Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2008 1
2010 1
2011 1
2012 2
2013 5
2014 4
2015 1
2016 3
2017 5
2018 9
2019 8
2020 12
2021 16
2022 14
2023 14
2024 24
2025 20
2026 13

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

133 results

Results by year

Filters applied: . Clear all
Page 1
MDMA-assisted psychotherapy for PTSD in adolescents: rationale, potential, risks, and considerations.
Kangaslampi S, Zijlmans J. Kangaslampi S, et al. Eur Child Adolesc Psychiatry. 2024 Nov;33(11):3753-3764. doi: 10.1007/s00787-023-02310-9. Epub 2023 Oct 10. Eur Child Adolesc Psychiatry. 2024. PMID: 37814082 Free PMC article. Review.
3,4-Methylenedioxymetamphetamine(MDMA)-assisted psychotherapy (MDMA-AP) is a proposed treatment for posttraumatic stress disorder (PTSD) that may be approved for adults soon. PTSD is also common among trauma-exposed adolescents, and curre …
3,4-Methylenedioxymetamphetamine(MDMA)-assisted psychotherapy (MDMA-AP) is a proposed treatment for posttraumatic st …
MDMA-assisted psychotherapy for the treatment of PTSD: A systematic review and meta-analysis of randomized controlled trials (RCTs).
Shahrour G, Sohail K, Elrais S, Khan MH, Javeid J, Samdani K, Mansoor H, Hussain SI, Sharma D, Ehsan M, Nashwan AJ. Shahrour G, et al. Neuropsychopharmacol Rep. 2024 Dec;44(4):672-681. doi: 10.1002/npr2.12485. Epub 2024 Oct 9. Neuropsychopharmacol Rep. 2024. PMID: 39381877 Free PMC article.
BACKGROUND: Post-traumatic stress disorder (PTSD) is a mental health disorder resulting from exposure to traumatic events, manifesting in various debilitating symptoms. ...Previous reviews suggest promising outcomes with MDMA-assisted …
BACKGROUND: Post-traumatic stress disorder (PTSD) is a mental health disorder resulting from exposure to traumat …
MDMA-assisted psychotherapy for PTSD: Growing evidence for memory effects mediating treatment efficacy.
Sarmanlu M, Kuypers KPC, Vizeli P, Kvamme TL. Sarmanlu M, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Jan 10;128:110843. doi: 10.1016/j.pnpbp.2023.110843. Epub 2023 Aug 21. Prog Neuropsychopharmacol Biol Psychiatry. 2024. PMID: 37611653 Free article. Review.
The application of MDMA in conjunction with psychotherapy has in recent years seen a resurgence of clinical, scientific, and public interest in the treatment of posttraumatic stress disorder (PTSD). ...We review data on the effects of MDMA on fear extinction …
The application of MDMA in conjunction with psychotherapy has in recent years seen a resurgence of clinical, scientific, and public i …
MDMA-Assisted Psychotherapy for PTSD: A Systematic Review of Randomized Control Trials.
Brett B, Bynum C. Brett B, et al. J Psychoactive Drugs. 2025 Nov 5:1-13. doi: 10.1080/02791072.2025.2577308. Online ahead of print. J Psychoactive Drugs. 2025. PMID: 41190692 Review.
Posttraumatic stress disorder (PTSD) is a serious and chronic mental health condition with limited effective treatment options. 3,4-methylenedioxymethamphethamine (MDMA)-assisted psychotherapy (MDMA-AT) has shown promise in phase 2 and phase 3 c …
Posttraumatic stress disorder (PTSD) is a serious and chronic mental health condition with limited effective treatment options …
MDMA and MDMA-Assisted Therapy.
Wolfgang AS, Fonzo GA, Gray JC, Krystal JH, Grzenda A, Widge AS, Kraguljac NV, McDonald WM, Rodriguez CI, Nemeroff CB. Wolfgang AS, et al. Am J Psychiatry. 2025 Jan 1;182(1):79-103. doi: 10.1176/appi.ajp.20230681. Am J Psychiatry. 2025. PMID: 39741438 Review.
