung CY, Kim ST, Brito S, Bin BH. Park SJ, et al. Pharmaceutics. 2025 Aug 30;17(9):1136. doi: 10.3390/pharmaceutics17091136. Pharmaceutics. 2025. PMID: 41012473 Free PMC article.
Background: Polydeoxyribonucleotide (PDRN) is increasingly used in dermatology and cosmetic applications owing to its regenerative and anti-aging properties. However, its topical use is limited by its high molecular weight and anionic charge, which restrict skin pen …
Background: Polydeoxyribonucleotide (PDRN) is increasingly used in dermatology and cosmetic applications owing to its regenerative an …
Polydeoxyribonucleotides (PDRNs) From Skin to Musculoskeletal Tissue Regeneration via Adenosine A(2A) Receptor Involvement.
Veronesi F, Dallari D, Sabbioni G, Carubbi C, Martini L, Fini M. Veronesi F, et al. J Cell Physiol. 2017 Sep;232(9):2299-2307. doi: 10.1002/jcp.25663. Epub 2017 Mar 3. J Cell Physiol. 2017. PMID: 27791262 Review.
Most preclinical and clinical studies on tissue regeneration with PDRNs focused on skin, and only few are about musculoskeletal tissues. Starting from an overview on skin regeneration studies, through the analysis of in vitro, in vivo, and clinical stu …
Most preclinical and clinical studies on tissue regeneration with PDRNs focused on skin, and only few are about musculoskeleta …
42 results