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The following term was not found in PubMed: 0936700
Page 1
Identification and characterization of DNA endonucleases in Plasmodium falciparum 3D7 clone.
Jiang N, Tu Z, Zhang Y, Li J, Feng Y, Yang N, Sang X, Chen Q. Jiang N, et al. Malar J. 2018 Jun 18;17(1):232. doi: 10.1186/s12936-018-2388-0. Malar J. 2018. PMID: 29914511 Free PMC article.
BACKGROUND: Plasmodium falciparum is the most virulent parasite of the five Plasmodium species that cause human malaria, and biological analysis of the parasite is critical for the development of novel strategies for disease control. ...The seven DNA endonucl …
BACKGROUND: Plasmodium falciparum is the most virulent parasite of the five Plasmodium species that cause human malaria …
Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria.
Woolley SD, Marquart L, Woodford J, Chalon S, Moehrle JJ, McCarthy JS, Barber BE. Woolley SD, et al. Malar J. 2021 Dec 20;20(1):470. doi: 10.1186/s12936-021-04003-7. Malar J. 2021. PMID: 34930260 Free PMC article.
Induced blood stage malaria volunteer infection studies (IBSM-VIS) provide a unique opportunity to evaluate the haematological response to early Plasmodium falciparum and Plasmodium vivax infection. METHODS: This study was an analysis of the haemoglobin, red …
Induced blood stage malaria volunteer infection studies (IBSM-VIS) provide a unique opportunity to evaluate the haematological response to e …
Plasmodium falciparum DDX55 is a nucleocytoplasmic protein and a 3'-5' direction-specific DNA helicase.
Yasmin R, Kaur I, Tuteja R. Yasmin R, et al. Protoplasma. 2020 Jul;257(4):1049-1067. doi: 10.1007/s00709-020-01495-z. Epub 2020 Mar 3. Protoplasma. 2020. PMID: 32125511
Although artemisinin combination therapies (ACTs) are contributing to substantial decline in the worldwide malaria burden, it is becoming vulnerable by the emergence of artemisinin resistance in Plasmodium falciparum leading to clinical failure of ACTs in Southeast …
Although artemisinin combination therapies (ACTs) are contributing to substantial decline in the worldwide malaria burden, it is becoming vu …
The var3 genes of Plasmodium falciparum 3D7 strain are differentially expressed in infected erythrocytes.
Zhang Y, Jiang N, Chang Z, Wang H, Lu H, Wahlgren M, Chen Q. Zhang Y, et al. Parasite. 2014;21:19. doi: 10.1051/parasite/2014019. Epub 2014 Apr 24. Parasite. 2014. PMID: 24759654 Free PMC article.
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important virulence factor encoded by a family of 59 var genes, including 56 var genes plus 3 small var3 genes. ...Thus, the var3 genes of the P. falciparum 3D7 strain were differentia …
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important virulence factor encoded by a family of 59 var g …
Detection of Developmental Asexual Stage-Specific RNA Editing Events in Plasmodium falciparum 3D7 Malaria Parasite.
Azad MTA, Sugi T, Qulsum U, Kato K. Azad MTA, et al. Microorganisms. 2024 Jan 10;12(1):137. doi: 10.3390/microorganisms12010137. Microorganisms. 2024. PMID: 38257964 Free PMC article.
Transcriptional variation has been studied but post-transcriptional modification due to RNA editing has not been investigated in Plasmodium. We investigated developmental stage-specific RNA editing in selected genes in Plasmodium falciparum 3D7. ...In …
Transcriptional variation has been studied but post-transcriptional modification due to RNA editing has not been investigated in Plasmodi …
Fungal-derived methyldeoxaphomins target Plasmodium falciparum segregation through the inhibition of PfActin1.
Jiang T, Lee JW, Collins JE, Schaefer S, Chen D, Nardella F, Wendt K, Peramuna TG, Paes R, McLellan JL, Bhasin J, Durst GL, Hanson KK, Chakrabarti D, Cichewicz RH, Winzeler EA. Jiang T, et al. Proc Natl Acad Sci U S A. 2025 Feb 25;122(8):e2418871122. doi: 10.1073/pnas.2418871122. Epub 2025 Feb 18. Proc Natl Acad Sci U S A. 2025. PMID: 40138707 Free PMC article.
