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The following term was not found in PubMed: 1018300
Page 1
Identification and characterization of DNA endonucleases in Plasmodium falciparum 3D7 clone.
Jiang N, Tu Z, Zhang Y, Li J, Feng Y, Yang N, Sang X, Chen Q. Jiang N, et al. Malar J. 2018 Jun 18;17(1):232. doi: 10.1186/s12936-018-2388-0. Malar J. 2018. PMID: 29914511 Free PMC article.
BACKGROUND: Plasmodium falciparum is the most virulent parasite of the five Plasmodium species that cause human malaria, and biological analysis of the parasite is critical for the development of novel strategies for disease control. ...The seven DNA endonucl …
BACKGROUND: Plasmodium falciparum is the most virulent parasite of the five Plasmodium species that cause human malaria …
Identifying Fast and Slow-Acting Antimalarial Compounds of Pandemic Response Box Against Blood-Stage Culture of Plasmodium falciparum 3D7.
Rajendran V, Naveen NC. Rajendran V, et al. Curr Microbiol. 2024 Jan 30;81(3):81. doi: 10.1007/s00284-023-03601-9. Curr Microbiol. 2024. PMID: 38289473
The evolving clinical resistance in Plasmodium falciparum and the spike in malarial cases after the COVID-19 outbreak has triggered a search for new antimalarials effective against multi-drug-resistant P. falciparum strains. In this study, we assessed the tim …
The evolving clinical resistance in Plasmodium falciparum and the spike in malarial cases after the COVID-19 outbreak has trig …
Fungal-derived methyldeoxaphomins target Plasmodium falciparum segregation through the inhibition of PfActin1.
Jiang T, Lee JW, Collins JE, Schaefer S, Chen D, Nardella F, Wendt K, Peramuna TG, Paes R, McLellan JL, Bhasin J, Durst GL, Hanson KK, Chakrabarti D, Cichewicz RH, Winzeler EA. Jiang T, et al. Proc Natl Acad Sci U S A. 2025 Feb 25;122(8):e2418871122. doi: 10.1073/pnas.2418871122. Epub 2025 Feb 18. Proc Natl Acad Sci U S A. 2025. PMID: 40138707 Free PMC article.
In vitro evolution and whole genome analysis in Plasmodium falciparum with the most potent member, NPDG-F (EC(50) of 550 nM in Dd2; 290 nM in 3D7), shows that parasite resistance to methyldeoxaphomins is strongly associated with mutations in PfActin1 (PF3D …
In vitro evolution and whole genome analysis in Plasmodium falciparum with the most potent member, NPDG-F (EC(50) of 550 nM in …
Detection of Developmental Asexual Stage-Specific RNA Editing Events in Plasmodium falciparum 3D7 Malaria Parasite.
Azad MTA, Sugi T, Qulsum U, Kato K. Azad MTA, et al. Microorganisms. 2024 Jan 10;12(1):137. doi: 10.3390/microorganisms12010137. Microorganisms. 2024. PMID: 38257964 Free PMC article.
Transcriptional variation has been studied but post-transcriptional modification due to RNA editing has not been investigated in Plasmodium. We investigated developmental stage-specific RNA editing in selected genes in Plasmodium falciparum 3D7. ...In …
Transcriptional variation has been studied but post-transcriptional modification due to RNA editing has not been investigated in Plasmodi …
Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria.
Woolley SD, Marquart L, Woodford J, Chalon S, Moehrle JJ, McCarthy JS, Barber BE. Woolley SD, et al. Malar J. 2021 Dec 20;20(1):470. doi: 10.1186/s12936-021-04003-7. Malar J. 2021. PMID: 34930260 Free PMC article.
Induced blood stage malaria volunteer infection studies (IBSM-VIS) provide a unique opportunity to evaluate the haematological response to early Plasmodium falciparum and Plasmodium vivax infection. METHODS: This study was an analysis of the haemoglobin, red …
Induced blood stage malaria volunteer infection studies (IBSM-VIS) provide a unique opportunity to evaluate the haematological response to e …
Dinuclear and mononuclear metal(II) polypyridyl complexes against drug-sensitive and drug-resistant Plasmodium falciparum and their mode of action.
