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Page 1
Noninvasive Vagus Nerve Stimulation in Postural Tachycardia Syndrome: A Randomized Clinical Trial.
Stavrakis S, Chakraborty P, Farhat K, Whyte S, Morris L, Abideen Asad ZU, Karfonta B, Anjum J, Matlock HG, Cai X, Yu X. Stavrakis S, et al. JACC Clin Electrophysiol. 2024 Feb;10(2):346-355. doi: 10.1016/j.jacep.2023.10.015. Epub 2023 Nov 22. JACC Clin Electrophysiol. 2024. PMID: 37999672 Free PMC article. Clinical Trial.
Preliminary studies show that transcutaneous vagus nerve stimulation (tVNS) is beneficial in animal models of postural tachycardia syndrome (POTS). OBJECTIVES: In this study the authors conducted a sham-controlled, double-blind, randomized clinical trial to examine the eff …
Preliminary studies show that transcutaneous vagus nerve stimulation (tVNS) is beneficial in animal models of postural tachycardia syndrome …
Postural tachycardia syndrome - Diagnosis, physiology, and prognosis.
Arnold AC, Ng J, Raj SR. Arnold AC, et al. Auton Neurosci. 2018 Dec;215:3-11. doi: 10.1016/j.autneu.2018.02.005. Epub 2018 Feb 28. Auton Neurosci. 2018. PMID: 29523389 Free PMC article. Review.
The most sensitive method to detect POTS is a detailed medical history, physical examination with orthostatic vital signs or brief tilt table test, and a resting 12-lead electrocardiogram. ...This review will outline the current understanding of diagnosis, pathophys …
The most sensitive method to detect POTS is a detailed medical history, physical examination with orthostatic vital signs or brief ti …
Deciphering the sinus tachycardias.
Yusuf S, Camm AJ. Yusuf S, et al. Clin Cardiol. 2005 Jun;28(6):267-76. doi: 10.1002/clc.4960280603. Clin Cardiol. 2005. PMID: 16028460 Free PMC article. Review.
Normal sinus tachycardia (i.e., secondary), inappropriate sinus tachycardia, postural orthostatic tachycardia syndrome (POTS) and sinus node reentry tachycardia make up this group of arrhythmias. Their definitions, clinical features, diagnostic criteria, pathophysiologic m …
Normal sinus tachycardia (i.e., secondary), inappropriate sinus tachycardia, postural orthostatic tachycardia syndrome (POTS) and sin …
Screening for postural orthostatic tachycardia syndrome using 24-hour electrocardiogram recording in patients with long coronavirus disease.
Hupin D, Pichot V, Bäck M, Nygren-Bonnier M, Reistam U, Runold M, Bruchfeld J, Dupré C, Da Costa A, Romeyer C, Roche F, Ståhlberg M, Fedorowski A, Nickander J. Hupin D, et al. Heart Rhythm O2. 2025 May 8;6(7):949-955. doi: 10.1016/j.hroo.2025.04.011. eCollection 2025 Jul. Heart Rhythm O2. 2025. PMID: 40734755 Free PMC article.
As one of the most typical phenotypes of cardiovascular autonomic dysfunction, postural orthostatic tachycardia syndrome (POTS) is commonly observed as a sequelae of coronavirus disease infection. OBJECTIVE: This study aimed to develop and test a 24-hour electrocardiogr …
As one of the most typical phenotypes of cardiovascular autonomic dysfunction, postural orthostatic tachycardia syndrome (POTS) is co …
Comparative cohort study of post-acute COVID-19 infection with a nested, randomized controlled trial of ivabradine for those with postural orthostatic tachycardia syndrome (the COVIVA study).
Saunders D, Arnold TB, Lavender JM, Bi D, Alcover K, Hellwig LD, Leazer ST, Mohammed R, Markos B, Perera K, Shaw D, Kobi P, Evans M, Mains A, Tanofsky-Kraff M, Goguet E, Mitre E, Pratt KP, Dalgard CL, Haigney MC. Saunders D, et al. Front Neurol. 2025 Jul 7;16:1550636. doi: 10.3389/fneur.2025.1550636. eCollection 2025. Front Neurol. 2025. PMID: 40692561 Free PMC article.
