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N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.
Wei Z, Yang H, Liu Z, Tremblay M, Johnstone S, Béha S, Yue SY, Srivastava S, Tomaszewski MJ, Brown W, Walpole C, St-Onge S, Lessard E, Archambault AJ, Groblewski T, Pagé D. Wei Z, et al. Among authors: page d. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3884-9. doi: 10.1016/j.bmcl.2012.04.128. Epub 2012 May 4. Bioorg Med Chem Lett. 2012. PMID: 22607668
Novel benzimidazole derivatives as selective CB2 agonists.
Pagé D, Balaux E, Boisvert L, Liu Z, Milburn C, Tremblay M, Wei Z, Woo S, Luo X, Cheng YX, Yang H, Srivastava S, Zhou F, Brown W, Tomaszewski M, Walpole C, Hodzic L, St-Onge S, Godbout C, Salois D, Payza K. Pagé D, et al. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3695-700. doi: 10.1016/j.bmcl.2008.05.073. Epub 2008 May 22. Bioorg Med Chem Lett. 2008. PMID: 18522867
New scaffolds in the development of mu opioid-receptor ligands.
Pagé D, Nguyen N, Bernard S, Coupal M, Gosselin M, Lepage J, Adam L, Brown W. Pagé D, et al. Bioorg Med Chem Lett. 2003 May 5;13(9):1585-9. doi: 10.1016/s0960-894x(03)00194-x. Bioorg Med Chem Lett. 2003. PMID: 12699761
Synthesis and biological properties of mannosylated starburst poly(amidoamine) dendrimers.
Pagé D, Roy R. Pagé D, et al. Bioconjug Chem. 1997 Sep-Oct;8(5):714-23. doi: 10.1021/bc970126u. Bioconjug Chem. 1997. PMID: 9327136
These mannosylated dendrimers were demonstrated to be potent inhibitors with IC50 values 400 times better than those of monomeric methyl alpha-D-mannopyranoside taken as a standard. Their lipophilic character was shown to be sufficient for their direct use as coating antig …
These mannosylated dendrimers were demonstrated to be potent inhibitors with IC50 values 400 times better than those of monomeric methyl alp …
1,364 results