Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2020 1
2021 1
2023 2
2024 3
2025 6
2026 4

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

16 results

Results by year

Filters applied: . Clear all
Page 1
The Relationship Between Hypermobile Ehlers-Danlos Syndrome (hEDS), Postural Orthostatic Tachycardia Syndrome (POTS), and Mast Cell Activation Syndrome (MCAS).
Kucharik AH, Chang C. Kucharik AH, et al. Clin Rev Allergy Immunol. 2020 Jun;58(3):273-297. doi: 10.1007/s12016-019-08755-8. Clin Rev Allergy Immunol. 2020. PMID: 31267471 Review.
In recent years, an association between hypermobile Ehlers-Danlos syndrome (hEDS), mast cell activation syndrome (MCAS), and postural orthostatic tachycardia syndrome (POTS) has garnered attention and patients are increasingly presenting with this tria …
In recent years, an association between hypermobile Ehlers-Danlos syndrome (hEDS), mast cell activation syndrome (MCAS) …
AGA Clinical Practice Update on GI Manifestations and Autonomic or Immune Dysfunction in Hypermobile Ehlers-Danlos Syndrome: Expert Review.
Aziz Q, Harris LA, Goodman BP, Simrén M, Shin A. Aziz Q, et al. Clin Gastroenterol Hepatol. 2025 Jul;23(8):1291-1302. doi: 10.1016/j.cgh.2025.02.015. Epub 2025 May 19. Clin Gastroenterol Hepatol. 2025. PMID: 40387691 Review.
DESCRIPTION: The purpose of this Clinical Practice Update Expert Review is to describe key principles in the evaluation and management of patients with disorders of gut-brain interaction (DGBI) and hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobility spectrum …
DESCRIPTION: The purpose of this Clinical Practice Update Expert Review is to describe key principles in the evaluation and management of pa …
The relationship between mast cell activation syndrome, postural tachycardia syndrome, and Ehlers-Danlos syndrome.
Wang E, Ganti T, Vaou E, Hohler A. Wang E, et al. Allergy Asthma Proc. 2021 May 1;42(3):243-246. doi: 10.2500/aap.2021.42.210022. Allergy Asthma Proc. 2021. PMID: 33980338
Background: Postural tachycardia syndrome (POTS), hypermobile Ehlers-Danlos syndrome (EDS), and mast cell activation syndrome (MCAS) can occur in the same patient. ...The demographics of the patients and diagnoses of POTS, EDS, or MCAS we …
Background: Postural tachycardia syndrome (POTS), hypermobile Ehlers-Danlos syndrome (EDS), and mast cell activation sy …
The Suggested Relationships Between Common GI Symptoms and Joint Hypermobility, POTS, and MCAS.
Quigley EMM, Noble O, Ansari U. Quigley EMM, et al. Gastroenterol Hepatol (N Y). 2024 Aug;20(8):479-489. Gastroenterol Hepatol (N Y). 2024. PMID: 39205953 Free PMC article.
This cluster is composed of diagnoses of hypermobility spectrum disorders (HSDs) such as joint hypermobility and hypermobile variant Ehlers-Danlos syndrome (hEDS), postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS …
This cluster is composed of diagnoses of hypermobility spectrum disorders (HSDs) such as joint hypermobility and hypermobile variant Ehle …
Dysautonomia, Hypermobility Spectrum Disorders and Mast Cell Activation Syndrome as Migraine Comorbidities.
Blitshteyn S. Blitshteyn S. Curr Neurol Neurosci Rep. 2023 Nov;23(11):769-776. doi: 10.1007/s11910-023-01307-w. Epub 2023 Oct 17. Curr Neurol Neurosci Rep. 2023. PMID: 37847487 Review.
The most common autonomic disorders are postural orthostatic tachycardia syndrome (POTS), neurocardiogenic syncope (NCS), and orthostatic hypotension (OH), which may be encountered in clinical practice as part of a triad of dysautonomia, hypermobility spectrum disorders (H …
The most common autonomic disorders are postural orthostatic tachycardia syndrome (POTS), neurocardiogenic syncope (NCS), and orthost …
