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Cigarette smoke extracts induce overexpression of the proto-oncogenic gene interleukin-13 receptor α2 through activation of the PKA-CREB signaling pathway to trigger malignant transformation of lung vascular endothelial cells and angiogenesis.
Meng M, Liao H, Zhang B, Pan Y, Kong Y, Liu W, Yang P, Huo Z, Cao Z, Zhou Q. Meng M, et al. Among authors: pan y. Cell Signal. 2017 Feb;31:15-25. doi: 10.1016/j.cellsig.2016.12.006. Epub 2016 Dec 13. Cell Signal. 2017. PMID: 27986643
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