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Toxin-antitoxin systems in bacterial growth arrest and persistence.
Page R, Peti W. Page R, et al. Nat Chem Biol. 2016 Apr;12(4):208-14. doi: 10.1038/nchembio.2044. Nat Chem Biol. 2016. PMID: 26991085 Review.
Human alpha-defensins inhibit BK virus infection by aggregating virions and blocking binding to host cells.
Dugan AS, Maginnis MS, Jordan JA, Gasparovic ML, Manley K, Page R, Williams G, Porter E, O'Hara BA, Atwood WJ. Dugan AS, et al. J Biol Chem. 2008 Nov 7;283(45):31125-32. doi: 10.1074/jbc.M805902200. Epub 2008 Sep 9. J Biol Chem. 2008. PMID: 18782756 Free PMC article.
Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors.
Kelker MS, Page R, Peti W. Kelker MS, et al. J Mol Biol. 2009 Jan 9;385(1):11-21. doi: 10.1016/j.jmb.2008.10.053. Epub 2008 Nov 1. J Mol Biol. 2009. PMID: 18992256 Free PMC article.
We report the crystal structures of PP1 in complex with nodularin-R at 1.63 A and tautomycin at 1.70 A resolution. The PP1:nodularin-R complex was used to demonstrate the utility of our improved PP1 production technique, which produces highly active, soluble PP1. .. …
We report the crystal structures of PP1 in complex with nodularin-R at 1.63 A and tautomycin at 1.70 A resolution. The PP1:nodularin- …
Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Ragusa MJ, Dancheck B, Critton DA, Nairn AC, Page R, Peti W. Ragusa MJ, et al. Nat Struct Mol Biol. 2010 Apr;17(4):459-64. doi: 10.1038/nsmb.1786. Epub 2010 Mar 21. Nat Struct Mol Biol. 2010. PMID: 20305656 Free PMC article.
Strategies to optimize protein expression in E. coli.
Francis DM, Page R. Francis DM, et al. Curr Protoc Protein Sci. 2010 Aug;Chapter 5(1):Unit 5.24.1-29. doi: 10.1002/0471140864.ps0524s61. Curr Protoc Protein Sci. 2010. PMID: 20814932 Free PMC article. Review.
Preliminary crystallographic analysis of the Escherichia coli antitoxin MqsA (YgiT/b3021) in complex with mqsRA promoter DNA.
Brown BL, Page R. Brown BL, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt 9):1060-3. doi: 10.1107/S1744309110028617. Epub 2010 Aug 26. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20823526 Free PMC article.
Structure of the Escherichia coli antitoxin MqsA (YgiT/b3021) bound to its gene promoter reveals extensive domain rearrangements and the specificity of transcriptional regulation.
Brown BL, Wood TK, Peti W, Page R. Brown BL, et al. J Biol Chem. 2011 Jan 21;286(3):2285-96. doi: 10.1074/jbc.M110.172643. Epub 2010 Nov 9. J Biol Chem. 2011. PMID: 21068382 Free PMC article.
Resting and active states of the ERK2:HePTP complex.
Francis DM, Różycki B, Tortajada A, Hummer G, Peti W, Page R. Francis DM, et al. J Am Chem Soc. 2011 Nov 2;133(43):17138-41. doi: 10.1021/ja2075136. Epub 2011 Oct 10. J Am Chem Soc. 2011. PMID: 21985012 Free PMC article.
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