In vitro evolution and whole genome analysis in Plasmodium falciparum with the most potent member, NPDG-F (EC(50) of 550 nM in Dd2; 290 nM in 3D7), shows that parasite resistance to methyldeoxaphomins is strongly associated with mutations in PfActin1 (PF3D …
In vitro evolution and whole genome analysis in Plasmodium falciparum with the most potent member, NPDG-F (EC(50) of 550 nM in …
Characterization of Plasmodium falciparum prohibitins as novel targets to block infection in humans by impairing the growth and transmission of the parasite.
Saini M, Ngwa CJ, Marothia M, Verma P, Ahmad S, Kumari J, Anand S, Vandana V, Goyal B, Chakraborti S, Pandey KC, Garg S, Pati S, Ranganathan A, Pradel G, Singh S. Saini M, et al. Biochem Pharmacol. 2023 Jun;212:115567. doi: 10.1016/j.bcp.2023.115567. Epub 2023 Apr 22. Biochem Pharmacol. 2023. PMID: 37088154
Prohibitins (PHBs) are highly conserved pleiotropic proteins as they have been shown to mediate key cellular functions. Here, we characterize PHBs encoding putative genes ofPlasmodium falciparum by exploiting different orthologous models. We demonstrated that PfPHB1 …
Prohibitins (PHBs) are highly conserved pleiotropic proteins as they have been shown to mediate key cellular functions. Here, we characteriz …
Identifying Fast and Slow-Acting Antimalarial Compounds of Pandemic Response Box Against Blood-Stage Culture of Plasmodium falciparum 3D7.
Rajendran V, Naveen NC. Rajendran V, et al. Curr Microbiol. 2024 Jan 30;81(3):81. doi: 10.1007/s00284-023-03601-9. Curr Microbiol. 2024. PMID: 38289473
The evolving clinical resistance in Plasmodium falciparum and the spike in malarial cases after the COVID-19 outbreak has triggered a search for new antimalarials effective against multi-drug-resistant P. falciparum strains. In this study, we assessed the tim …
The evolving clinical resistance in Plasmodium falciparum and the spike in malarial cases after the COVID-19 outbreak has trig …
The structure of Plasmodium falciparum 3D7_0606800 reveals a bi-lobed architecture that supports re-annotation as a Venus Flytrap protein.
Parker ML, Ramaswamy R, van Gordon K, Powell CJ, Bosch J, Boulanger MJ. Parker ML, et al. Protein Sci. 2017 Sep;26(9):1878-1885. doi: 10.1002/pro.3218. Epub 2017 Jul 26. Protein Sci. 2017. PMID: 28681555 Free PMC article.
Plasmodium falciparum, the causative agent of malaria, employs a diverse array of surface displayed proteins to promote dissemination and establish infection in the human host. Of these, Pf3D7_0606800 is highly immunogenic and has been designated a potential …
Plasmodium falciparum, the causative agent of malaria, employs a diverse array of surface displayed proteins to promote dissem …
Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1'-region optimisation.
Calic PPS, Vinh NB, Webb CT, Malcolm TR, Ngo A, Lowes K, Drinkwater N, McGowan S, Scammells PJ. Calic PPS, et al. Eur J Med Chem. 2023 Feb 15;248:115051. doi: 10.1016/j.ejmech.2022.115051. Epub 2022 Dec 29. Eur J Med Chem. 2023. PMID: 36634455
Malaria remains a global health threat and growing resistance to artemisinin-based therapies calls for therapeutic agents with novel mechanisms of action. The Plasmodium spp M1 and M17 metalloaminopeptidases have been identified as attractive new antimalarial drug targets …
Malaria remains a global health threat and growing resistance to artemisinin-based therapies calls for therapeutic agents with novel mechani …
72 results