Lai JW, Maah MJ, Tan KW, Sarip R, Lim YAL, Ganguly R, Khaw LT, Ng CH. Lai JW, et al. Malar J. 2022 Dec 17;21(1):386. doi: 10.1186/s12936-022-04406-0. Malar J. 2022. PMID: 36528584 Free PMC article.
Widespread occurrence of artemisinin-resistant Plasmodium falciparum strains from the Greater Mekong Subregion is alarming. This hinders the national economies, as well as being a major drawback in the effective control and elimination of malaria worldwide. ...The i …
Widespread occurrence of artemisinin-resistant Plasmodium falciparum strains from the Greater Mekong Subregion is alarming. Th …
Plasmodium falciparum DDX55 is a nucleocytoplasmic protein and a 3'-5' direction-specific DNA helicase.
Yasmin R, Kaur I, Tuteja R. Yasmin R, et al. Protoplasma. 2020 Jul;257(4):1049-1067. doi: 10.1007/s00709-020-01495-z. Epub 2020 Mar 3. Protoplasma. 2020. PMID: 32125511
Although artemisinin combination therapies (ACTs) are contributing to substantial decline in the worldwide malaria burden, it is becoming vulnerable by the emergence of artemisinin resistance in Plasmodium falciparum leading to clinical failure of ACTs in Southeast …
Although artemisinin combination therapies (ACTs) are contributing to substantial decline in the worldwide malaria burden, it is becoming vu …
Extracellular Proteomic Profiling from the Erythrocytes Infected with Plasmodium Falciparum 3D7 Holds Promise for the Detection of Biomarkers.
Joshi U, Pandya M, Gupta S, George LB, Highland H. Joshi U, et al. Protein J. 2024 Aug;43(4):819-833. doi: 10.1007/s10930-024-10212-1. Epub 2024 Jul 15. Protein J. 2024. PMID: 39009910
Plasmodium falciparum (P. falciparum), which causes the most severe form of malaria, if left untreated, has 24 h window in which it can cause severe illness and even death. The aim of this study was to create the most comprehensive and informative secretory-p …
Plasmodium falciparum (P. falciparum), which causes the most severe form of malaria, if left untreated, has 24 h window …
Characterization of Plasmodium falciparum prohibitins as novel targets to block infection in humans by impairing the growth and transmission of the parasite.
Saini M, Ngwa CJ, Marothia M, Verma P, Ahmad S, Kumari J, Anand S, Vandana V, Goyal B, Chakraborti S, Pandey KC, Garg S, Pati S, Ranganathan A, Pradel G, Singh S. Saini M, et al. Biochem Pharmacol. 2023 Jun;212:115567. doi: 10.1016/j.bcp.2023.115567. Epub 2023 Apr 22. Biochem Pharmacol. 2023. PMID: 37088154
Prohibitins (PHBs) are highly conserved pleiotropic proteins as they have been shown to mediate key cellular functions. Here, we characterize PHBs encoding putative genes ofPlasmodium falciparum by exploiting different orthologous models. We demonstrated that PfPHB1 …
Prohibitins (PHBs) are highly conserved pleiotropic proteins as they have been shown to mediate key cellular functions. Here, we characteriz …
Identification of a conserved var gene in different Plasmodium falciparum strains.
Dimonte S, Bruske EI, Enderes C, Otto TD, Turner L, Kremsner P, Frank M. Dimonte S, et al. Malar J. 2020 May 29;19(1):194. doi: 10.1186/s12936-020-03257-x. Malar J. 2020. PMID: 32471507 Free PMC article.
BACKGROUND: The multicopy var gene family of Plasmodium falciparum is of crucial importance for pathogenesis and antigenic variation. So far only var2csa, the var gene responsible for placental malaria, was found to be highly conserved among all P. falciparum …
BACKGROUND: The multicopy var gene family of Plasmodium falciparum is of crucial importance for pathogenesis and antigenic var …
79 results