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145 results

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Page 1
Pulsed electromagnetic fields mediate sensory nerve regulation for bone formation in aging models.
Wang T, Liang Z, Wang C, Chen J, Ma Y, Chen S, Zhou D, Hong Z. Wang T, et al. Nat Commun. 2025 Sep 29;16(1):8223. doi: 10.1038/s41467-025-63703-9. Nat Commun. 2025. PMID: 41022817 Free PMC article.
Pulsed electromagnetic fields (PEMFs) enhance bone formation to combat osteoporosis, yet the mechanisms by which they promote bone health during aging remain unclear. This study shows PEMFs enhance new bone formation and innervation, promoting osteogenesis and reducing adi …
Pulsed electromagnetic fields (PEMFs) enhance bone formation to combat osteoporosis, yet the mechanisms by which they promote bone he …
Pulsed electromagnetic field ameliorates the progression of osteoarthritis via the Sirt1/NF-κB pathway.
Zhou S, Wen H, He X, Han X, Li H. Zhou S, et al. Arthritis Res Ther. 2025 Feb 14;27(1):33. doi: 10.1186/s13075-025-03492-0. Arthritis Res Ther. 2025. PMID: 39953605 Free PMC article.
However, PEMFs' anti-inflammatory effect on osteoarthritis (OA) and the potential mechanism has not been fully elucidated. METHODS: Human chondrocytes (C28/I2) were stimulated with interleukin (IL)-1beta with or without the treatment of PEMF. ...At the mechanism …
However, PEMFs' anti-inflammatory effect on osteoarthritis (OA) and the potential mechanism has not been fully elucidated. METHODS: H …
Pulsed electromagnetic fields treatment ameliorates cardiac function after myocardial infarction in mice and pigs.
Wang S, Pei G, Shen J, Fang Z, Chen T, Wang L, Cheng H, Li H, Pei H, Feng Q, Fan Q, He C, Fu C, Guo Y, Wei Q. Wang S, et al. J Adv Res. 2026 Feb;80:1139-1153. doi: 10.1016/j.jare.2025.04.019. Epub 2025 Apr 16. J Adv Res. 2026. PMID: 40250556 Free PMC article.
OBJECTIVES: To investigate the efficacy, safety, and mechanisms of PEMF for MI. METHODS: We established MI models in both mice and pigs and performed serial echocardiography and cardiac magnetic resonance follow-up to demonstrate the benefit of PEMF treatment …
OBJECTIVES: To investigate the efficacy, safety, and mechanisms of PEMF for MI. METHODS: We established MI models in both mice …
Pulsed Electromagnetic Field (PEMF) stimulation as an adjunct to exercise: a brief review.
Ghanbari Ghoshchi S, Petroni ML, Piras A, Marcora SM, Raffi M. Ghanbari Ghoshchi S, et al. Front Sports Act Living. 2024 Sep 9;6:1471087. doi: 10.3389/fspor.2024.1471087. eCollection 2024. Front Sports Act Living. 2024. PMID: 39355761 Free PMC article. Review.
PEMF therapy works by emitting low-frequency electromagnetic pulses, which penetrate deep into tissues and cells, enhancing cellular function and health. ...In this review, we explore the effects of PEMF on exercise and the underlying physiological …
PEMF therapy works by emitting low-frequency electromagnetic pulses, which penetrate deep into tissues and cells, enhancing …
Pulsed electromagnetic fields inhibit atherosclerosis by regulating pyroptosis through membrane tension-mediated mechanosensitive channels.
Cheng H, Zhang Q, Zhong W, Li H, Wang L, Wang S, He C, Fu C, Wei Q. Cheng H, et al. Signal Transduct Target Ther. 2025 Nov 28;10(1):388. doi: 10.1038/s41392-025-02479-2. Signal Transduct Target Ther. 2025. PMID: 41309549 Free PMC article.
This study utilized ApoE-/- mice, ApoE-/-NLRP3-/- knockout mice, human umbilical vein endothelial cells (HUVECs), human aortic endothelial cells (HAECs), and human plasma samples for experiments, revealing significant endothelial cell (EC) inflammation and pyroptosi …
This study utilized ApoE-/- mice, ApoE-/-NLRP3-/- knockout mice, human umbilical vein endothelial cells (HUVECs), human aortic endoth …
Hexokinase 2 Suppression Alleviates the Catabolic Properties in Osteoarthritis via HMGA2 and Contributes to Pulsed Electromagnetic Field-mediated Cartilage Protection.
