Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 2
2005 1
2006 1
2008 1
2011 1
2013 4
2014 3
2015 3
2016 2
2018 2
2020 3
2021 1
2022 2
2023 6
2024 2
2025 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

34 results

Results by year

Filters applied: . Clear all
Page 1
PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel LM, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. Appel LM, et al. Nat Commun. 2021 Oct 19;12(1):6078. doi: 10.1038/s41467-021-26360-2. Nat Commun. 2021. PMID: 34667177 Free PMC article.
Key neuronal genes are aberrantly expressed in Phf3 knock-out mouse embryonic stem cells, resulting in impaired neuronal differentiation. Our data suggest that PHF3 acts as a prominent effector of neuronal gene regulation by bridging transcription with mRNA decay... …
Key neuronal genes are aberrantly expressed in Phf3 knock-out mouse embryonic stem cells, resulting in impaired neuronal differentiat …
The SPOC proteins DIDO3 and PHF3 co-regulate gene expression and neuronal differentiation.
Benedum J, Franke V, Appel LM, Walch L, Bruno M, Schneeweiss R, Gruber J, Oberndorfer H, Frank E, Strobl X, Polyansky A, Zagrovic B, Akalin A, Slade D. Benedum J, et al. Nat Commun. 2023 Nov 30;14(1):7912. doi: 10.1038/s41467-023-43724-y. Nat Commun. 2023. PMID: 38036524 Free PMC article.
In the absence of PHF3, DIDO3 is upregulated as a compensatory mechanism. In addition to shared gene targets, DIDO specifically regulates genes required for lipid metabolism. Collectively, our work reveals multiple layers of gene expression regulation by the DIDO3 and P …
In the absence of PHF3, DIDO3 is upregulated as a compensatory mechanism. In addition to shared gene targets, DIDO specifically regul …
Lnc-PHF3-3 aggravates the chemoresistance of osteosarcoma cells to doxorubicin via the miR-142-3p/HMGB1 axis.
Zhou J, Yang M, Zhao W, Zhang H, Cao L, Li Q, Wang G. Zhou J, et al. Transl Oncol. 2025 Mar;53:102328. doi: 10.1016/j.tranon.2025.102328. Epub 2025 Feb 18. Transl Oncol. 2025. PMID: 39970626 Free PMC article.
Gain-of-function and loss-of-function assays were performed to examine the effect of lncRNA Lnc-PHF3-3 and miR-142-3p on chemoresistance of OS cells. Using fluorescence reporter and western blot assays, we also explored the possible mechanisms of Lnc-PHF3-3 in OS ce …
Gain-of-function and loss-of-function assays were performed to examine the effect of lncRNA Lnc-PHF3-3 and miR-142-3p on chemoresista …
PhCHS5 and PhF3'5'H Genes Over-Expression in Petunia (Petunia hybrida) and Phalaenopsis (Phalaenopsis aphrodite) Regulate Flower Color and Branch Number.
Lou Y, Zhang Q, Xu Q, Yu X, Wang W, Gai R, Ming F. Lou Y, et al. Plants (Basel). 2023 Jun 2;12(11):2204. doi: 10.3390/plants12112204. Plants (Basel). 2023. PMID: 37299183 Free PMC article.
Compared with WT, 35S::PhCHS5 and 35S::PhF3'5'H both had deeper color and higher anthocyanin content in Petunia plants. Additionally, a phenotypic comparison with wild-type controls indicated the PhCHS5 or PhF3'5'H-transgenic Phalaenopsis produced more branches, pet …
Compared with WT, 35S::PhCHS5 and 35S::PhF3'5'H both had deeper color and higher anthocyanin content in Petunia plants. Additionally, …
PHF3-specific antibody responses in over 60% of patients with glioblastoma multiforme.
Struss AK, Romeike BF, Munnia A, Nastainczyk W, Steudel WI, König J, Ohgaki H, Feiden W, Fischer U, Meese E. Struss AK, et al. Oncogene. 2001 Jul 12;20(31):4107-14. doi: 10.1038/sj.onc.1204552. Oncogene. 2001. PMID: 11464277
While previous SEREX studies revealed allogenic antibody responses up to 40%, our results for PHF3 represent the highest reported rate for a specific antibody response. We show that GBM patients with an antibody response against PHF3 show significant better survival …
