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Immunotoxin therapy for cancer.
Pai LH, Pastan I. Pai LH, et al. JAMA. 1993 Jan 6;269(1):78-81. JAMA. 1993. PMID: 8416411 Review. No abstract available.
Relationship between patient response in ovarian and breast cancer and platinum drug-DNA adduct formation.
Gupta-Burt S, Shamkhani H, Reed E, Tarone RE, Allegra CJ, Pai LH, Poirier MC. Gupta-Burt S, et al. Among authors: pai lh. Cancer Epidemiol Biomarkers Prev. 1993 May-Jun;2(3):229-34. Cancer Epidemiol Biomarkers Prev. 1993. PMID: 8318875
Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium.
Chang K, Pai LH, Batra JK, Pastan I, Willingham MC. Chang K, et al. Among authors: pai lh. Cancer Res. 1992 Jan 1;52(1):181-6. Cancer Res. 1992. PMID: 1727378
Efficacy of compartmental administration of immunotoxin LMB-1 (B3-LysPE38) in a rat model of carcinomatous meningitis.
Bigner DD, Archer GE, McLendon RE, Friedman HS, Fuchs HE, Pai LH, Herndon JE 2nd, Pastan IH. Bigner DD, et al. Among authors: pai lh. Clin Cancer Res. 1995 Dec;1(12):1545-55. Clin Cancer Res. 1995. PMID: 9815955 Free article.
Immunotoxins containing Pseudomonas exotoxin that target LeY damage human endothelial cells in an antibody-specific mode: relevance to vascular leak syndrome.
Kuan CT, Pai LH, Pastan I. Kuan CT, et al. Among authors: pai lh. Clin Cancer Res. 1995 Dec;1(12):1589-94. Clin Cancer Res. 1995. PMID: 9815960 Free article.
Clinical trials with Pseudomonas exotoxin immunotoxins.
Pai LH, Pastan I. Pai LH, et al. Curr Top Microbiol Immunol. 1998;234:83-96. doi: 10.1007/978-3-642-72153-3_6. Curr Top Microbiol Immunol. 1998. PMID: 9670614 No abstract available.
Identification of epitopes on a mutant form of Pseudomonas exotoxin using serum from humans treated with Pseudomonas exotoxin containing immunotoxins.
Roscoe DM, Pai LH, Pastan I. Roscoe DM, et al. Among authors: pai lh. Eur J Immunol. 1997 Jun;27(6):1459-68. doi: 10.1002/eji.1830270624. Eur J Immunol. 1997. PMID: 9209499 Clinical Trial.
Recombinant immunotoxins.
Pastan I, Pai LH, Brinkmann U, FitzGerald D. Pastan I, et al. Among authors: pai lh. Breast Cancer Res Treat. 1996;38(1):3-9. doi: 10.1007/BF01803778. Breast Cancer Res Treat. 1996. PMID: 8825117 Review.
Treatment of advanced solid tumors with immunotoxin LMB-1: an antibody linked to Pseudomonas exotoxin.
Pai LH, Wittes R, Setser A, Willingham MC, Pastan I. Pai LH, et al. Nat Med. 1996 Mar;2(3):350-3. doi: 10.1038/nm0396-350. Nat Med. 1996. PMID: 8612238 Clinical Trial.
Pseudomonas exotoxin conjugated to monoclonal antibody MRK16 specifically kills multidrug resistant cells in cultured renal carcinomas and in MDR-transgenic mice.
Mickisch GH, Pai LH, Siegsmund M, Campain J, Gottesman MM, Pastan I. Mickisch GH, et al. Among authors: pai lh. J Urol. 1993 Jan;149(1):174-8. doi: 10.1016/s0022-5347(17)36033-0. J Urol. 1993. PMID: 8417204
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