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Age-related reduction in glucose elimination is accompanied by reduced glucose effectiveness and increased hepatic insulin extraction in man.
Ahrén B, Pacini G. Ahrén B, et al. Among authors: pacini g. J Clin Endocrinol Metab. 1998 Sep;83(9):3350-6. doi: 10.1210/jcem.83.9.5107. J Clin Endocrinol Metab. 1998. PMID: 9745453
Amino Acid and Fatty Acid Levels Affect Hepatic Phosphorus Metabolite Content in Metabolically Healthy Humans.
Kahl S, Nowotny B, Strassburger K, Bierwagen A, Klüppelholz B, Hoffmann B, Giani G, Nowotny PJ, Wallscheid F, Hatziagelaki E, Pacini G, Hwang JH, Roden M. Kahl S, et al. Among authors: pacini g. J Clin Endocrinol Metab. 2018 Feb 1;103(2):460-468. doi: 10.1210/jc.2017-01773. J Clin Endocrinol Metab. 2018. PMID: 29140513
Effect of single-dose DPP-4 inhibitor sitagliptin on β-cell function and incretin hormone secretion after meal ingestion in healthy volunteers and drug-naïve, well-controlled type 2 diabetes subjects.
Alsalim W, Göransson O, Carr RD, Bizzotto R, Tura A, Pacini G, Mari A, Ahrén B. Alsalim W, et al. Among authors: pacini g. Diabetes Obes Metab. 2018 Apr;20(4):1080-1085. doi: 10.1111/dom.13192. Epub 2018 Jan 16. Diabetes Obes Metab. 2018. PMID: 29227575
Circulating triacylglycerols but not pancreatic fat associate with insulin secretion in healthy humans.
Nowotny B, Kahl S, Klüppelholz B, Hoffmann B, Giani G, Livingstone R, Nowotny PJ, Stamm V, Herder C, Tura A, Pacini G, Hwang JH, Roden M. Nowotny B, et al. Among authors: pacini g. Metabolism. 2018 Apr;81:113-125. doi: 10.1016/j.metabol.2017.12.005. Epub 2017 Dec 19. Metabolism. 2018. PMID: 29273469
Glucagon increases insulin levels by stimulating insulin secretion without effect on insulin clearance in mice.
Song G, Pacini G, Ahrén B, D'Argenio DZ. Song G, et al. Among authors: pacini g. Peptides. 2017 Feb;88:74-79. doi: 10.1016/j.peptides.2016.12.012. Epub 2016 Dec 21. Peptides. 2017. PMID: 28012858 Free PMC article.
Increased insulin clearance in mice with double deletion of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors.
Tura A, Bizzotto R, Yamada Y, Seino Y, Pacini G, Ahrén B. Tura A, et al. Among authors: pacini g. Am J Physiol Regul Integr Comp Physiol. 2018 May 1;314(5):R639-R646. doi: 10.1152/ajpregu.00181.2017. Epub 2018 Jan 3. Am J Physiol Regul Integr Comp Physiol. 2018. PMID: 29351421
Evidence for neural contribution to islet effects of DPP-4 inhibition in mice.
Ahlkvist L, Omar B, Pacini G, Ahrén B. Ahlkvist L, et al. Among authors: pacini g. Eur J Pharmacol. 2016 Jun 5;780:46-52. doi: 10.1016/j.ejphar.2016.03.030. Epub 2016 Mar 17. Eur J Pharmacol. 2016. PMID: 26997369
A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs.
Jönsson T, Ahrén B, Pacini G, Sundler F, Wierup N, Steen S, Sjöberg T, Ugander M, Frostegård J, Göransson L, Lindeberg S. Jönsson T, et al. Among authors: pacini g. Nutr Metab (Lond). 2006 Nov 2;3:39. doi: 10.1186/1743-7075-3-39. Nutr Metab (Lond). 2006. PMID: 17081292 Free PMC article.
The augmenting effect on insulin secretion by oral versus intravenous glucose is exaggerated by high-fat diet in mice.
Ahrén B, Winzell MS, Pacini G. Ahrén B, et al. Among authors: pacini g. J Endocrinol. 2008 Apr;197(1):181-7. doi: 10.1677/JOE-07-0460. J Endocrinol. 2008. PMID: 18372244
Effects of smoking cessation on β-cell function, insulin sensitivity, body weight, and appetite.
Stadler M, Tomann L, Storka A, Wolzt M, Peric S, Bieglmayer C, Pacini G, Dickson SL, Brath H, Bech P, Prager R, Korbonits M. Stadler M, et al. Among authors: pacini g. Eur J Endocrinol. 2014 Feb 1;170(2):219-7. doi: 10.1530/EJE-13-0590. Print 2014 Feb. Eur J Endocrinol. 2014. PMID: 24179100
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