Bao C, Zhu S, Pang D, Yang M, Huang J, Wang F, Hou Y, Wang X, Feng Y, Yang H, Jiang J, He J, He C. Bao C, et al. Int J Biol Sci. 2025 Jan 27;21(4):1459-1477. doi: 10.7150/ijbs.101597. eCollection 2025. Int J Biol Sci. 2025. PMID: 39990654 Free PMC article.
The key glycolytic enzyme Hexokinase 2 (HK2) is highly expressed in chondrocytes in OA; however, its role remains unclear. Pulsed electromagnetic field (PEMF) is commonly used for the treatment of OA. However, the role of PEMF in cartilage damage and the underlying …
The key glycolytic enzyme Hexokinase 2 (HK2) is highly expressed in chondrocytes in OA; however, its role remains unclear. Pulsed electromag …
A theoretical study of bone remodelling under PEMF at cellular level.
Wang Y, Qin QH. Wang Y, et al. Comput Methods Biomech Biomed Engin. 2012;15(8):885-97. doi: 10.1080/10255842.2011.565752. Epub 2011 May 27. Comput Methods Biomech Biomed Engin. 2012. PMID: 21604221
However, the underlying mechanism by which bone remodelling under PEMF is regulated remains poorly understood. In this paper, a mathematical model of bone cell population of bone remodelling under PEMF at cellular level is developed to address this iss …
However, the underlying mechanism by which bone remodelling under PEMF is regulated remains poorly understood. In this paper, …
Pulsed electromagnetic fields potentiate bone marrow mesenchymal stem cell chondrogenesis by regulating the Wnt/β-catenin signaling pathway.
Song K, Hu J, Yang M, Xia Y, He C, Yang Y, Zhu S. Song K, et al. J Transl Med. 2024 Aug 6;22(1):741. doi: 10.1186/s12967-024-05470-7. J Transl Med. 2024. PMID: 39107784 Free PMC article.
BACKGROUND: Pulsed electromagnetic fields (PEMFs) show promise as a treatment for knee osteoarthritis (KOA) by reducing inflammation and promoting chondrogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs). PURPOSE: To identify the efficacy window o …
BACKGROUND: Pulsed electromagnetic fields (PEMFs) show promise as a treatment for knee osteoarthritis (KOA) by reducing inflammation and pro …
Coupling of pulsed electromagnetic fields (PEMF) therapy to molecular grounds of the cell.
Funk RH. Funk RH. Am J Transl Res. 2018 May 15;10(5):1260-1272. eCollection 2018. Am J Transl Res. 2018. PMID: 29887943 Free PMC article. Review.
At first we start with the clinical outcome of PEMF therapy. Then, we look for possible triggers and an electromagnetic counterpart that is endogenously inherent in cell biology and in the tissues of interest. Finally, we want to investigate causal molecular and cellula …
At first we start with the clinical outcome of PEMF therapy. Then, we look for possible triggers and an electromagnetic counterpart t …
Extracorporeal Magnetotransduction Therapy as a New Form of Electromagnetic Wave Therapy: From Gene Upregulation to Accelerated Matrix Mineralization in Bone Healing.
Gerdesmeyer L, Tübel J, Obermeier A, Harrasser N, Glowalla C, von Eisenhart-Rothe R, Burgkart R. Gerdesmeyer L, et al. Biomedicines. 2024 Oct 7;12(10):2269. doi: 10.3390/biomedicines12102269. Biomedicines. 2024. PMID: 39457582 Free PMC article.
EMTT offers a higher oscillation frequency and magnetic field strength compared to traditional Pulsed Electromagnetic Field (PEMF) therapy, showing promise in enhancing fracture healing and non-union recovery. However, the mechanisms underlying these effects remain …
EMTT offers a higher oscillation frequency and magnetic field strength compared to traditional Pulsed Electromagnetic Field (PEMF) th …
145 results