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The small SLC43 family: facilitator system l amino acid transporters and the orphan EEG1.
Bodoy S, Fotiadis D, Stoeger C, Kanai Y, Palacín M. Bodoy S, et al. Among authors: palacin m. Mol Aspects Med. 2013 Apr-Jun;34(2-3):638-45. doi: 10.1016/j.mam.2012.12.006. Epub 2012 Dec 23. Mol Aspects Med. 2013. PMID: 23268354 Review.
Molecular basis of substrate-induced permeation by an amino acid antiporter.
Kowalczyk L, Ratera M, Paladino A, Bartoccioni P, Errasti-Murugarren E, Valencia E, Portella G, Bial S, Zorzano A, Fita I, Orozco M, Carpena X, Vázquez-Ibar JL, Palacín M. Kowalczyk L, et al. Among authors: palacin m. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):3935-40. doi: 10.1073/pnas.1018081108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368142 Free PMC article.
Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability.
de la Ballina LR, Cano-Crespo S, González-Muñoz E, Bial S, Estrach S, Cailleteau L, Tissot F, Daniel H, Zorzano A, Ginsberg MH, Palacín M, Féral CC. de la Ballina LR, et al. Among authors: palacin m. J Biol Chem. 2016 Apr 29;291(18):9700-11. doi: 10.1074/jbc.M115.704254. Epub 2016 Mar 5. J Biol Chem. 2016. PMID: 26945935 Free PMC article.
Functional and structural characterization of the first prokaryotic member of the L-amino acid transporter (LAT) family: a model for APC transporters.
Reig N, del Rio C, Casagrande F, Ratera M, Gelpí JL, Torrents D, Henderson PJ, Xie H, Baldwin SA, Zorzano A, Fotiadis D, Palacín M. Reig N, et al. Among authors: palacin m. J Biol Chem. 2007 May 4;282(18):13270-81. doi: 10.1074/jbc.M610695200. Epub 2007 Mar 6. J Biol Chem. 2007. PMID: 17344220
Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.
Fernández E, Torrents D, Zorzano A, Palacín M, Chillarón J. Fernández E, et al. Among authors: palacin m. J Biol Chem. 2005 May 13;280(19):19364-72. doi: 10.1074/jbc.M412516200. Epub 2005 Mar 9. J Biol Chem. 2005. PMID: 15757906
Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth.
Cormerais Y, Giuliano S, LeFloch R, Front B, Durivault J, Tambutté E, Massard PA, de la Ballina LR, Endou H, Wempe MF, Palacin M, Parks SK, Pouyssegur J. Cormerais Y, et al. Among authors: palacin m. Cancer Res. 2016 Aug 1;76(15):4481-92. doi: 10.1158/0008-5472.CAN-15-3376. Epub 2016 Jun 14. Cancer Res. 2016. PMID: 27302165
A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells.
Segalés J, Paz JC, Hernández-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacín M, Enríquez JA, Zorzano A. Segalés J, et al. Among authors: palacin m. Am J Physiol Endocrinol Metab. 2013 Nov 15;305(10):E1208-21. doi: 10.1152/ajpendo.00546.2012. Epub 2013 Aug 13. Am J Physiol Endocrinol Metab. 2013. PMID: 23941871
Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism.
Hernández-Alvarez MI, Díaz-Ramos A, Berdasco M, Cobb J, Planet E, Cooper D, Pazderska A, Wanic K, O'Hanlon D, Gomez A, de la Ballina LR, Esteller M, Palacin M, O'Gorman DJ, Nolan JJ, Zorzano A. Hernández-Alvarez MI, et al. Among authors: palacin m. Sci Rep. 2017 Oct 23;7(1):13850. doi: 10.1038/s41598-017-14120-6. Sci Rep. 2017. PMID: 29062026 Free PMC article.
Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging.
Sebastián D, Palacín M, Zorzano A. Sebastián D, et al. Among authors: palacin m. Trends Mol Med. 2017 Mar;23(3):201-215. doi: 10.1016/j.molmed.2017.01.003. Epub 2017 Feb 7. Trends Mol Med. 2017. PMID: 28188102 Review.
Detergent-induced stabilization and improved 3D map of the human heteromeric amino acid transporter 4F2hc-LAT2.
Meury M, Costa M, Harder D, Stauffer M, Jeckelmann JM, Brühlmann B, Rosell A, Ilgü H, Kovar K, Palacín M, Fotiadis D. Meury M, et al. Among authors: palacin m. PLoS One. 2014 Oct 9;9(10):e109882. doi: 10.1371/journal.pone.0109882. eCollection 2014. PLoS One. 2014. PMID: 25299125 Free PMC article.
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