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Lipid peroxidation causes endosomal antigen release for cross-presentation.
Dingjan I, Verboogen DR, Paardekooper LM, Revelo NH, Sittig SP, Visser LJ, Mollard GF, Henriet SS, Figdor CG, Ter Beest M, van den Bogaart G. Dingjan I, et al. Among authors: paardekooper lm. Sci Rep. 2016 Feb 24;6:22064. doi: 10.1038/srep22064. Sci Rep. 2016. PMID: 26907999 Free PMC article.
VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release.
Dingjan I, Paardekooper LM, Verboogen DRJ, von Mollard GF, Ter Beest M, van den Bogaart G. Dingjan I, et al. Among authors: paardekooper lm. Eur J Cell Biol. 2017 Oct;96(7):705-714. doi: 10.1016/j.ejcb.2017.06.007. Epub 2017 Jun 23. Eur J Cell Biol. 2017. PMID: 28688576 Free PMC article.
Ethylene, an early marker of systemic inflammation in humans.
Paardekooper LM, van den Bogaart G, Kox M, Dingjan I, Neerincx AH, Bendix MB, Beest MT, Harren FJM, Risby T, Pickkers P, Marczin N, Cristescu SM. Paardekooper LM, et al. Sci Rep. 2017 Jul 31;7(1):6889. doi: 10.1038/s41598-017-05930-9. Sci Rep. 2017. PMID: 28761087 Free PMC article.