The Food and Drug Administration (FDA) designated MDMA-Assisted Therapy (MDMA-AT) as a Breakthrough Therapy for posttraumatic stress disorder (PTSD) in 2017, and the FDA is requiring an additional phase 3 trial after rejecting the initial New Drug Appl …
The Food and Drug Administration (FDA) designated MDMA-Assisted Therapy (MDMA-AT) as a Breakthrough Therapy for posttraumatic …
MDMA-assisted psychotherapy for PTSD: Are memory reconsolidation and fear extinction underlying mechanisms?
Feduccia AA, Mithoefer MC. Feduccia AA, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):221-228. doi: 10.1016/j.pnpbp.2018.03.003. Epub 2018 Mar 7. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29524515 Free article. Review.
MDMA-assisted psychotherapy for treatment of PTSD has recently progressed to Phase 3 clinical trials and received Breakthrough Therapy designation by the FDA. ...The underlying psychological and neurological mechanisms for the robust effects in mitigat …
MDMA-assisted psychotherapy for treatment of PTSD has recently progressed to Phase 3 clinical trials and receive …
MDMA-assisted psychotherapy for the treatment of PTSD.
Reiff CM, McDonald WM. Reiff CM, et al. Braz J Psychiatry. 2021 Mar-Apr;43(2):123-124. doi: 10.1590/1516-4446-2020-0020. Braz J Psychiatry. 2021. PMID: 33053043 Free PMC article. No abstract available.
MDMA-Assisted Psychotherapy for Treatment of Posttraumatic Stress Disorder: A Systematic Review With Meta-Analysis.
Smith KW, Sicignano DJ, Hernandez AV, White CM. Smith KW, et al. J Clin Pharmacol. 2022 Apr;62(4):463-471. doi: 10.1002/jcph.1995. Epub 2021 Nov 28. J Clin Pharmacol. 2022. PMID: 34708874
This article discusses current literature on the use of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in the treatment of posttraumatic stress disorder (PTSD). ...The dosing of MDMA is used to allow the therapist to probe the u …
This article discusses current literature on the use of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy …
MDMA-assisted psychotherapy for people diagnosed with treatment-resistant PTSD: what it is and what it isn't.
Morgan L. Morgan L. Ann Gen Psychiatry. 2020 May 12;19:33. doi: 10.1186/s12991-020-00283-6. eCollection 2020. Ann Gen Psychiatry. 2020. PMID: 32435270 Free PMC article. Review.
One novel approach is MDMA-assisted psychotherapy for people diagnosed with treatment-resistant PTSD, where MDMA is used as a catalyst to facilitate trauma processing during psychotherapy. The aim was to review all current research into MDMA …
One novel approach is MDMA-assisted psychotherapy for people diagnosed with treatment-resistant PTSD, where MDMA …
Effects of MDMA-assisted therapy for PTSD on self-experience.
van der Kolk BA, Wang JB, Yehuda R, Bedrosian L, Coker AR, Harrison C, Mithoefer M, Yazar-Klosinki B, Emerson A, Doblin R. van der Kolk BA, et al. PLoS One. 2024 Jan 10;19(1):e0295926. doi: 10.1371/journal.pone.0295926. eCollection 2024. PLoS One. 2024. PMID: 38198456 Free PMC article. Clinical Trial.
Primary findings from our randomized, double-blind, placebo-controlled, multi-site Phase 3 clinical trial of participants with severe PTSD (NCT03537014) showed that MDMA-assisted therapy induced significant attenuation in the Clinician-Administered PTSD …
Primary findings from our randomized, double-blind, placebo-controlled, multi-site Phase 3 clinical trial of participants with severe PTS …
133 results