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Small Fiber Neuropathy.
Saperstein DS. Saperstein DS. Neurol Clin. 2020 Aug;38(3):607-618. doi: 10.1016/j.ncl.2020.04.001. Neurol Clin. 2020. PMID: 32703472 Review.
Small fiber neuropathy has a broad array of presentations. Length-dependent symptoms and findings present little diagnostic difficulty, but non-length-dependent or multifocal symptoms can be challenging. ...Avoidance of IENFD testing in situations where diagn …
Small fiber neuropathy has a broad array of presentations. Length-dependent symptoms and findings present little diagno …
Small fiber neuropathy in children, adolescents, and young adults with chronic orthostatic intolerance and postural orthostatic tachycardia syndrome: A retrospective study.
Moak JP, Ramwell CB, Gordish-Dressman H, Sule SD, Bettini E. Moak JP, et al. Auton Neurosci. 2024 Jun;253:103163. doi: 10.1016/j.autneu.2024.103163. Epub 2024 Mar 8. Auton Neurosci. 2024. PMID: 38537312
Statistical analysis was performed using Wilcoxon rank sum tests. RESULTS: In CAYA patients with OI or POTS and neuropathic symptoms, skin biopsy for small fiber neuropathy was abnormal in 53 %. ...CONCLUSION: Our data suggest a link between OI and …
Statistical analysis was performed using Wilcoxon rank sum tests. RESULTS: In CAYA patients with OI or POTS and neuropathic symptoms, …
Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome.
Azcue N, Del Pino R, Acera M, Fernández-Valle T, Ayo-Mentxakatorre N, Pérez-Concha T, Murueta-Goyena A, Lafuente JV, Prada A, López de Munain A, Ruiz Irastorza G, Martín-Iglesias D, Ribacoba L, Gabilondo I, Gómez-Esteban JC, Tijero-Merino B. Azcue N, et al. J Transl Med. 2023 Nov 15;21(1):814. doi: 10.1186/s12967-023-04678-3. J Transl Med. 2023. PMID: 37968647 Free PMC article.
The hemodynamic autonomic function was evaluated using the deep breathing technique, Valsalva maneuver, and Tilt test. The presence of autonomic and sensory small fiber neuropathy (SFN) was assessed with the Sudoscan and with heat and cold evoked potentials, …
The hemodynamic autonomic function was evaluated using the deep breathing technique, Valsalva maneuver, and Tilt test. The presence of auton …
Hypermobile Ehlers-Danlos Syndrome: Cerebrovascular, Autonomic and Neuropathic Features.
Novak P, Systrom DM, Marciano SP, Witte A, Warren A, Felsenstein D, Giannetti MP, Hamilton MJ, Nicoloro-SantaBarbara J, Castells M, Farhad K, Pilgrim DM, Mullally WJ, Fishman MC, Milunsky JM, Milunsky A, Krier J. Novak P, et al. Am J Med Open. 2025 Jul 18;14:100111. doi: 10.1016/j.ajmo.2025.100111. eCollection 2025 Dec. Am J Med Open. 2025. PMID: 40843452 Free PMC article.
Widespread but mild autonomic failure was present in 90% of hEDS patients on autonomic testing. Small fiber neuropathy using structural criteria was detected in 64%, and using combined structural and functional criteria in 82%. CONCLUSIONS: This study provide …
Widespread but mild autonomic failure was present in 90% of hEDS patients on autonomic testing. Small fiber neuropathy …
Small-fiber neuropathy with cardiac denervation in postural tachycardia syndrome.
Haensch CA, Tosch M, Katona I, Weis J, Isenmann S. Haensch CA, et al. Muscle Nerve. 2014 Dec;50(6):956-61. doi: 10.1002/mus.24245. Epub 2014 Aug 29. Muscle Nerve. 2014. PMID: 24647968
Our objective in this study was to evaluate the correlation between C-fiber involvement as shown by skin biopsy and adrenergic cardiac metaiodobenzylguanadine (MIBG) uptake in POTS patients. ...Low IENF density correlated with reduced cardiac MIBG uptake (r = 0.39, …
Our objective in this study was to evaluate the correlation between C-fiber involvement as shown by skin biopsy and adrenergic cardia …
Post-COVID-19 Vaccination (or Long Vax) Syndrome: Putative Manifestation, Pathophysiology, and Therapeutic Options.
Yong SJ, Kenny TA, Halim A, Munipalli B, Alhashem YN, AlSaihati H, Al-Subaie MF, Al Kaabi NA, Al Fares MA, Garout M, Sabour AA, Alshiekheid MA, Almansour ZH, Alotaibi J, Alrasheed HA, Alamri AA, Albayat H, Alamodi AS, Tombuloglu H, Mohapatra RK, Hazazi A, Rabaan AA. Yong SJ, et al. Rev Med Virol. 2025 Sep;35(5):e70070. doi: 10.1002/rmv.70070. Rev Med Virol. 2025. PMID: 40944962 Review.
PCVS may present as recognized diagnoses such as postural orthostatic tachycardia syndrome (POTS), small-fibre neuropathy (SFN), myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), or as long-term sequelae of myocarditis, vaccine-induced throm …
PCVS may present as recognized diagnoses such as postural orthostatic tachycardia syndrome (POTS), small-fibre neuro …
Internal Tremor in Long COVID May Be a Symptom of Dysautonomia and Small Fiber Neuropathy.
Blitshteyn S, Ruhoy IS, Natbony LR, Saperstein DS. Blitshteyn S, et al. Neurol Int. 2024 Dec 25;17(1):2. doi: 10.3390/neurolint17010002. Neurol Int. 2024. PMID: 39852767 Free PMC article.
Methods: We describe a patient with Long COVID who experienced IT as part of post-COVID postural orthostatic tachycardia syndrome (POTS) and small fiber neuropathy (SFN) and review the limited literature available on this topic. Results: Our patient's …
Methods: We describe a patient with Long COVID who experienced IT as part of post-COVID postural orthostatic tachycardia syndrome (POTS …
Corneal Confocal Microscopy in Postural Orthostatic Tachycardia Syndrome (POTS) as a Diagnostic Tool for Small Fiber Neuropathy.
Cantrell C, Rilinger R, Stallkamp Tidd SJ, Wilson R. Cantrell C, et al. Cureus. 2025 Apr 22;17(4):e82781. doi: 10.7759/cureus.82781. eCollection 2025 Apr. Cureus. 2025. PMID: 40271232 Free PMC article.
The neuropathic symptoms of POTS may be caused by small fiber neuropathy (SFN), which is currently diagnosed using skin nerve biopsy. ...Our study aimed to determine whether CCM could detect differences in small nerve fiber parameters bet …
The neuropathic symptoms of POTS may be caused by small fiber neuropathy (SFN), which is currently diagnosed usi …
Nonregional small fibre neuropathy in cases of autoimmune autonomic neuropathy.
Maier A, Kapfenberger R, Katona I, Weis J, Schulz JB, Rolke R. Maier A, et al. J Neurol. 2022 Dec;269(12):6648-6654. doi: 10.1007/s00415-022-11340-3. Epub 2022 Sep 9. J Neurol. 2022. PMID: 36085427 Free PMC article.
OBJECTIVE: Autonomic small fibre neuropathy is described in patients with autoimmune autonomic neuropathy (AAN). ...INTERPRETATION: Findings are consistent with a sensory small fibre more than large fibre neuropathy in AAN. Sensory loss w …
OBJECTIVE: Autonomic small fibre neuropathy is described in patients with autoimmune autonomic neuropathy (AAN). …
47 results