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Increased hepatic gluconeogenesis and type 2 diabetes mellitus.
Barroso E, Jurado-Aguilar J, Wahli W, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: palomer x. Trends Endocrinol Metab. 2024 May 29:S1043-2760(24)00124-3. doi: 10.1016/j.tem.2024.05.006. Online ahead of print. Trends Endocrinol Metab. 2024. PMID: 38816269 Review.
Targeting endoplasmic reticulum stress in insulin resistance.
Salvadó L, Palomer X, Barroso E, Vázquez-Carrera M. Salvadó L, et al. Among authors: palomer x. Trends Endocrinol Metab. 2015 Aug;26(8):438-48. doi: 10.1016/j.tem.2015.05.007. Epub 2015 Jun 12. Trends Endocrinol Metab. 2015. PMID: 26078196 Review.
Knocking on GDF15's door for the treatment of type 2 diabetes mellitus.
Aguilar-Recarte D, Barroso E, Palomer X, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: palomer x. Trends Endocrinol Metab. 2022 Nov;33(11):741-754. doi: 10.1016/j.tem.2022.08.004. Epub 2022 Sep 20. Trends Endocrinol Metab. 2022. PMID: 36151002 Review.
The PPARβ/δ activator GW501516 prevents the down-regulation of AMPK caused by a high-fat diet in liver and amplifies the PGC-1α-Lipin 1-PPARα pathway leading to increased fatty acid oxidation.
Barroso E, Rodríguez-Calvo R, Serrano-Marco L, Astudillo AM, Balsinde J, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: palomer x. Endocrinology. 2011 May;152(5):1848-59. doi: 10.1210/en.2010-1468. Epub 2011 Mar 1. Endocrinology. 2011. PMID: 21363937 Free article.
Targeting PPARβ/δ for the treatment of type 2 diabetes mellitus.
Salvadó L, Serrano-Marco L, Barroso E, Palomer X, Vázquez-Carrera M. Salvadó L, et al. Among authors: palomer x. Expert Opin Ther Targets. 2012 Feb;16(2):209-23. doi: 10.1517/14728222.2012.658370. Epub 2012 Jan 27. Expert Opin Ther Targets. 2012. PMID: 22280315 Review.
Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.
Zarei M, Barroso E, Palomer X, Dai J, Rada P, Quesada-López T, Escolà-Gil JC, Cedó L, Zali MR, Molaei M, Dabiri R, Vázquez S, Pujol E, Valverde ÁM, Villarroya F, Liu Y, Wahli W, Vázquez-Carrera M. Zarei M, et al. Among authors: palomer x. Mol Metab. 2018 Feb;8:117-131. doi: 10.1016/j.molmet.2017.12.008. Epub 2017 Dec 19. Mol Metab. 2018. PMID: 29289645 Free PMC article.
The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling.
Botteri G, Salvadó L, Gumà A, Lee Hamilton D, Meakin PJ, Montagut G, Ashford MLJ, Ceperuelo-Mallafré V, Fernández-Veledo S, Vendrell J, Calderón-Dominguez M, Serra D, Herrero L, Pizarro J, Barroso E, Palomer X, Vázquez-Carrera M. Botteri G, et al. Among authors: palomer x. Metabolism. 2018 Aug;85:59-75. doi: 10.1016/j.metabol.2018.03.005. Epub 2018 Mar 9. Metabolism. 2018. PMID: 29526536 Free article.
Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.
Zarei M, Pujol E, Quesada-López T, Villarroya F, Barroso E, Vázquez S, Pizarro-Delgado J, Palomer X, Vázquez-Carrera M. Zarei M, et al. Among authors: palomer x. Br J Pharmacol. 2019 Jul;176(13):2292-2305. doi: 10.1111/bph.14678. Epub 2019 May 23. Br J Pharmacol. 2019. PMID: 30927369 Free PMC article.
77 results