Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach.
Tosi GM, Trimarchi C, Macaluso M, La Sala D, Ciccodicola A, Lazzi S, Massaro-Giordano M, Caporossi A, Giordano A, Cinti C.
Tosi GM, et al.
Oncogene. 2005 Sep 1;24(38):5827-36. doi: 10.1038/sj.onc.1208630.
Oncogene. 2005.
PMID: 16007224
We have recently reported that loss of expression of the retinoblastoma-related protein pRb2/p130 correlates with low apoptotic index, suggesting that RB2/p130 gene could be involved in retinoblastoma. Mutational analysis of RB2/p130 in primary tumors showed a tight correl …
We have recently reported that loss of expression of the retinoblastoma-related protein pRb2/p130 correlates with low apoptotic index …