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Page 1
AGA Clinical Practice Update on GI Manifestations and Autonomic or Immune Dysfunction in Hypermobile Ehlers-Danlos Syndrome: Expert Review.
Aziz Q, Harris LA, Goodman BP, Simrén M, Shin A. Aziz Q, et al. Clin Gastroenterol Hepatol. 2025 Jul;23(8):1291-1302. doi: 10.1016/j.cgh.2025.02.015. Epub 2025 May 19. Clin Gastroenterol Hepatol. 2025. PMID: 40387691 Review.
BEST PRACTICE ADVICE 2: Testing for POTS/MCAS should be targeted to patients presenting with clinical manifestations of POTS/MCAS, but universal testing for POTS/MCAS in all patients with hEDS/HSDs is not supported by the current evidence. ...In addition to g …
BEST PRACTICE ADVICE 2: Testing for POTS/MCAS should be targeted to patients presenting with clinical manifestations of POTS/M …
Gastrointestinal motility evaluation in children with orthostatic intolerance: Mayo Clinic experience.
Manini ML, Barazi A, Khemani D, Abd-Rabu R, Absah I, Fischer PR, Mara K, Stephens M, Camilleri M. Manini ML, et al. Neurogastroenterol Motil. 2020 Aug;32(8):e13863. doi: 10.1111/nmo.13863. Epub 2020 Jun 1. Neurogastroenterol Motil. 2020. PMID: 32483845
We hypothesize that patients with POTS, OH, and SOI show differences in GI symptoms and motility test and that heart rate (HR) changes on HUT predict severity of GI dysmotility. ...Among 100 POTS, 34 OH, and 95 SOI patients, no significant differences in GI s …
We hypothesize that patients with POTS, OH, and SOI show differences in GI symptoms and motility test and that heart rate (HR) …
Gastrointestinal Symptoms and Systemic Comorbidities in Patients With POTS: A Systematic Review and Meta-Analysis.
Kulin D, Shah A, Fairlie T, Staller K, Nurko S, Keefer L, Aziz Q, Drossman DA, Jones MP, Holtmann G. Kulin D, et al. Neurogastroenterol Motil. 2026 Apr;38(4):e70305. doi: 10.1111/nmo.70305. Neurogastroenterol Motil. 2026. PMID: 41952073 Free PMC article. Review.
We conducted a systematic review and meta-analysis to assess the prevalence of gastrointestinal symptoms and comorbid conditions in POTS patients. METHODS: Electronic databases were searched from inception until May 2025 for studies reporting gastrointestinal …
We conducted a systematic review and meta-analysis to assess the prevalence of gastrointestinal symptoms and comorbid conditions in …
Regional Gastrointestinal Transit and Contractility Patterns Vary in Postural Orthostatic Tachycardia Syndrome (POTS).
Zhou W, Zikos TA, Clarke JO, Nguyen LA, Triadafilopoulos G, Neshatian L. Zhou W, et al. Dig Dis Sci. 2021 Dec;66(12):4406-4413. doi: 10.1007/s10620-020-06808-z. Epub 2021 Jan 11. Dig Dis Sci. 2021. PMID: 33428036
These patients often have multiple GI complaints with a severe impact on their quality of life. GI dysmotility patterns in POTS remains poorly understood and difficult to manage. AIMS: The aim of this study was to investigate the diagnostic yield of wireless motility …
These patients often have multiple GI complaints with a severe impact on their quality of life. GI dysmotility patterns in POTS remai …
Gastrointestinal symptoms in postural tachycardia syndrome: a systematic review.
Mehr SE, Barbul A, Shibao CA. Mehr SE, et al. Clin Auton Res. 2018 Aug;28(4):411-421. doi: 10.1007/s10286-018-0519-x. Epub 2018 Mar 16. Clin Auton Res. 2018. PMID: 29549458 Free PMC article.
