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Notch signaling in mammalian hematopoietic stem cells.
Pajcini KV, Speck NA, Pear WS. Pajcini KV, et al. Leukemia. 2011 Oct;25(10):1525-32. doi: 10.1038/leu.2011.127. Epub 2011 Jun 7. Leukemia. 2011. PMID: 21647159 Free PMC article. Review.
The Notch1 transcriptional activation domain is required for development and reveals a novel role for Notch1 signaling in fetal hematopoietic stem cells.
Gerhardt DM, Pajcini KV, D'altri T, Tu L, Jain R, Xu L, Chen MJ, Rentschler S, Shestova O, Wertheim GB, Tobias JW, Kluk M, Wood AW, Aster JC, Gimotty PA, Epstein JA, Speck N, Bigas A, Pear WS. Gerhardt DM, et al. Genes Dev. 2014 Mar 15;28(6):576-93. doi: 10.1101/gad.227496.113. Genes Dev. 2014. PMID: 24637115 Free PMC article.
Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL.
Stein SJ, Mack EA, Rome KS, Pajcini KV, Ohtani T, Xu L, Li Y, Meijerink JP, Faryabi RB, Pear WS. Stein SJ, et al. PLoS One. 2016 May 18;11(5):e0155408. doi: 10.1371/journal.pone.0155408. eCollection 2016. PLoS One. 2016. PMID: 27191957 Free PMC article.
Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand.
Greene M, Lai Y, Pajcini K, Bailis W, Pear WS, Lancaster E. Greene M, et al. Among authors: pajcini k. PLoS One. 2016 Sep 13;11(9):e0161157. doi: 10.1371/journal.pone.0161157. eCollection 2016. PLoS One. 2016. PMID: 27622512 Free PMC article.
MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
Pajcini KV, Xu L, Shao L, Petrovic J, Palasiewicz K, Ohtani Y, Bailis W, Lee C, Wertheim GB, Mani R, Muthusamy N, Li Y, Meijerink JPP, Blacklow SC, Faryabi RB, Cherry S, Pear WS. Pajcini KV, et al. Sci Signal. 2017 Nov 14;10(505):eaam6846. doi: 10.1126/scisignal.aam6846. Sci Signal. 2017. PMID: 29138297 Free PMC article.
Notch Signaling in the Bone Marrow Lymphopoietic Niche.
Sottoriva K, Pajcini KV. Sottoriva K, et al. Among authors: pajcini kv. Front Immunol. 2021 Jul 28;12:723055. doi: 10.3389/fimmu.2021.723055. eCollection 2021. Front Immunol. 2021. PMID: 34394130 Free PMC article. Review.
A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche.
Shao L, Sottoriva K, Palasiewicz K, Zhang J, Hyun J, Soni SS, Paik NY, Gao X, Cuervo H, Malik AB, Rehman J, Lucas D, Pajcini KV. Shao L, et al. Among authors: pajcini kv. Haematologica. 2019 Nov;104(11):2164-2177. doi: 10.3324/haematol.2018.208660. Epub 2019 Mar 28. Haematologica. 2019. PMID: 30923091 Free PMC article.
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