Neuropsychiatric Manifestations of Mast Cell Activation Syndrome and Response to Mast-Cell-Directed Treatment: A Case Series.
Weinstock LB, Nelson RM, Blitshteyn S. Weinstock LB, et al. J Pers Med. 2023 Oct 31;13(11):1562. doi: 10.3390/jpm13111562. J Pers Med. 2023. PMID: 38003876 Free PMC article.
All eight patients were subsequently diagnosed with mast cell activation syndrome; six had comorbid autonomic disorders, the most common being postural orthostatic tachycardia syndrome; and four had hypermobile Ehlers-Danlos syndrome. All patients experienced signif …
All eight patients were subsequently diagnosed with mast cell activation syndrome; six had comorbid autonomic disorders, the most common bei …
Autonomic symptom burden, comorbidities and quality of life in women with Hypermobility Spectrum Disorders and hypermobile Ehlers-Danlos syndrome.
Collins Hutchinson ML, Liang E, Fuster E, Blitshteyn S. Collins Hutchinson ML, et al. Auton Neurosci. 2025 Dec;262:103356. doi: 10.1016/j.autneu.2025.103356. Epub 2025 Oct 14. Auton Neurosci. 2025. PMID: 41118678
BACKGROUND: Hypermobility Spectrum Disorders (HSD) and hypermobile Ehlers-Danlos syndrome (h-EDS) are multisystemic connective tissue disorders involving joint hypermobility and numerous other manifestations. ...More than half of participants in this cohort had P …
BACKGROUND: Hypermobility Spectrum Disorders (HSD) and hypermobile Ehlers-Danlos syndrome (h-EDS) are multisystemic connective …
Association of postural orthostatic tachycardia syndrome, hypermobility spectrum disorders, and mast cell activation syndrome in young patients; prevalence, overlap and response to therapy depends on the definition.
Yao L, Subramaniam K, Raja KM, Arunachalam A, Tran A, Pandey T, Ravishankar S, Suggala S, Hendrickson C, Maxwell AJ. Yao L, et al. Front Neurol. 2025 Apr 25;16:1513199. doi: 10.3389/fneur.2025.1513199. eCollection 2025. Front Neurol. 2025. PMID: 40352770 Free PMC article.
BACKGROUND: The close association of syndromes of orthostatic intolerance with and without postural orthostatic tachycardia syndrome (POTS) with Joint Hypermobility Disorders (JHD) including Hypermobility Spectrum Disorder (HSD) and hypermobile Ehlers Danlos …
BACKGROUND: The close association of syndromes of orthostatic intolerance with and without postural orthostatic tachycardia syndrome (POT …
Hyperventilation during rest and exercise in orthostatic intolerance and Spiky-Leaky Syndrome.
Hashemizad A, Dela Cruz J, Narayan A, Maxwell AJ. Hashemizad A, et al. Front Neurol. 2025 Apr 17;16:1512671. doi: 10.3389/fneur.2025.1512671. eCollection 2025. Front Neurol. 2025. PMID: 40313612 Free PMC article.
BACKGROUND: Orthostatic intolerance, with or without postural orthostatic tachycardia syndrome (POTS), is collectively referred to as orthostatic intolerance dysautonomia syndromes (OIDS). ...These exercise parameters may serve as markers for POTS physiology and sym …
BACKGROUND: Orthostatic intolerance, with or without postural orthostatic tachycardia syndrome (POTS), is collectively referred to as …
Gastrointestinal Manifestations of Hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders: A Mentored Review.
Ahmed A, Paudel B, Sharma A. Ahmed A, et al. Dig Dis Sci. 2026 May 7. doi: 10.1007/s10620-026-09958-8. Online ahead of print. Dig Dis Sci. 2026. PMID: 42098539 Review.
BACKGROUND: Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder that is often diagnosed after diagnostic delays due to reliance on heightened clinical suspicion. ...In addition, hEDS/HSD is closely linked with POTS and MCAS, which …
BACKGROUND: Hypermobile Ehlers-Danlos Syndrome (hEDS) is a connective tissue disorder that is often diagnosed after diagnostic …
16 results