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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 2
1973 2
1974 6
1975 5
1976 4
1977 3
1978 6
1979 4
1980 2
1981 5
1982 3
1983 6
1984 6
1985 7
1986 7
1987 6
1988 3
1989 5
1990 3
1991 4
1992 4
1993 7
1995 4
1996 7
1997 5
1998 3
1999 3
2000 2
2003 1
2004 2
2006 2
2007 1
2008 1
2010 4
2011 7
2012 4
2013 9
2014 6
2015 4
2016 4
2017 3
2018 2
2019 5
2020 0
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170 results
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Page 1
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, LeBrasseur NK, Wren JD, Farr JN, Khosla S, Stout MB, McGowan SJ, Fuhrmann-Stroissnigg H, Gurkar AU, Zhao J, Colangelo D, Dorronsoro A, Ling YY, Barghouthy AS, Navarro DC, Sano T, Robbins PD, Niedernhofer LJ, Kirkland JL. Zhu Y, et al. Among authors: Palmer AK. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25754370 Free PMC article.
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: Palmer AK. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity.
Palmer AK, Tchkonia T, LeBrasseur NK, Chini EN, Xu M, Kirkland JL. Palmer AK, et al. Diabetes. 2015 Jul;64(7):2289-98. doi: 10.2337/db14-1820. Diabetes. 2015. PMID: 26106186 Free PMC article. Review.
Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL. Palmer AK, et al. Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111/acel.12950. Epub 2019 Mar 25. Aging Cell. 2019. PMID: 30907060 Free PMC article.
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.
Ogrodnik M, Zhu Y, Langhi LGP, Tchkonia T, Kr├╝ger P, Fielder E, Victorelli S, Ruswhandi RA, Giorgadze N, Pirtskhalava T, Podgorni O, Enikolopov G, Johnson KO, Xu M, Inman C, Palmer AK, Schafer M, Weigl M, Ikeno Y, Burns TC, Passos JF, von Zglinicki T, Kirkland JL, Jurk D. Ogrodnik M, et al. Among authors: Palmer AK. Cell Metab. 2019 May 7;29(5):1061-1077.e8. doi: 10.1016/j.cmet.2018.12.008. Epub 2019 Jan 3. Cell Metab. 2019. PMID: 30612898 Free PMC article.
Cellular senescence: at the nexus between ageing and diabetes.
Palmer AK, Gustafson B, Kirkland JL, Smith U. Palmer AK, et al. Diabetologia. 2019 Oct;62(10):1835-1841. doi: 10.1007/s00125-019-4934-x. Epub 2019 Aug 27. Diabetologia. 2019. PMID: 31451866 Free PMC article. Review.
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.
Roos CM, Zhang B, Palmer AK, Ogrodnik MB, Pirtskhalava T, Thalji NM, Hagler M, Jurk D, Smith LA, Casaclang-Verzosa G, Zhu Y, Schafer MJ, Tchkonia T, Kirkland JL, Miller JD. Roos CM, et al. Among authors: Palmer AK. Aging Cell. 2016 Oct;15(5):973-7. doi: 10.1111/acel.12458. Epub 2016 Aug 5. Aging Cell. 2016. PMID: 26864908 Free PMC article.
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Schafer MJ, White TA, Evans G, Tonne JM, Verzosa GC, Stout MB, Mazula DL, Palmer AK, Baker DJ, Jensen MD, Torbenson MS, Miller JD, Ikeda Y, Tchkonia T, van Deursen JM, Kirkland JL, LeBrasseur NK. Schafer MJ, et al. Among authors: Palmer AK. Diabetes. 2016 Jun;65(6):1606-15. doi: 10.2337/db15-0291. Epub 2016 Mar 16. Diabetes. 2016. PMID: 26983960 Free PMC article.
Targeting senescent cells enhances adipogenesis and metabolic function in old age.
Xu M, Palmer AK, Ding H, Weivoda MM, Pirtskhalava T, White TA, Sepe A, Johnson KO, Stout MB, Giorgadze N, Jensen MD, LeBrasseur NK, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: Palmer AK. Elife. 2015 Dec 19;4:e12997. doi: 10.7554/eLife.12997. Elife. 2015. PMID: 26687007 Free PMC article.
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