Those in the cohort who meet diagnostic criteria for POTS or IST will be included in a nested prospective, randomized, placebo-controlled trial to assess the impact of ivabradine on symptoms and heart rate, assessed non-invasively based on physiologic response and ambulato …
Those in the cohort who meet diagnostic criteria for POTS or IST will be included in a nested prospective, randomized, placebo-contro …
The preponderance of initial orthostatic hypotension in postural tachycardia syndrome.
Stewart JM, Kota A, O'Donnell-Smith MB, Visintainer P, Terilli C, Medow MS. Stewart JM, et al. J Appl Physiol (1985). 2020 Sep 1;129(3):459-466. doi: 10.1152/japplphysiol.00540.2020. Epub 2020 Jul 23. J Appl Physiol (1985). 2020. PMID: 32702262 Free PMC article.
Subjects were instrumented for electrocardiography and beat-to-beat BP. After 10 min supine, subjects stood for 5 min. Following supine recovery, subjects underwent 70 head-up tilt for 10 min to test for POTS. ...POTS-IOH and control-IOH subjects had similar …
Subjects were instrumented for electrocardiography and beat-to-beat BP. After 10 min supine, subjects stood for 5 min. Following supi …
Short and long term effects of a two-week transcutaneous vagus nerve stimulation in hyperadrenergic postural orthostatic tachycardia syndrome: a proof-of-concept trial.
Shiffer D, Rigo S, Minonzio M, Yarsuvat DT, Tobaldini E, Furlan L, Montano N, Cairo B, Porta A, Zamunér AR, Bonovas S, Urechie V, Biaggioni I, Diedrich A, Furlan R. Shiffer D, et al. Eur J Intern Med. 2026 Jan;143:106529. doi: 10.1016/j.ejim.2025.106529. Epub 2025 Sep 27. Eur J Intern Med. 2026. PMID: 41016890
BACKGROUND AND AIMS: Hyperadrenergic POTS (Hyper-POTS) is characterized by excessive central sympathetic activity and impaired cardiovagal modulation. ...Repetitive tVNS may similarly restore autonomic balance and improve symptoms in Hyper-POTS. METHODS: Twen …
BACKGROUND AND AIMS: Hyperadrenergic POTS (Hyper-POTS) is characterized by excessive central sympathetic activity and impaired …
Diagnostic Value of Synchronous Heart Sound Electrocardiogram in Children with Postural Tachycardia Syndrome.
Zhang F, Chen Y, Zhang L, Hu B, Lin Z, Niu M, Ding S, Jiang F, Pan J. Zhang F, et al. Pediatric Health Med Ther. 2025 Sep 5;16:237-247. doi: 10.2147/PHMT.S527129. eCollection 2025. Pediatric Health Med Ther. 2025. PMID: 40959677 Free PMC article.
BACKGROUND: Postural tachycardia syndrome (POTS) is a common autonomic dysfunction in children. The head-up test (HUT) or head-up tilt test (HUTT) is typically required to confirm the diagnosis of POTS. This study describes a novel approach to diagnosing POTS …
BACKGROUND: Postural tachycardia syndrome (POTS) is a common autonomic dysfunction in children. The head-up test (HUT) or head-up til …
Monitoring of cardiorespiratory vagal desynchrony using novel biomarkers derived from smartwatch electrocardiograms in a patient recovering from long COVID: case report.
Kranck G, Ståhlberg M, Andersson U, Lundin J, Fedorowski A. Kranck G, et al. Eur Heart J Case Rep. 2025 Aug 29;9(10):ytaf425. doi: 10.1093/ehjcr/ytaf425. eCollection 2025 Oct. Eur Heart J Case Rep. 2025. PMID: 41050528 Free PMC article.
With over 200 million electrocardiogram (ECG)-enabled smartwatches sold worldwide, these devices offer a promising solution for at-home diagnostics and disease tracking. ...Initially, the patient experienced severe fatigue and heart rhythm changes consistent with POTS …
With over 200 million electrocardiogram (ECG)-enabled smartwatches sold worldwide, these devices offer a promising solution for at-ho …
78 results