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The hippo signaling pathway in development and cancer.
Pan D. Pan D. Dev Cell. 2010 Oct 19;19(4):491-505. doi: 10.1016/j.devcel.2010.09.011. Dev Cell. 2010. PMID: 20951342 Free PMC article. Review.
A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease.
Cai J, Song X, Wang W, Watnick T, Pei Y, Qian F, Pan D. Cai J, et al. Among authors: pan d. Genes Dev. 2018 Jun 1;32(11-12):781-793. doi: 10.1101/gad.315127.118. Epub 2018 Jun 11. Genes Dev. 2018. PMID: 29891559 Free PMC article.
Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex.
Zheng Y, Liu B, Wang L, Lei H, Pulgar Prieto KD, Pan D. Zheng Y, et al. Among authors: pan d. Cell Rep. 2017 Dec 19;21(12):3612-3623. doi: 10.1016/j.celrep.2017.11.076. Cell Rep. 2017. PMID: 29262338 Free PMC article.
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.
Huang J, Wu S, Barrera J, Matthews K, Pan D. Huang J, et al. Among authors: pan d. Cell. 2005 Aug 12;122(3):421-34. doi: 10.1016/j.cell.2005.06.007. Cell. 2005. PMID: 16096061
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts.
Wu S, Huang J, Dong J, Pan D. Wu S, et al. Among authors: pan d. Cell. 2003 Aug 22;114(4):445-56. doi: 10.1016/s0092-8674(03)00549-x. Cell. 2003. PMID: 12941273
Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.
Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A. Serafimidis I, et al. Among authors: pan d. PLoS Biol. 2017 Mar 1;15(3):e2000949. doi: 10.1371/journal.pbio.2000949. eCollection 2017 Mar. PLoS Biol. 2017. PMID: 28248965 Free PMC article.
YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing.
Das A, Fischer RS, Pan D, Waterman CM. Das A, et al. Among authors: pan d. J Biol Chem. 2016 Mar 18;291(12):6096-110. doi: 10.1074/jbc.M115.708313. Epub 2016 Jan 12. J Biol Chem. 2016. PMID: 26757814 Free PMC article.
A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.
Shao D, Zhai P, Del Re DP, Sciarretta S, Yabuta N, Nojima H, Lim DS, Pan D, Sadoshima J. Shao D, et al. Among authors: pan d. Nat Commun. 2014;5:3315. doi: 10.1038/ncomms4315. Nat Commun. 2014. PMID: 24525530 Free PMC article.
NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart.
Matsuda T, Zhai P, Sciarretta S, Zhang Y, Jeong JI, Ikeda S, Park J, Hsu CP, Tian B, Pan D, Sadoshima J, Del Re DP. Matsuda T, et al. Among authors: pan d. Circ Res. 2016 Aug 19;119(5):596-606. doi: 10.1161/CIRCRESAHA.116.308586. Epub 2016 Jul 11. Circ Res. 2016. PMID: 27402866 Free PMC article.
The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6.
Qing Y, Yin F, Wang W, Zheng Y, Guo P, Schozer F, Deng H, Pan D. Qing Y, et al. Among authors: pan d. Elife. 2014 Jul 15;3:e02564. doi: 10.7554/eLife.02564. Elife. 2014. PMID: 25027438 Free PMC article.
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