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Structure and dynamics of the M3 muscarinic acetylcholine receptor.
Kruse AC, Hu J, Pan AC, Arlow DH, Rosenbaum DM, Rosemond E, Green HF, Liu T, Chae PS, Dror RO, Shaw DE, Weis WI, Wess J, Kobilka BK. Kruse AC, et al. Among authors: pan ac. Nature. 2012 Feb 22;482(7386):552-6. doi: 10.1038/nature10867. Nature. 2012. PMID: 22358844 Free PMC article.
Pathway and mechanism of drug binding to G-protein-coupled receptors.
Dror RO, Pan AC, Arlow DH, Borhani DW, Maragakis P, Shan Y, Xu H, Shaw DE. Dror RO, et al. Among authors: pan ac. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13118-23. doi: 10.1073/pnas.1104614108. Epub 2011 Jul 21. Proc Natl Acad Sci U S A. 2011. PMID: 21778406 Free PMC article.
Activation mechanism of the β2-adrenergic receptor.
Dror RO, Arlow DH, Maragakis P, Mildorf TJ, Pan AC, Xu H, Borhani DW, Shaw DE. Dror RO, et al. Among authors: pan ac. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18684-9. doi: 10.1073/pnas.1110499108. Epub 2011 Oct 26. Proc Natl Acad Sci U S A. 2011. PMID: 22031696 Free PMC article.
The dynamic process of β(2)-adrenergic receptor activation.
Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. Nygaard R, et al. Among authors: pan ac. Cell. 2013 Jan 31;152(3):532-42. doi: 10.1016/j.cell.2013.01.008. Cell. 2013. PMID: 23374348 Free PMC article.
Molecular determinants of drug-receptor binding kinetics.
Pan AC, Borhani DW, Dror RO, Shaw DE. Pan AC, et al. Drug Discov Today. 2013 Jul;18(13-14):667-73. doi: 10.1016/j.drudis.2013.02.007. Epub 2013 Feb 27. Drug Discov Today. 2013. PMID: 23454741 Review.
Transitions to catalytically inactive conformations in EGFR kinase.
Shan Y, Arkhipov A, Kim ET, Pan AC, Shaw DE. Shan Y, et al. Among authors: pan ac. Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7270-5. doi: 10.1073/pnas.1220843110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23576739 Free PMC article.
32 results