While previous SEREX studies revealed allogenic antibody responses up to 40%, our results for PHF3 represent the highest reported rat …
PHF3 expression is frequently reduced in glioma.
Fischer U, Struss AK, Hemmer D, Michel A, Henn W, Steudel WI, Meese E. Fischer U, et al. Cytogenet Cell Genet. 2001;94(3-4):131-6. doi: 10.1159/000048804. Cytogenet Cell Genet. 2001. PMID: 11856869
Here we report the identification and expression analysis of a novel gene from human chromosome 6q12 that is considered to be the third member of a family of PHD finger containing genes and is termed PHF3. PHF3 is ubiquitously expressed in normal tissues including b …
Here we report the identification and expression analysis of a novel gene from human chromosome 6q12 that is considered to be the third memb …
Common PTP4A1-PHF3-EYS variants are specific for alcohol dependence.
Zuo L, Wang K, Wang G, Pan X, Zhang X, Zhang H, Luo X. Zuo L, et al. Am J Addict. 2014 Jul-Aug;23(4):411-4. doi: 10.1111/j.1521-0391.2013.12115.x. Epub 2013 Sep 13. Am J Addict. 2014. PMID: 24961364 Free PMC article.
BACKGROUND AND OBJECTIVES: We previously reported a risk genomic region (ie, PTP4A1-PHF3-EYS) for alcohol dependence in a genome-wide association study (GWAS). We also reported a rare variant constellation across this region that was significantly associated with alcohol d …
BACKGROUND AND OBJECTIVES: We previously reported a risk genomic region (ie, PTP4A1-PHF3-EYS) for alcohol dependence in a genome-wide …
Immunotherapies targeting neoantigens are effective in PD-1 blockade-resistant tumors.
Sun C, Nagaoka K, Kobayashi Y, Maejima K, Nakagawa H, Nakajima J, Kakimi K. Sun C, et al. Int J Cancer. 2023 Apr 1;152(7):1463-1475. doi: 10.1002/ijc.34382. Epub 2022 Dec 13. Int J Cancer. 2023. PMID: 36451303
Using ASB-XIV-specific CD8(+) T cells, we screened a panel of 257 neoepitope peptides derived from ASB-XIV missense and indel mutations. Mutated Phf3 peptide (mPhf3) was successfully identified as an immunogenic neoepitope. Prophylactic mPhf3-DC vaccination inhibited ASB-X …
Using ASB-XIV-specific CD8(+) T cells, we screened a panel of 257 neoepitope peptides derived from ASB-XIV missense and indel mutations. Mut …
Autoantibodies against GLEA2 and PHF3 in glioblastoma: tumor-associated autoantibodies correlated with prolonged survival.
Pallasch CP, Struss AK, Munnia A, König J, Steudel WI, Fischer U, Meese E. Pallasch CP, et al. Int J Cancer. 2005 Nov 10;117(3):456-9. doi: 10.1002/ijc.20929. Int J Cancer. 2005. PMID: 15906353
Relating patient survival to the occurrence of autoantibodies against either GLEA1, GLEA2 or PHF3, we found a significant prolonged survival for glioblastoma patients positive for autoantibodies against GLEA2 (p = 0.0115) and PHF3 (p = 0.0031), respectively. The med …
Relating patient survival to the occurrence of autoantibodies against either GLEA1, GLEA2 or PHF3, we found a significant prolonged s …
Genomic analysis of 116 autism families strengthens known risk genes and highlights promising candidates.
Viggiano M, Ceroni F, Visconti P, Posar A, Scaduto MC, Sandoni L, Baravelli I, Cameli C, Rochat MJ, Maresca A, Vaisfeld A, Gentilini D, Calzari L, Carelli V, Zody MC, Maestrini E, Bacchelli E. Viggiano M, et al. NPJ Genom Med. 2024 Mar 22;9(1):21. doi: 10.1038/s41525-024-00411-1. NPJ Genom Med. 2024. PMID: 38519481 Free PMC article.
Potentially damaging CNVs (pdCNVs) provided support to the involvement of inherited variants in PHF3, NEGR1, TIAM1 and HOMER1 in neurodevelopmental disorders (NDD), although mostly acting as susceptibility factors with incomplete penetrance. ...
Potentially damaging CNVs (pdCNVs) provided support to the involvement of inherited variants in PHF3, NEGR1, TIAM1 and HOMER1 in neur …
34 results