In patients with POTS and Ehlers-Danlos syndromes, structural and functional abnormalities in the gastrointestinal connective tissue may play a significant role, whereas in neuropathic POTS, the gastrointestinal tract motility and gut hormonal s …
In patients with POTS and Ehlers-Danlos syndromes, structural and functional abnormalities in the gastrointestinal connective …
Evaluation of postural tachycardia syndrome (POTS).
Goodman BP. Goodman BP. Auton Neurosci. 2018 Dec;215:12-19. doi: 10.1016/j.autneu.2018.04.004. Epub 2018 Apr 22. Auton Neurosci. 2018. PMID: 29705015 Review.
The purpose of autonomic testing is to confirm a POTS diagnosis, exclude other causes of orthostatic intolerance, and may provide for characterization of POTS into neuropathic and hyperadrenergic subtypes. Other diagnostic studies, such as epidermal skin punch biops …
The purpose of autonomic testing is to confirm a POTS diagnosis, exclude other causes of orthostatic intolerance, and may provide for …
Mechanisms and management of gastrointestinal symptoms in postural orthostatic tachycardia syndrome.
Tu Y, Abell TL, Raj SR, Mar PL. Tu Y, et al. Neurogastroenterol Motil. 2020 Dec;32(12):e14031. doi: 10.1111/nmo.14031. Epub 2020 Nov 2. Neurogastroenterol Motil. 2020. PMID: 33140561 Review.
In the current issue of Neurogastroenterology and Motility, Tai et al. explored the relationship between functional GI disorders among hEDS patients with and without concomitant POTS and showed that the hEDS-POTS cohort was more likely to have more than one G …
In the current issue of Neurogastroenterology and Motility, Tai et al. explored the relationship between functional GI disorders amon …
Postural Tachycardia Syndrome (POTS) and the GI Tract: A Primer for the Gastroenterologist.
DiBaise JK, Harris LA, Goodman B. DiBaise JK, et al. Am J Gastroenterol. 2018 Oct;113(10):1458-1467. doi: 10.1038/s41395-018-0215-4. Epub 2018 Aug 3. Am J Gastroenterol. 2018. PMID: 30072778 Review.
Gastrointestinal (GI) symptoms are reported commonly in patients with POTS and pose a considerable management challenge, making it imperative that gastroenterologists be aware of this condition and its GI comorbidities. ...General measures to treat POTS may l …
Gastrointestinal (GI) symptoms are reported commonly in patients with POTS and pose a considerable management challenge, makin …
Orthostatic intolerance and gastrointestinal motility in adolescents with nausea and abdominal pain.
Antiel RM, Risma JM, Grothe RM, Brands CK, Fischer PR. Antiel RM, et al. J Pediatr Gastroenterol Nutr. 2008 Mar;46(3):285-8. doi: 10.1097/MPG.0b013e318145a70c. J Pediatr Gastroenterol Nutr. 2008. PMID: 18376245
Patients with a heart rate change of 30 or more beats per minute on the heads-up tilt table test were assigned to the postural orthostatic tachycardia syndrome (POTS) group (n = 21), and those with a heart rate change of fewer than 30 beats per minute on the heads-up tilt …
Patients with a heart rate change of 30 or more beats per minute on the heads-up tilt table test were assigned to the postural orthostatic t …
Postural tachycardia syndrome: a heterogeneous and multifactorial disorder.
Benarroch EE. Benarroch EE. Mayo Clin Proc. 2012 Dec;87(12):1214-25. doi: 10.1016/j.mayocp.2012.08.013. Epub 2012 Nov 1. Mayo Clin Proc. 2012. PMID: 23122672 Free PMC article. Review.
POTS manifests with symptoms of cerebral hypoperfusion and excessive sympathoexcitation. ...Many patients with POTS also report symptoms not attributable to orthostatic intolerance, including those of functional gastrointestinal or bladder disorders, chronic …
POTS manifests with symptoms of cerebral hypoperfusion and excessive sympathoexcitation. ...Many patients with POTS also repor …
24 results