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Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease.
Jia H, Pallos J, Jacques V, Lau A, Tang B, Cooper A, Syed A, Purcell J, Chen Y, Sharma S, Sangrey GR, Darnell SB, Plasterer H, Sadri-Vakili G, Gottesfeld JM, Thompson LM, Rusche JR, Marsh JL, Thomas EA. Jia H, et al. Among authors: pallos j. Neurobiol Dis. 2012 May;46(2):351-61. doi: 10.1016/j.nbd.2012.01.016. Neurobiol Dis. 2012. PMID: 22590724 Free PMC article.
Fly models of Huntington's disease.
Marsh JL, Pallos J, Thompson LM. Marsh JL, et al. Among authors: pallos j. Hum Mol Genet. 2003 Oct 15;12 Spec No 2:R187-93. doi: 10.1093/hmg/ddg271. Epub 2003 Aug 12. Hum Mol Genet. 2003. PMID: 12925571 Review.
Altered protein acetylation in polyglutamine diseases.
Bodai L, Pallos J, Thompson LM, Marsh JL. Bodai L, et al. Among authors: pallos j. Curr Med Chem. 2003 Dec;10(23):2577-87. doi: 10.2174/0929867033456530. Curr Med Chem. 2003. PMID: 14529472 Review.
A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila.
Apostol BL, Kazantsev A, Raffioni S, Illes K, Pallos J, Bodai L, Slepko N, Bear JE, Gertler FB, Hersch S, Housman DE, Marsh JL, Thompson LM. Apostol BL, et al. Among authors: pallos j. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5950-5. doi: 10.1073/pnas.2628045100. Epub 2003 May 1. Proc Natl Acad Sci U S A. 2003. PMID: 12730384 Free PMC article.
SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models.
Quinti L, Casale M, Moniot S, Pais TF, Van Kanegan MJ, Kaltenbach LS, Pallos J, Lim RG, Naidu SD, Runne H, Meisel L, Rauf NA, Leyfer D, Maxwell MM, Saiah E, Landers JE, Luthi-Carter R, Abagyan R, Dinkova-Kostova AT, Steegborn C, Marsh JL, Lo DC, Thompson LM, Kazantsev AG. Quinti L, et al. Among authors: pallos j. Cell Chem Biol. 2016 Jul 21;23(7):849-861. doi: 10.1016/j.chembiol.2016.05.015. Epub 2016 Jul 14. Cell Chem Biol. 2016. PMID: 27427231 Free article.
27 results