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Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice.
Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG. Vegas AJ, et al. Among authors: pagliuca fw. Nat Med. 2016 Mar;22(3):306-11. doi: 10.1038/nm.4030. Epub 2016 Jan 25. Nat Med. 2016. PMID: 26808346 Free PMC article.
How to make a functional β-cell.
Pagliuca FW, Melton DA. Pagliuca FW, et al. Development. 2013 Jun;140(12):2472-83. doi: 10.1242/dev.093187. Development. 2013. PMID: 23715541 Free PMC article. Review.
Generation of functional human pancreatic β cells in vitro.
Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA. Pagliuca FW, et al. Cell. 2014 Oct 9;159(2):428-39. doi: 10.1016/j.cell.2014.09.040. Cell. 2014. PMID: 25303535 Free PMC article.
Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice.
Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG. Vegas AJ, et al. Among authors: pagliuca fw. Nat Med. 2016 Apr;22(4):446. doi: 10.1038/nm0416-446e. Nat Med. 2016. PMID: 27050590 No abstract available.
A simple tool to improve pluripotent stem cell differentiation.
Chetty S, Pagliuca FW, Honore C, Kweudjeu A, Rezania A, Melton DA. Chetty S, et al. Among authors: pagliuca fw. Nat Methods. 2013 Jun;10(6):553-6. doi: 10.1038/nmeth.2442. Epub 2013 Apr 14. Nat Methods. 2013. PMID: 23584186 Free PMC article.
Charting cellular identity during human in vitro β-cell differentiation.
Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA. Veres A, et al. Among authors: pagliuca fw. Nature. 2019 May;569(7756):368-373. doi: 10.1038/s41586-019-1168-5. Epub 2019 May 8. Nature. 2019. PMID: 31068696 Free PMC article.
Differentiated human stem cells resemble fetal, not adult, β cells.
Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FW, DiIorio P, Rezania A, Gifford DK, Melton DA. Hrvatin S, et al. Among authors: pagliuca fw. Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3038-43. doi: 10.1073/pnas.1400709111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516164 Free PMC article.
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