Palfreyman MN - Search Results

1

Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3-(cyclopentyloxy)-4-methoxybenzamides and analogues.

Ashton MJ, Cook DC, Fenton G, Karlsson JA, Palfreyman MN, Raeburn D, Ratcliffe AJ, Souness JE, Thurairatnam S, Vicker N. Ashton MJ, et al. Among authors: palfreyman mn. J Med Chem. 1994 May 27;37(11):1696-703. doi: 10.1021/jm00037a021. J Med Chem. 1994. PMID: 8201604

2

Synthesis and biological activity of trans(+-)-N-methyl-2-(3-pyridyl)-2-tetrahydrothiopyrancarbothioamide 1-oxide (RP 49356) and analogues: a new class of potassium channel opener.

Brown TJ, Chapman RF, Cook DC, Hart TW, McLay IM, Jordan R, Mason JS, Palfreyman MN, Walsh RJ, Withnall MT, et al. Brown TJ, et al. Among authors: palfreyman mn. J Med Chem. 1992 Oct 2;35(20):3613-24. doi: 10.1021/jm00098a004. J Med Chem. 1992. PMID: 1433171

3

Syntheses and biological activities of potent potassium channel openers derived from (+/-)-2-oxo-1-pyridin-3-yl-cyclohexanecarbothioic acid methylamide: new potassium channel openers.

Brown TJ, Chapman RF, Mason JS, Palfreyman MN, Vicker N, Walsh RJ. Brown TJ, et al. Among authors: palfreyman mn. J Med Chem. 1993 May 28;36(11):1604-12. doi: 10.1021/jm00063a010. J Med Chem. 1993. PMID: 8496928

4

Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.

Souness JE, Griffin M, Maslen C, Ebsworth K, Scott LC, Pollock K, Palfreyman MN, Karlsson JA. Souness JE, et al. Among authors: palfreyman mn. Br J Pharmacol. 1996 Jun;118(3):649-58. doi: 10.1111/j.1476-5381.1996.tb15450.x. Br J Pharmacol. 1996. PMID: 8762090 Free PMC article.

5

Phosphodiesterase type IV inhibitors.

Palfreyman MN, Souness JE. Palfreyman MN, et al. Prog Med Chem. 1996;33:1-52. doi: 10.1016/s0079-6468(08)70302-3. Prog Med Chem. 1996. PMID: 8776940 Review. No abstract available.

6

Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.

Souness JE, Maslen C, Webber S, Foster M, Raeburn D, Palfreyman MN, Ashton MJ, Karlsson JA. Souness JE, et al. Among authors: palfreyman mn. Br J Pharmacol. 1995 May;115(1):39-46. doi: 10.1111/j.1476-5381.1995.tb16317.x. Br J Pharmacol. 1995. PMID: 7647982 Free PMC article.

7

Synthesis and antifertility activity of omega-chain phenyl- and 16-phenoxy-analogues of (+/-)-11-deoxyprostaglandin F1 alpha.

Broughton BJ, Caton MP, Coffee EC, Hambling DJ, Palfreyman MN, Withnall MT, Wooldridge KR. Broughton BJ, et al. Among authors: palfreyman mn. Prostaglandins. 1980 Apr;19(4):559-75. doi: 10.1016/s0090-6980(80)80006-2. Prostaglandins. 1980. PMID: 7384556

8

Uterine stimulant action of some 16-phenoxy analogues of (+)-11-deoxyprostaglandin E1.

Caton MP, Coffee EC, Hambling DJ, Hardy CJ, Palfreyman MN. Caton MP, et al. Among authors: palfreyman mn. Prostaglandins. 1984 May;27(5):761-70. doi: 10.1016/0090-6980(84)90013-3. Prostaglandins. 1984. PMID: 6463274

9

Synthesis and anti-ulcer activity of 16-phenoxy analogues of (+)-11-deoxyprostaglandin E1.

Banerjee AK, Broughton BJ, Burton TS, Caton MP, Christmas AJ, Coffee EC, Crowshaw K, Hardy CJ, Heazell MA, Palfreyman MN, Parker T, Saunders LC, Stuttle KA. Banerjee AK, et al. Among authors: palfreyman mn. Prostaglandins. 1981 Aug;22(2):167-82. doi: 10.1016/0090-6980(81)90032-0. Prostaglandins. 1981. PMID: 7291597 No abstract available.

10

Potential chemotherapeutic agents. Formation of 2,7-naphthyridones from nicotinamide derivatives.

Palfreyman MN, Wooldridge KR. Palfreyman MN, et al. J Chem Soc Perkin 1. 1974;1:57-61. doi: 10.1039/p19740000057. J Chem Soc Perkin 1. 1974. PMID: 4273812 No abstract available.

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