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PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
Zhang Y, Mao D, Roswit WT, Jin X, Patel AC, Patel DA, Agapov E, Wang Z, Tidwell RM, Atkinson JJ, Huang G, McCarthy R, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ. Zhang Y, et al. Among authors: paessler s. Nat Immunol. 2015 Dec;16(12):1215-27. doi: 10.1038/ni.3279. Epub 2015 Oct 19. Nat Immunol. 2015. PMID: 26479788 Free PMC article.
Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1).
Yun NE, Linde NS, Zacks MA, Barr IG, Hurt AC, Smith JN, Dziuba N, Holbrook MR, Zhang L, Kilpatrick JM, Arnold CS, Paessler S. Yun NE, et al. Among authors: paessler s. Virology. 2008 Apr 25;374(1):198-209. doi: 10.1016/j.virol.2007.12.029. Epub 2008 Jan 29. Virology. 2008. PMID: 18234269 Free PMC article.
Effect of ribavirin on junin virus infection in guinea pigs.
Salazar M, Yun NE, Poussard AL, Smith JN, Smith JK, Kolokoltsova OA, Patterson MJ, Linde J, Paessler S. Salazar M, et al. Among authors: paessler s. Zoonoses Public Health. 2012 Jun;59(4):278-85. doi: 10.1111/j.1863-2378.2011.01447.x. Epub 2012 Jan 2. Zoonoses Public Health. 2012. PMID: 22212688
162 results