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New protein engineering approaches to multivalent and bispecific antibody fragments.
Plückthun A, Pack P. Plückthun A, et al. Among authors: pack p. Immunotechnology. 1997 Jun;3(2):83-105. doi: 10.1016/s1380-2933(97)00067-5. Immunotechnology. 1997. PMID: 9237094 Review.
Multivalent antibody fragments with high functional affinity for a tumor-associated carbohydrate antigen.
Rheinnecker M, Hardt C, Ilag LL, Kufer P, Gruber R, Hoess A, Lupas A, Rottenberger C, Plückthun A, Pack P. Rheinnecker M, et al. Among authors: pack p. J Immunol. 1996 Oct 1;157(7):2989-97. J Immunol. 1996. PMID: 8816407
Tetravalent miniantibodies with high avidity assembling in Escherichia coli.
Pack P, Müller K, Zahn R, Plückthun A. Pack P, et al. J Mol Biol. 1995 Feb 10;246(1):28-34. doi: 10.1006/jmbi.1994.0062. J Mol Biol. 1995. PMID: 7853401
Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli.
Pack P, Kujau M, Schroeckh V, Knüpfer U, Wenderoth R, Riesenberg D, Plückthun A. Pack P, et al. Biotechnology (N Y). 1993 Nov;11(11):1271-7. doi: 10.1038/nbt1193-1271. Biotechnology (N Y). 1993. PMID: 7764189
High-throughput generation and engineering of recombinant human antibodies.
Krebs B, Rauchenberger R, Reiffert S, Rothe C, Tesar M, Thomassen E, Cao M, Dreier T, Fischer D, Höss A, Inge L, Knappik A, Marget M, Pack P, Meng XQ, Schier R, Söhlemann P, Winter J, Wölle J, Kretzschmar T. Krebs B, et al. Among authors: pack p. J Immunol Methods. 2001 Aug 1;254(1-2):67-84. doi: 10.1016/s0022-1759(01)00398-2. J Immunol Methods. 2001. PMID: 11406154
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides.
Knappik A, Ge L, Honegger A, Pack P, Fischer M, Wellnhofer G, Hoess A, Wölle J, Plückthun A, Virnekäs B. Knappik A, et al. Among authors: pack p. J Mol Biol. 2000 Feb 11;296(1):57-86. doi: 10.1006/jmbi.1999.3444. J Mol Biol. 2000. PMID: 10656818
New Technique: Acute Minced Expansion Graft of Traumatic Wound Tissue.
Klapper AM, Moradian S, Pack P. Klapper AM, et al. Among authors: pack p. Adv Skin Wound Care. 2016 Dec;29(12):540-545. doi: 10.1097/01.ASW.0000499866.27975.28. Adv Skin Wound Care. 2016. PMID: 27846027